ChemicalBook >> CAS DataBase List >>(Z)-7-[(1S,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S,5Z)-3-hydroxyocta-1,5-dienyl]cyclopentyl]hept-5-enoic acid

(Z)-7-[(1S,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S,5Z)-3-hydroxyocta-1,5-dienyl]cyclopentyl]hept-5-enoic acid

(Z)-7-[(1S,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S,5Z)-3-hydroxyocta-1,5-dienyl]cyclopentyl]hept-5-enoic acid structure

CAS No.: 7045-31-0

Chemical Name:: (Z)-7-[(1S,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S,5Z)-3-hydroxyocta-1,5-dienyl]cyclopentyl]hept-5-enoic acid

Synonyms: 8-epi PGF3α;8-iso-PGF3alpha;8-iso Prostaglandin F3α;SAKGBZWJAIABSY-PJCXKLBTSA-N;8-iso Prostaglandin F3α Exclusive;8iso Prostaglandin F3α,8 iso Prostaglandin F3α,8-iso Prostaglandin F-3α;Prosta-5,13,17-trien-1-oic acid, 9,11,15-trihydroxy-, (5Z,8β,9α,11α,13E,15S,17Z)-;(Z)-7-[(1S,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S,5Z)-3-hydroxyocta-1,5-dienyl]cyclopentyl]hept-5-enoic acid

CBNumber:: CB11235660

Molecular Formula:: C20H32O5

Molecular Weight:: 352.47

MDL Number:

MOL File:: 7045-31-0.mol

MSDS File:: SDS

Last updated:2026-05-27 23:06:27

Request For Quotation

(Z)-7-[(1S,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S,5Z)-3-hydroxyocta-1,5-dienyl]cyclopentyl]hept-5-enoic acid Properties

Boiling point	541.653±50.00 °C(Press: 760.00 Torr)(predicted)
Density	1.171±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
storage temp.	Store at -20°C
solubility	10 mM Na2CO3: >6.5 mg/ml; DMF: >100 mg/ml; DMSO: >100 mg/ml; Ethanol: >100 mg/ml; PBS pH 7.2: >10 mg/ml
pka	4.762±0.10(predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS02,GHS07

Signal word

Danger

NFPA 704

	3
2		0

(Z)-7-[(1S,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S,5Z)-3-hydroxyocta-1,5-dienyl]cyclopentyl]hept-5-enoic acid price More Price(5)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	16992	8-iso Prostaglandin F3α ≥98%	7045-31-0	25μg	$303	2026-04-30	Buy
Cayman Chemical	16992	8-iso Prostaglandin F3α ≥98%	7045-31-0	50μg	$543	2026-04-30	Buy
Cayman Chemical	16992	8-iso Prostaglandin F3α ≥98%	7045-31-0	100μg	$962	2026-04-30	Buy
ChemScene	CS-0063446	8-iso Prostaglandin F3α	7045-31-0	50μg	$1175	2026-06-04	Buy
ChemScene	CS-0063446	8-iso Prostaglandin F3α	7045-31-0	100μg	$2083	2026-06-04	Buy

Product number	Packaging	Price	Buy
16992	25μg	$303	Buy
16992	50μg	$543	Buy
16992	100μg	$962	Buy
CS-0063446	50μg	$1175	Buy
CS-0063446	100μg	$2083	Buy

(Z)-7-[(1S,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S,5Z)-3-hydroxyocta-1,5-dienyl]cyclopentyl]hept-5-enoic acid Chemical Properties, Uses, Production

Description

8-iso PGF_3α is an isoprostane produced from the free-radical peroxidation of EPA. Little is known about the biological activity of 8-iso PGF_3α. There is one report that it is inactive in a TP receptor mediated assay of human platelet shape change, where 8-iso PGF_2α has an ED₅₀ value of 1 μM.¹

Uses

8-iso PGF3α is an isoprostane produced from the free-radical peroxidation of EPA. Little is known about the biological activity of 8-iso PGF3α. There is one report that it is inactive in a TP receptor mediated assay of human platelet shape change, where 8-iso PGF2α has an ED50 value of 1 μM.

Definition

ChEBI: 8-Iso-PGF3alpha is a prostanoid.

References

1. Praticò, D., Smith, E.M., Violi, F., et al. Local amplification of platelet function by 8-epi prostaglandin F_2α is not mediated by thromboxane receptor isoforms J. Biol. Chem. 271(25),14916-14924(1996).

(Z)-7-[(1S,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S,5Z)-3-hydroxyocta-1,5-dienyl]cyclopentyl]hept-5-enoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

(Z)-7-[(1S,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S,5Z)-3-hydroxyocta-1,5-dienyl]cyclopentyl]hept-5-enoic acid Suppliers

Global Suppliers ( 14)

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9799	58
TargetMol Chemicals Inc.	+1-781-999-5354; +1-00000000000	marketing@targetmol.com	United States	32431	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11123	58
TargetMol Chemicals Inc.	4008200310 15002144251	marketing@tsbiochem.com	China	24951	58

Supplier	Advantage
Shanghai EFE Biological Technology Co., Ltd.	58
TargetMol Chemicals Inc.	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	58
TargetMol Chemicals Inc.	58

View Latest Price from (Z)-7-[(1S,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S,5Z)-3-hydroxyocta-1,5-dienyl]cyclopentyl]hept-5-enoic acid manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-04-22	8-iso Prostaglandin F3α 7045-31-0	$1780.00			10g	TargetMol Chemicals Inc.

8-iso Prostaglandin F3α
7045-31-0
$1780.00
TargetMol Chemicals Inc.

7045-31-0 ((Z)-7-[(1S,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S,5Z)-3-hydroxyocta-1,5-dienyl]cyclopentyl]hept-5-enoic acid) Related Search:

(Z)-7-[(1S,2R,3R,5S)-3,5-dihydroxy-2-(3-oxooctyl)cyclopentyl]hept-5-enoic acid 8-Epi PGF2alpha-d4 2,3-Di-nor-8-isoprostaglandin F2A 8-iso-16-cyclohexyl-tetranor Prostaglandin E2 Cyclopentanepentanoic acid, 3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-1-octen-1-yl]-, (1S,2R,3R,5S)-

Bimatoprost

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(Z)-7-[(1S,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S,5Z)-3-hydroxyocta-1,5-dienyl]cyclopentyl]hept-5-enoic acid 8-iso-PGF3alpha 8-iso Prostaglandin F3α 8-iso Prostaglandin F3α Exclusive SAKGBZWJAIABSY-PJCXKLBTSA-N Prosta-5,13,17-trien-1-oic acid, 9,11,15-trihydroxy-, (5Z,8β,9α,11α,13E,15S,17Z)- 8-epi PGF3α 8iso Prostaglandin F3α,8 iso Prostaglandin F3α,8-iso Prostaglandin F-3α 7045-31-0