Steroid sulfatase/17β-HSD1-IN-3
- CAS No.
- 2990549-76-1
- Chemical Name:
- Steroid sulfatase/17β-HSD1-IN-3
- Synonyms
- Steroid sulfatase/17β-HSD1-IN-3;Sulfamic acid, 3-chloro-4-[5-[[methyl(2-methylphenyl)amino]carbonyl]-2-furanyl]phenyl ester
- CBNumber:
- CB113259630
- Molecular Formula:
- C19H17ClN2O5S
- Molecular Weight:
- 420.87
- MDL Number:
- MOL File:
- 2990549-76-1.mol
- MSDS File:
- SDS
Steroid sulfatase/17β-HSD1-IN-3 Chemical Properties, Uses, Production
Uses
Steroid sulfatase/17β-HSD1-IN-3 (compound 19) is a dual inhibitor of steroid sulfatase (STS) and 17β-hydroxysteroid dehydrogenase type 1 (17β HSD1). Steroid sulfatase/17β-HSD1-IN-3 irreversibly inhibits hSTS activity with anIC50 value of 27 nM. Steroid sulfatase/17β-HSD1-IN-3 can be used in the study of endometriosis and other estrogen-dependent diseases[1].
References
[1] Abdelrahman Mohamed, et al. Dual Targeting of Steroid Sulfatase and 17β-Hydroxysteroid Dehydrogenase Type 1 by a Novel Drug-Prodrug Approach: A Potential Therapeutic Option for the Treatment of Endometriosis. J Med Chem. 2022 Aug 22. DOI:10.1021/acs.jmedchem.2c00589
Steroid sulfatase/17β-HSD1-IN-3 Preparation Products And Raw materials
Raw materials
Preparation Products
Steroid sulfatase/17β-HSD1-IN-3 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Beckham Medical Technology Co., Ltd | 13816613772 | huahero21@sina.com | China | 2994 | 55 |
| Jinan Jiuli Biotechnology Co. , Ltd. | 15865264761 | 486064515@qq.com | China | 5000 | 58 |
| Supplier | Advantage |
|---|---|
| Shanghai Beckham Medical Technology Co., Ltd | 55 |
| Jinan Jiuli Biotechnology Co. , Ltd. | 58 |
