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ChemicalBook >> CAS DataBase List >>2,4-Pyrimidinediamine, N2-[2-fluoro-5-(1-piperazinylmethyl)phenyl]-N4-(8-methyl-4-cinnolinyl)-

2,4-Pyrimidinediamine, N2-[2-fluoro-5-(1-piperazinylmethyl)phenyl]-N4-(8-methyl-4-cinnolinyl)-

2,4-Pyrimidinediamine, N2-[2-fluoro-5-(1-piperazinylmethyl)phenyl]-N4-(8-methyl-4-cinnolinyl)- Structure
2,4-Pyrimidinediamine, N2-[2-fluoro-5-(1-piperazinylmethyl)phenyl]-N4-(8-methyl-4-cinnolinyl)- structure
CAS No.
2785430-82-0
Chemical Name:
2,4-Pyrimidinediamine, N2-[2-fluoro-5-(1-piperazinylmethyl)phenyl]-N4-(8-methyl-4-cinnolinyl)-
Synonyms
ALK5-IN-26;2,4-Pyrimidinediamine, N2-[2-fluoro-5-(1-piperazinylmethyl)phenyl]-N4-(8-methyl-4-cinnolinyl)-
CBNumber:
CB112689256
Molecular Formula:
C24H25FN8
Molecular Weight:
444.51
MDL Number:
MOL File:
2785430-82-0.mol
MSDS File:
SDS
Last updated:2026-05-11 16:31:51
Request For Quotation

2,4-Pyrimidinediamine, N2-[2-fluoro-5-(1-piperazinylmethyl)phenyl]-N4-(8-methyl-4-cinnolinyl)- Properties

Boiling point 661.9±65.0 °C(Predicted)
Density 1.341±0.06 g/cm3(Predicted)
pka 9.11±0.10(Predicted)

2,4-Pyrimidinediamine, N2-[2-fluoro-5-(1-piperazinylmethyl)phenyl]-N4-(8-methyl-4-cinnolinyl)- Chemical Properties, Uses, Production

Uses

ALK5-IN-26 (EX-22) is an ALK (Activin receptor-like kinase) inhibitor. ALK5-IN-26 inhibits ALK5 with an IC50 value ≤10 nM. ALK5-IN-26 can be used for the research of cancer[1].

References

[1] Franz B, et al. ALK-5 INHIBITORS AND USES THEREOF. WO/2022/126133 A1. 2022.

2,4-Pyrimidinediamine, N2-[2-fluoro-5-(1-piperazinylmethyl)phenyl]-N4-(8-methyl-4-cinnolinyl)- Preparation Products And Raw materials

Raw materials

Preparation Products

2,4-Pyrimidinediamine, N2-[2-fluoro-5-(1-piperazinylmethyl)phenyl]-N4-(8-methyl-4-cinnolinyl)- Suppliers

Global Suppliers ( 2)
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
TargetMol Chemicals Inc. 13564774135 marketing@targetmol.com United States 19950 58
Supplier Advantage
TargetMol Chemicals Inc. 58
TargetMol Chemicals Inc. 58

View Latest Price from 2,4-Pyrimidinediamine, N2-[2-fluoro-5-(1-piperazinylmethyl)phenyl]-N4-(8-methyl-4-cinnolinyl)- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
ALK5-IN-26 pictures 2026-05-11 ALK5-IN-26
2785430-82-0
 $1520.00-2500.00 10g TargetMol Chemicals Inc.
  • ALK5-IN-26 pictures
  • ALK5-IN-26
    2785430-82-0
  • $1520.00-2500.00
  • TargetMol Chemicals Inc.

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2,4-Pyrimidinediamine, N2-[2-fluoro-5-(1-piperazinylmethyl)phenyl]-N4-(8-methyl-4-cinnolinyl)- ALK5-IN-26 2785430-82-0