2-METHYL-3-NITROIMIDAZO[1,2-A]PYRIDINE
- CAS No.
- 34165-09-8
- Chemical Name:
- 2-METHYL-3-NITROIMIDAZO[1,2-A]PYRIDINE
- Synonyms
- 2-METHYL-3-NITROIMIDAZO[1,2-A]PYRIDINE;Imidazo[1,2-a]pyridine, 2-methyl-3-nitro-;2-Methyl-3-nitroimidazo[1,2-a]pyridine[N/A]
- CBNumber:
- CB11253455
- Molecular Formula:
- C8H7N3O2
- Molecular Weight:
- 177.16
- MDL Number:
- MFCD09800612
- MOL File:
- 34165-09-8.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HS Code | 2933998090 |
2-METHYL-3-NITROIMIDAZO[1,2-A]PYRIDINE price More Price(36)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR450076 | 2-Methyl-3-nitroimidazo[1,2-a]pyridine 95% | 34165-09-8 | 100mg | $41 | 2026-06-04 | Buy |
| Apolloscientific | OR450076 | 2-Methyl-3-nitroimidazo[1,2-a]pyridine 95% | 34165-09-8 | 250mg | $54 | 2026-06-04 | Buy |
| Apolloscientific | OR450076 | 2-Methyl-3-nitroimidazo[1,2-a]pyridine 95% | 34165-09-8 | 500mg | $100 | 2026-06-04 | Buy |
| Apolloscientific | OR450076 | 2-Methyl-3-nitroimidazo[1,2-a]pyridine 95% | 34165-09-8 | 1g | $173 | 2026-06-04 | Buy |
| Matrix Scientific | 085990 | 2-Methyl-3-nitroimidazo[1,2-a]pyridine | 34165-09-8 | 250.00mg | $23 | 2026-05-18 | Buy |
2-METHYL-3-NITROIMIDAZO[1,2-A]PYRIDINE Chemical Properties,Uses,Production
Synthesis
934-37-2
34165-09-8
General procedure for the synthesis of 2-methyl-3-nitroimidazo[1,2-a]pyridine from 2-methylimidazo[1,2-a]pyridine: to a cooled solution of 2-methylimidazo[1,2-a]pyridine (380 mg, 2.88 mmol) in concentrated sulfuric acid (6 mL) was slowly added nitric acid (472 μL, density = 1.38 g/mL) dropwise. The reaction mixture was stirred for 2 h at room temperature and then cooled in an ice bath, followed by slow addition of saturated aqueous Na2CO3 solution adjusted to alkaline. The reaction mixture was extracted with dichloromethane (CH2Cl2) and the organic layer was dried with anhydrous magnesium sulfate (MgSO4), filtered and concentrated under reduced pressure to give 330 mg (1.82 mmol, 65% yield) of 2-methyl-3-nitroimidazo[1,2-a]pyridine as a brown solid.LRMS (m/z): 178 ([M+H]+).
References
[1] Bioorganic and Medicinal Chemistry, 2013, vol. 21, # 22, p. 7155 - 7164
[2] Patent: EP2848615, 2015, A1. Location in patent: Paragraph 0099
[3] Chemical and Pharmaceutical Bulletin, 2001, vol. 49, # 12, p. 1631 - 1635
2-METHYL-3-NITROIMIDAZO[1,2-A]PYRIDINE Preparation Products And Raw materials
2-METHYL-3-NITROIMIDAZO[1,2-A]PYRIDINE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
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