Methyl 6-amino-3-bromopicolinate
- CAS No.
- 178876-83-0
- Chemical Name:
- Methyl 6-amino-3-bromopicolinate
- Synonyms
- Methyl 6-amino-3-bromopic;Methyl 6-amino-3-bromopicolinate;Methyl 6-Amino 3-Bromo 2-Picolinate;methyl 6-amino-3-bromo-2-pyridinecarboxylate;Methyl 6-amino-3-bromopyridine-2-carboxylate;Methyl 6-amino-3-bromopicolinate ISO 9001：2015 REACH;6-Amino-3-bromo-pyridine-2-carboxylic acid methyl ester;methyl 3-bromo-6-imino-1,6-dihydropyridine-2-carboxylate;2-Pyridinecarboxylic acid, 6-amino-3-bromo-, methyl ester;6-amino-3-bromo-2-Pyridinecarboxylic acid methyl ester (9CI ACI)
- CBNumber:
- CB11263458
- Molecular Formula:
- C7H7BrN2O2
- Molecular Weight:
- 231.05
- MDL Number:
- MFCD09800897
- MOL File:
- 178876-83-0.mol
- MSDS File:
- SDS
| Boiling point | 333.4±37.0 °C(Predicted) |
|---|---|
| Density | 1.662±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| pka | 1.12±0.10(Predicted) |
| form | solid |
| color | Off white |
| InChI | InChI=1S/C7H7BrN2O2/c1-12-7(11)6-4(8)2-3-5(9)10-6/h2-3H,1H3,(H2,9,10) |
| InChIKey | YJUKTIBOUBUOJH-UHFFFAOYSA-N |
| SMILES | C1(C(OC)=O)=NC(N)=CC=C1Br |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| Hazard Codes | Xi |
| HS Code | 2933399990 |
Methyl 6-amino-3-bromopicolinate price More Price(40)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR11647 | Methyl 6-amino-3-bromopyridine-2-carboxylate 97% | 178876-83-0 | 1g | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR11647 | Methyl 6-amino-3-bromopyridine-2-carboxylate 97% | 178876-83-0 | 5g | $47 | 2026-06-04 | Buy |
| Apolloscientific | OR11647 | Methyl 6-amino-3-bromopyridine-2-carboxylate 97% | 178876-83-0 | 25g | $230 | 2026-06-04 | Buy |
| Apolloscientific | OR11647 | Methyl 6-amino-3-bromopyridine-2-carboxylate 97% | 178876-83-0 | 100g | $918 | 2026-06-04 | Buy |
| Synthonix | M45637 | Methyl 6-amino-3-bromopicolinate 97% | 178876-83-0 | 250mg | $17 | 2026-05-06 | Buy |
Methyl 6-amino-3-bromopicolinate Chemical Properties, Uses, Production
Synthesis
36052-26-3
178876-83-0
178876-82-9
General procedure for the synthesis of methyl 6-amino-3-bromopyridine-2-carboxylate and methyl 5-bromo-6-aminopyridine-2-carboxylate from methyl 6-aminopyridine-2-carboxylate: (d) Synthesis of methyl 6-amino-5-bromopyridine-2-carboxylate: to a solution of methyl 6-aminopyridine-2-carboxylate (10 g, 66.0 mmol) in chloroform (450 mL) was slowly added a solution of bromine (3.4 mL, 66.0 mmol) in chloroform (100 mL) at room temperature, and the reaction mixture was stirred for 40 hours. After completion of the reaction, the reaction mixture was diluted with chloroform and washed sequentially with saturated sodium thiosulfate solution and water. The organic phase was dried with anhydrous sodium sulfate and concentrated under reduced pressure to remove the solvent. The residue was purified by silica gel column chromatography using ethyl acetate/hexane as eluent to afford methyl 6-amino-3-bromopyridine-2-carboxylate as a yellow solid (3.3 g, 22% yield). Mass spectrum (ESI) m/e: 231.0 [M+H]+. 1H NMR (CDCl3, 400MHz): δ (ppm) = 7.76 (d, J = 7.88Hz, 1H), 7.34 (d, J = 7.92Hz, 1H), 5.23 (s, 2H), 3.94 (s, 3H). d) Isolation of methyl 6-amino-3-bromopyridine-2-carboxylate: In step d) above, the isomer methyl 6-amino-3-bromopyridine-2-carboxylate (3.0 g, 19% yield) was also isolated as a by-product. Mass spectrum (ESI) m/e: 231.2 [M+H]+. 1H NMR (CDCl3, 400MHz): δ (ppm) = 7.60 (d, J = 8.72Hz, 1H), 6.47 (d, J = 7.88Hz, 1H), 4.71 (s, 2H), 3.94 (s, 3H).
References
[1] Journal of Organic Chemistry, 1996, vol. 61, # 14, p. 4623 - 4633
[2] Organic Process Research and Development, 2010, vol. 14, # 1, p. 263 - 271
[3] Tetrahedron Letters, 2010, vol. 51, # 38, p. 5035 - 5037
[4] Patent: US2011/190269, 2011, A1. Location in patent: Page/Page column 61-62
[5] Patent: WO2011/92272, 2011, A1. Location in patent: Page/Page column 129; 130
Methyl 6-amino-3-bromopicolinate Preparation Products And Raw materials
Methyl 6-amino-3-bromopicolinate Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Wuhan Luohua Medical Technology Co.,Ltd. | 13477084141; 13477084141 | sales@luohuapharm.com | China | 468 | 60 |
| Shanghai Lingfu Pharmaceutical Research Co. LTD | +86(21)5895 0110 19945755304 | sales@chemany.com | China | 9981 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
| Jia Xing Isenchem Co.,Ltd | 0573-85285100 18627885956 | isenchem@163.com | China | 9389 | 66 |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
View Latest Price from Methyl 6-amino-3-bromopicolinate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-20 | Methyl 6-amino-3-bromopicolinate
178876-83-0
|
$1.10 | 1g | 99.00% | 100 Tons min | Dideu Industries Group Limited | |
 |
2020-05-13 | Methyl 6-amino-3-bromopicolinate
178876-83-0
|
1KG | 99.0% | 500 MT | Shaanxi Dideu Medichem Co. Ltd | ||
 |
2020-01-13 | Methyl 6-amino-3-bromopicolinate
178876-83-0
|
$1.00 | 1KG | 99% | 100KG | Career Henan Chemical Co |
-
- Methyl 6-amino-3-bromopicolinate
178876-83-0
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- Methyl 6-amino-3-bromopicolinate
178876-83-0
- 99.0%
- Shaanxi Dideu Medichem Co. Ltd
-
- Methyl 6-amino-3-bromopicolinate
178876-83-0
- $1.00
- 99%
- Career Henan Chemical Co
