CAROVERINEHYDROCHLORIDE
- CAS No.
- 55750-05-5
- Chemical Name:
- CAROVERINEHYDROCHLORIDE
- Synonyms
- p 201-1;CAROVERINEHYDROCHLORIDE;Caroverine hydrochloride, 10 mM in DMSO;Caroverine hydrochloride >=98% (HPLC), solid;1-Diethylaminoethyl-3-(p-methoxybenzyl)-2-quinoxaone hydrochloride;1-(2-diethylaminoethyl)-3-[(4-methoxyphenyl)methyl]quinoxalin-2-one;1-(2-(Diethylamino)ethyl)-3-(4-methoxybenzyl)quinoxalin-2(1H)-one hydrochloride;2(1H)-Quinoxalinone, 1-(2-diethylamino)ethyl-3-(4-methoxybenzyl)-, hydrochloride;1-[2-(diethylamino)ethyl]-3-[(4-methoxyphenyl)methyl]quinoxalin-2-one,hydrochloride;1-(2-Diethylamino)ethyl-3-((4-methoxyphenyl)methyl)-2(1H)-quinoxalinone hydrochloride
- CBNumber:
- CB11229665
- Molecular Formula:
- C22H27N3O2
- Molecular Weight:
- 0
- MDL Number:
- MFCD01684929
- MOL File:
- 55750-05-5.mol
| storage temp. | 2-8°C |
|---|---|
| solubility | DMSO: >10mg/mL |
| form | solid |
| color | White to off-white |
| EWG's Food Scores | 1 |
| FDA UNII | OSH993362T |
CAROVERINEHYDROCHLORIDE price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Adipogen Life Sciences | CDX-C0258-M025 | Caroverine hydrochloride ≥99%(HPLC) | 55750-05-5 | 25mg | $165 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0008329 | CAROVERINE HYDROCHLORIDE 95.00% | 55750-05-5 | 10MG | $740.39 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0008329 | CAROVERINE HYDROCHLORIDE 95.00% | 55750-05-5 | 50MG | $1324.32 | 2021-12-16 | Buy |
| DC Chemicals | DC44933 | Caroverine hydrochloride >98% | 55750-05-5 | 1g | $1900 | 2021-12-16 | Buy |
| DC Chemicals | DC44933 | Caroverine hydrochloride >98% | 55750-05-5 | 250mg | $950 | 2021-12-16 | Buy |
CAROVERINEHYDROCHLORIDE Chemical Properties,Uses,Production
Uses
Caroverine hydrochloride is a potent, competitive and reversible antagonist of NMDA and AMPA glutamate receptor. Caroverine hydrochloride is also an antioxidant and calcium-blocking agent that exhibits vasorelaxant action. Caroverine hydrochloride can be used for the research of inner ear tinnitus[1][2][3].
in vivo
Caroverine (1.44 mg/rat; s.c; 1.0 mL/h for 72 h) attenuates impulse noise-induced hearing loss in the rat[4].
| Animal Model: | Sprague-Dawley rats of either sex (250-300 g) received impulse noise exposure[4] |
| Dosage: | 1.44 mg/rat |
| Administration: | 20 mg/mL; s.c. 1.0 mL/h for 72 h |
| Result: | Significantly protected the cochlea against impulse noise trauma. |
References
[1] Chen Z, et, al. Pharmacokinetics of caroverine in the inner ear and its effects on cochlear function after systemic and local administrations in Guinea pigs. Audiol Neurootol. Jan-Feb 2003;8(1):49-56. DOI:10.1159/000067893
[2] Denk DM, et, al. Caroverine in tinnitus treatment. A placebo-controlled blind study. Acta Otolaryngol. 1997 Nov;117(6):825-30. DOI:10.3109/00016489709114208
[3] Ishida Y, et, al. Vasorelaxant action of caroverine fumarate (a quinoxaline derivative), a calcium-blocking agent. Br J Pharmacol. 1980;71(1):343-8. DOI:10.1111/j.1476-5381.1980.tb10945.x
[4] Duan M, et, al. Low-dose, long-term caroverine administration attenuates impulse noise-induced hearing loss in the rat. Acta Otolaryngol. 2006 Dec;126(11):1140-7. DOI:10.1080/00016480500540519
CAROVERINEHYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32268 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
| Finetech Industry Limited | +86-27-8746-5837 +8619945049750 | info@finetechnology-ind.com | China | 9642 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10473 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38663 | 58 | |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8615965530500 | nickzhang@hangyubiotech.com | China | 10983 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43340 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +86-18621343501; +undefined18621343501 | product@acmec-e.com | China | 33338 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 |
View Lastest Price from CAROVERINEHYDROCHLORIDE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-19 | Caroverine hydrochloride
55750-05-5
|
US $39.00-133.00 / mg | 98.75% | 10g | TargetMol Chemicals Inc. |
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- Caroverine hydrochloride
55750-05-5
- US $39.00-133.00 / mg
- 98.75%
- TargetMol Chemicals Inc.