Methyl 6-amino-3-bromopicolinate
- CAS No.
- 178876-83-0
- Chemical Name:
- Methyl 6-amino-3-bromopicolinate
- Synonyms
- Methyl 6-amino-3-bromopicolinate;Methyl 6-Amino 3-Bromo 2-Picolinate;methyl 6-amino-3-bromo-2-pyridinecarboxylate;Methyl 6-amino-3-bromopyridine-2-carboxylate;Methyl 6-amino-3-bromopicolinate ISO 9001：2015 REACH;6-Amino-3-bromo-pyridine-2-carboxylic acid methyl ester;methyl 3-bromo-6-imino-1,6-dihydropyridine-2-carboxylate;2-Pyridinecarboxylic acid, 6-amino-3-bromo-, methyl ester;6-amino-3-bromo-2-Pyridinecarboxylic acid methyl ester (9CI ACI);2-Pyridinecarboxylic acid, 6-amino-3-bromo-, methyl ester (9CI, ACI)
- CBNumber:
- CB11263458
- Molecular Formula:
- C7H7BrN2O2
- Molecular Weight:
- 231.05
- MDL Number:
- MFCD09800897
- MOL File:
- 178876-83-0.mol
- MSDS File:
- SDS
| Boiling point | 333.4±37.0 °C(Predicted) |
|---|---|
| Density | 1.662±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| pka | 1.12±0.10(Predicted) |
| form | solid |
| color | Off white |
| InChI | InChI=1S/C7H7BrN2O2/c1-12-7(11)6-4(8)2-3-5(9)10-6/h2-3H,1H3,(H2,9,10) |
| InChIKey | YJUKTIBOUBUOJH-UHFFFAOYSA-N |
| SMILES | C1(C(OC)=O)=NC(N)=CC=C1Br |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| Hazard Codes | Xi |
| HS Code | 2933399990 |
Methyl 6-amino-3-bromopicolinate price More Price(25)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | M289408 | Methyl6-Amino-3-bromopyridine-2-carboxylate | 178876-83-0 | 500mg | $155 | 2021-12-16 | Buy |
| TRC | M289408 | Methyl6-Amino-3-bromopyridine-2-carboxylate | 178876-83-0 | 50mg | $45 | 2021-12-16 | Buy |
| TRC | M289408 | Methyl6-Amino-3-bromopyridine-2-carboxylate | 178876-83-0 | 100mg | $60 | 2021-12-16 | Buy |
| AK Scientific | W3896 | Methyl6-amino-3-bromopyridine-2-carboxylate | 178876-83-0 | 5g | $355 | 2021-12-16 | Buy |
| SynQuest Laboratories | 4H58-9-00 | Methyl 6-amino-3-bromopyridine-2-carboxylate | 178876-83-0 | 5G | $552 | 2021-12-16 | Buy |
Methyl 6-amino-3-bromopicolinate Chemical Properties,Uses,Production
Synthesis
36052-26-3
178876-83-0
178876-82-9
General procedure for the synthesis of methyl 6-amino-3-bromopyridine-2-carboxylate and methyl 5-bromo-6-aminopyridine-2-carboxylate from methyl 6-aminopyridine-2-carboxylate: (d) Synthesis of methyl 6-amino-5-bromopyridine-2-carboxylate: to a solution of methyl 6-aminopyridine-2-carboxylate (10 g, 66.0 mmol) in chloroform (450 mL) was slowly added a solution of bromine (3.4 mL, 66.0 mmol) in chloroform (100 mL) at room temperature, and the reaction mixture was stirred for 40 hours. After completion of the reaction, the reaction mixture was diluted with chloroform and washed sequentially with saturated sodium thiosulfate solution and water. The organic phase was dried with anhydrous sodium sulfate and concentrated under reduced pressure to remove the solvent. The residue was purified by silica gel column chromatography using ethyl acetate/hexane as eluent to afford methyl 6-amino-3-bromopyridine-2-carboxylate as a yellow solid (3.3 g, 22% yield). Mass spectrum (ESI) m/e: 231.0 [M+H]+. 1H NMR (CDCl3, 400MHz): δ (ppm) = 7.76 (d, J = 7.88Hz, 1H), 7.34 (d, J = 7.92Hz, 1H), 5.23 (s, 2H), 3.94 (s, 3H). d) Isolation of methyl 6-amino-3-bromopyridine-2-carboxylate: In step d) above, the isomer methyl 6-amino-3-bromopyridine-2-carboxylate (3.0 g, 19% yield) was also isolated as a by-product. Mass spectrum (ESI) m/e: 231.2 [M+H]+. 1H NMR (CDCl3, 400MHz): δ (ppm) = 7.60 (d, J = 8.72Hz, 1H), 6.47 (d, J = 7.88Hz, 1H), 4.71 (s, 2H), 3.94 (s, 3H).
References
[1] Journal of Organic Chemistry, 1996, vol. 61, # 14, p. 4623 - 4633
[2] Organic Process Research and Development, 2010, vol. 14, # 1, p. 263 - 271
[3] Tetrahedron Letters, 2010, vol. 51, # 38, p. 5035 - 5037
[4] Patent: US2011/190269, 2011, A1. Location in patent: Page/Page column 61-62
[5] Patent: WO2011/92272, 2011, A1. Location in patent: Page/Page column 129; 130
Methyl 6-amino-3-bromopicolinate Preparation Products And Raw materials
Methyl 6-amino-3-bromopicolinate Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5906 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29800 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| KARMEL TECHNOLOGY (HK) CO.,LIMITED | +8618795957998 | karmelhk@126.com | CHINA | 2886 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 20386 | 58 |
View Lastest Price from Methyl 6-amino-3-bromopicolinate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2021-08-24 | Methyl 6-amino-3-bromopicolinate
178876-83-0
|
US $1.10 / g | 1g | 99.00% | 100 Tons min | Dideu Industries Group Limited | |
 |
2020-05-13 | Methyl 6-amino-3-bromopicolinate
178876-83-0
|
US $0.00-0.00 / Kg | 1KG | 99.0% | 500 MT | Shaanxi Dideu Medichem Co. Ltd | |
 |
2020-01-13 | Methyl 6-amino-3-bromopicolinate
178876-83-0
|
US $1.00 / KG | 1KG | 99% | 100KG | Career Henan Chemical Co |
-
- Methyl 6-amino-3-bromopicolinate
178876-83-0
- US $1.10 / g
- 99.00%
- Dideu Industries Group Limited
-
- Methyl 6-amino-3-bromopicolinate
178876-83-0
- US $0.00-0.00 / Kg
- 99.0%
- Shaanxi Dideu Medichem Co. Ltd
-
- Methyl 6-amino-3-bromopicolinate
178876-83-0
- US $1.00 / KG
- 99%
- Career Henan Chemical Co
