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4-dehydrowithaferin A

CAS No.
6850-30-2
Chemical Name:
4-dehydrowithaferin A
Synonyms
4-oxo Withaferin A;4-dehydrowithaferin A;Ergosta-2,24-dien-26-oic acid, 5,6-epoxy-22,27-dihydroxy-1,4-dioxo-, δ-lactone, (5β,6β,22R)-
CBNumber:
CB11316574
Molecular Formula:
C28H36O6
Molecular Weight:
468.58
MDL Number:
MOL File:
6850-30-2.mol
MSDS File:
SDS
Last updated:2026-05-11 15:21:01

4-dehydrowithaferin A Properties

storage temp. Store at -20°C
solubility DMF: 5mg/mL; DMSO: 5mg/mL; DMSO:PBS (pH 7.2) (1:1): 0.5mg/mL
form A crystalline solid

4-dehydrowithaferin A price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 28295 4-oxo Withaferin A ≥98% 6850-30-2 1mg $96 2026-04-30 Buy
Cayman Chemical 28295 4-oxo Withaferin A ≥98% 6850-30-2 5mg $335 2026-04-30 Buy
Cayman Chemical 28295 4-oxo Withaferin A ≥98% 6850-30-2 10mg $526 2026-04-30 Buy
Biosynth GAA85030 4-Dehydrowithaferin A 6850-30-2 10mg $768.5 2026-06-04 Buy
Biosynth GAA85030 4-Dehydrowithaferin A 6850-30-2 25mg $1441 2026-06-04 Buy
Product number Packaging Price Buy
28295 1mg $96 Buy
28295 5mg $335 Buy
28295 10mg $526 Buy
GAA85030 10mg $768.5 Buy
GAA85030 25mg $1441 Buy

4-dehydrowithaferin A Chemical Properties, Uses, Production

Description

4-oxo Withaferin A is a derivative of the steroidal lactone withaferin A that has anticancer activity.1 It is cytotoxic to A2780 ovarian cancer cells and carboplatin-resistant A2780 (A2780/CP70) cells (IC50s = 7.3 and <1 μM, respectively) and is 4.4-fold selective for A2780 cells over non-cancerous ARPE19 cells.

Uses

4-Dehydrowithaferin A is the analogue of withaferin A. Withaferin A is a withanolide isolated from Withania somnifera. 4-Dehydrowithaferin A has the potential for the research of multiple myeloma[1].

References

1. Perestelo, N.R., Llanos, G.G., Reyes, C.P., et al. Expanding the chemical space of withaferin A by incorporating silicon to improve its clinical potential on human ovarian carcinoma cells J. Med. Chem. 62(9),4571-4585(2019).

4-dehydrowithaferin A Preparation Products And Raw materials

Raw materials

Preparation Products

4-dehydrowithaferin A Suppliers

Global Suppliers ( 12)
Supplier Tel Email Country ProdList Advantage
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 400-920-5774 sales@glpbio.cn China 6705 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11123 58
Beijing Biocreative Technology Co., Ltd. 15522676233 3007606172@qq.com China 1246 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
Shanghai Yiyan Biotechnology Co. , Ltd. 021-69985186 13611928337 3427709316@qq.com China 7982 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11963 58

View Latest Price from 4-dehydrowithaferin A manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-oxo Withaferin A pictures 2026-05-11 4-oxo Withaferin A
6850-30-2
$316.00-1720.00 10g TargetMol Chemicals Inc.
4-dehydrowithaferin A 4-oxo Withaferin A Ergosta-2,24-dien-26-oic acid, 5,6-epoxy-22,27-dihydroxy-1,4-dioxo-, δ-lactone, (5β,6β,22R)- 6850-30-2