lychnopholide
- CAS No.
- 77448-64-7
- Chemical Name:
- lychnopholide
- Synonyms
- lychnopholide;(Z)-2-Methyl-2-butenoic acid (3aR,4S,6R,10Z,11aR)-2,3,3a,4,5,6,7,11a-octahydro-6,10-dimethyl-3-methylene-2,7-dioxo-6,9-epoxycyclodeca[b]furan-4-yl ester
- CBNumber:
- CB11307684
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD29765876
- MOL File:
- 77448-64-7.mol
lychnopholide Chemical Properties,Uses,Production
Description
Lychnopholide is isolated from Vanillosmopsis erythropappa.
Uses
Lychnopholide is a sesquiterpene lactone derived from the Asteraceae, Lychnopholide exhibits anti-trypanosomal activity against Trypanosoma cruzi. lychnopholide encapsulated in nanocapsules reduces its toxicity to mammalian cells. Lychnopholide ameliorates Chagas disease in mouse models[1].
References
[1] Milagre MM, et al., Lychnopholide loaded in surface modified polylactide nanocapsules (LYC-PLA-PEG-NC) cure mice infected by Trypanosoma cruzi strain a prototype of resistance to benznidazole and nifurtimox: First insights of its mechanism of action. Exp Parasitol. 2023 Dec;255:108647. DOI:10.1016/j.exppara.2023.108647
lychnopholide Preparation Products And Raw materials
Raw materials
Preparation Products
lychnopholide Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38663 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |