Ethane-1,1,2,2-d4-sulfonic acid, 2-[[(3α,5β,7β)-3,7-dihydroxy-24-oxocholan-24-yl]amino]-
![Ethane-1,1,2,2-d4-sulfonic acid, 2-[[(3α,5β,7β)-3,7-dihydroxy-24-oxocholan-24-yl]amino]- Structure](CAS/20211123/GIF/2573035-17-1.gif)
- CAS No.
- 2573035-17-1
- Chemical Name:
- Ethane-1,1,2,2-d4-sulfonic acid, 2-[[(3α,5β,7β)-3,7-dihydroxy-24-oxocholan-24-yl]amino]-
- Synonyms
- Ethane-1,1,2,2-d4-sulfonic acid, 2-[[(3α,5β,7β)-3,7-dihydroxy-24-oxocholan-24-yl]amino]-
- CBNumber:
- CB112797830
- Molecular Formula:
- C26H45NO6S
- Molecular Weight:
- 499.71
- MDL Number:
- MOL File:
- 2573035-17-1.mol
- MSDS File:
- SDS
Ethane-1,1,2,2-d4-sulfonic acid, 2-[[(3α,5β,7β)-3,7-dihydroxy-24-oxocholan-24-yl]amino]- price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 39851 | Tauro-d4-ursodeoxycholic Acid ≥99%deuteratedforms(d1-d4) | 2573035-17-1 | 1mg | $146 | 2026-04-30 | Buy |
| Cayman Chemical | 39851 | Tauro-d4-ursodeoxycholic Acid ≥99%deuteratedforms(d1-d4) | 2573035-17-1 | 5mg | $653 | 2026-04-30 | Buy |
| Cayman Chemical | 39851 | Tauro-d4-ursodeoxycholic Acid ≥99%deuteratedforms(d1-d4) | 2573035-17-1 | 10mg | $1087 | 2026-04-30 | Buy |
| ChemScene | CS-0438547 | Tauroursodeoxycholate-d4-1 | 2573035-17-1 | 1mg | $357 | 2026-06-04 | Buy |
| ChemScene | CS-0438547 | Tauroursodeoxycholate-d4-1 | 2573035-17-1 | 5mg | $1414 | 2026-06-04 | Buy |
Ethane-1,1,2,2-d4-sulfonic acid, 2-[[(3α,5β,7β)-3,7-dihydroxy-24-oxocholan-24-yl]amino]- Chemical Properties, Uses, Production
Uses
Tauroursodeoxycholate-d4-1 is the deuterium labeled Tauroursodeoxycholate. Tauroursodeoxycholate (Tauroursodeoxycholic acid) is an endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as caspase-3 and caspase-12. Tauroursodeoxycholate also inhibits ERK.
References
[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. DOI:10.1177/1060028018797110
[2] Kim SY, et al. Tauroursodeoxycholate (TUDCA) inhibits neointimal hyperplasia by suppression of ERK viaPKCα-mediated MKP-1 induction. Cardiovasc Res. 2011 Nov 1;92(2):307-16. DOI:10.1093/cvr/cvr219
[3] Qin Y, et al. Tauroursodeoxycholic Acid Attenuates Angiotensin II Induced Abdominal Aortic Aneurysm Formation in Apolipoprotein E-deficient Mice by Inhibiting Endoplasmic Reticulum Stress. Eur J Vasc Endovasc Surg. 2017 Mar;53(3):337-345. DOI:10.1016/j.ejvs.2016.10.026
[4] BEUERS U. Effects of bile acids on hepatocellular signaling and secretion.[J]. Yale Journal of Biology and Medicine, 1997, 70 4: 341-346.
[5] JEFFREY H BOATRIGHT. Bile acids in treatment of ocular disease.[J]. Journal of ocular biology, diseases, and informatics, 2009, 2 3: 149-159. DOI: 10.1007/s12177-009-9030-x
[6] SHEILA VANG. The Unexpected Uses of Urso- and Tauroursodeoxycholic Acid in the Treatment of Non-liver Diseases.[J]. Global Advances in Health and Medicine, 2014, 3 3: 58-69. DOI: 10.7453/gahmj.2014.017
Ethane-1,1,2,2-d4-sulfonic acid, 2-[[(3α,5β,7β)-3,7-dihydroxy-24-oxocholan-24-yl]amino]- Preparation Products And Raw materials
Raw materials
Preparation Products
Ethane-1,1,2,2-d4-sulfonic acid, 2-[[(3α,5β,7β)-3,7-dihydroxy-24-oxocholan-24-yl]amino]- Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ChengDu SinoStandards Bio-Tech Co.,Ltd. ， | 028-83243028 19136088901 | sinostandards@163.com | China | 4979 | 58 |
| LGC Science (Shanghai) Ltd. | 17717235263 | offer.de@lgcgroup.com | China | 19036 | 58 |
| CHINA ISOTOPE CO., LIMITED | 02151600108 13062666369 | info@isotopechem.com | China | 4721 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11963 | 58 |
| Supplier | Advantage |
|---|---|
| ChengDu SinoStandards Bio-Tech Co.,Ltd. ， | 58 |
| LGC Science (Shanghai) Ltd. | 58 |
| CHINA ISOTOPE CO., LIMITED | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 58 |
