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ChemicalBook >> CAS DataBase List >>4-Quinolinamine, 7-iodo-N-(3,4,5-trimethoxyphenyl)-

4-Quinolinamine, 7-iodo-N-(3,4,5-trimethoxyphenyl)-

4-Quinolinamine, 7-iodo-N-(3,4,5-trimethoxyphenyl)- Structure
4-Quinolinamine, 7-iodo-N-(3,4,5-trimethoxyphenyl)- structure
CAS No.
2361545-75-5
Chemical Name:
4-Quinolinamine, 7-iodo-N-(3,4,5-trimethoxyphenyl)-
Synonyms
PKN3-IN-1;PKN3 inhibitor compound 16;4-Quinolinamine, 7-iodo-N-(3,4,5-trimethoxyphenyl)-
CBNumber:
CB113155491
Molecular Formula:
C18H17IN2O3
Molecular Weight:
436.24
MDL Number:
MOL File:
2361545-75-5.mol
MSDS File:
SDS
Last updated:2025-08-21 14:05:29
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4-Quinolinamine, 7-iodo-N-(3,4,5-trimethoxyphenyl)- Properties

Boiling point 502.5±50.0 °C(Predicted)
Density 1.575±0.06 g/cm3(Predicted)
solubility Acetonitrile: Slightly soluble: 0.1-1 mg/ml
DMSO: Sparingly soluble: 1-10 mg/ml
pka 5.71±0.50(Predicted)

4-Quinolinamine, 7-iodo-N-(3,4,5-trimethoxyphenyl)- price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 41437 PKN3 Inhibitor Compound 16 ≥98% 2361545-75-5 1mg $36 2026-04-30 Buy
Cayman Chemical 41437 PKN3 Inhibitor Compound 16 ≥98% 2361545-75-5 5mg $159 2026-04-30 Buy
Cayman Chemical 41437 PKN3 Inhibitor Compound 16 ≥98% 2361545-75-5 10mg $282 2026-04-30 Buy
Cayman Chemical 41437 PKN3 Inhibitor Compound 16 ≥98% 2361545-75-5 25mg $616 2026-04-30 Buy
ChemScene CS-1238156 PKN3-IN-1 98.97% 2361545-75-5 1mg $43 2026-06-04 Buy
Product number Packaging Price Buy
41437 1mg $36 Buy
41437 5mg $159 Buy
41437 10mg $282 Buy
41437 25mg $616 Buy
CS-1238156 1mg $43 Buy

4-Quinolinamine, 7-iodo-N-(3,4,5-trimethoxyphenyl)- Chemical Properties, Uses, Production

Uses

PKN3-IN-1 (compound 16) inhibits PKN3 (serine/threonine protein kinase 3) and GAK (cyclin G-associated kinase) with IC50 of 0.014 μM and Ki of 0.0044 μM respectively. PKN3-IN-1 is a potential tool compound to study the cell biology of PKN3 and its role in pancreatic and prostate cancer and T-cell acute lymphoblastic leukemia [1].

References

[1] Asquith CRM, et al. Identification of 4-Anilinoquin(az)oline as a Cell-Active Protein Kinase Novel 3 (PKN3) Inhibitor Chemotype. ChemMedChem. 2022 Jun 20;17(12):e202200161. DOI:10.1002/cmdc.202200161

[2] Asquith CRM, et al. Identification and Optimization of 4-Anilinoquinolines as Inhibitors of Cyclin G Associated Kinase. ChemMedChem. 2018 Jan 8;13(1):48-66.
[3] DR. CHRISTOPHER R. M. ASQUITH. Design and Analysis of the 4-Anilinoquin(az)oline Kinase Inhibition Profiles of GAK/SLK/STK10 Using Quantitative Structure-Activity Relationships[J]. ChemMedChem, 2019, 15 1: 26-49. DOI: 10.1002/cmdc.201900521

[4] SIRLE SAUL . Potent antiviral activity of novel multi-substituted 4-anilinoquin(az)olines[J]. Bioorganic & Medicinal Chemistry Letters, 2020, 30 16: Article 127284. DOI: 10.1016/j.bmcl.2020.127284

4-Quinolinamine, 7-iodo-N-(3,4,5-trimethoxyphenyl)- Preparation Products And Raw materials

Raw materials

Preparation Products

4-Quinolinamine, 7-iodo-N-(3,4,5-trimethoxyphenyl)- Suppliers

Global Suppliers ( 4)
Supplier Tel Email Country ProdList Advantage
Shanghai Chaolan Chemical Technology Center QQ：65489617 13301690235 Sales@ATKchemical.com China 9729 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11963 58
TargetMol 400-821-0310 15002144251 xuexiang.shao@tsbiochem.com China 29128 58
Supplier Advantage
Shanghai Chaolan Chemical Technology Center 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
TargetMol 58

2361545-75-5 (4-Quinolinamine, 7-iodo-N-(3,4,5-trimethoxyphenyl)-) Related Search:

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4-Quinolinamine, 7-iodo-N-(3,4,5-trimethoxyphenyl)- PKN3 inhibitor compound 16 PKN3-IN-1 2361545-75-5