ChemicalBook >> CAS DataBase List >>9H-Purine, 9-[5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-ribofuranosyl]-, tetrasodium salt

9H-Purine, 9-[5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-ribofuranosyl]-, tetrasodium salt

CAS No.
35892-95-6
Chemical Name:
9H-Purine, 9-[5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-ribofuranosyl]-, tetrasodium salt
Synonyms
Purine riboside-5'-O-triphosphate (sodium salt);9H-Purine, 9-[5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-ribofuranosyl]-, tetrasodium salt
CBNumber:
CB113571703
Molecular Formula:
C10H15N4O13P3.4Na
Molecular Weight:
0
MDL Number:
MOL File:
Mol file
MSDS File:
SDS
Last updated:2025-08-21 14:05:29
Product description Number Pack Size Price
Purine riboside-5''-O-triphosphate (sodium salt) ≥95% 38491 2.5mg $280

9H-Purine, 9-[5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-ribofuranosyl]-, tetrasodium salt Properties

solubility Water: Soluble

9H-Purine, 9-[5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-ribofuranosyl]-, tetrasodium salt price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 38491 Purine riboside-5''-O-triphosphate (sodium salt) ≥95% 35892-95-6 2.5mg $280 2026-04-30 Buy
Product number Packaging Price Buy
38491 2.5mg $280 Buy

9H-Purine, 9-[5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-ribofuranosyl]-, tetrasodium salt Chemical Properties,Uses,Production

Uses

Purine riboside-5'-O-triphosphate sodium, an active metabolite of Nebularine (HY-103694), acts as an inhibitor of DNA primase ATP and GTP polymerization activities, with IC50 values of 35 μM and 28 μM for the human enzyme, respectively. Purine riboside-5'-O-triphosphate sodium inhibits calmodulin-dependent protein kinase II (CaMKII) with a Ki value of 590 μM[1][2][3].

References

[1] Kozlowska M, et al. ATP depletion, purine riboside triphosphate accumulation and rat thymocyte death induced by purine riboside. Toxicol Lett. 1999;104(3):171-181. DOI:10.1016/s0378-4274(98)00369-5
[2] Moore CL, et al. Human DNA primase uses Watson-Crick hydrogen bonds to distinguish between correct and incorrect nucleoside triphosphates. Biochemistry. 2004;43(38):12367-12374. DOI:10.1021/bi0490791
[3] Kwiatkowski AP, et al. Mapping of the adenosine 5'-triphosphate binding site of type II calmodulin-dependent protein kinase. Biochemistry. 1987;26(24):7636-7640. DOI:10.1021/bi00398a016

9H-Purine, 9-[5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-ribofuranosyl]-, tetrasodium salt Preparation Products And Raw materials

Raw materials

Preparation Products

9H-Purine, 9-[5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-ribofuranosyl]-, tetrasodium salt Suppliers

Global( 3)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11963 58
Shanghai meikai technology co., ltd 021-68689288 15300790979 info@mkbio.com.cn China 9988 58
9H-Purine, 9-[5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-ribofuranosyl]-, tetrasodium salt Purine riboside-5'-O-triphosphate (sodium salt) 35892-95-6 C10H15N4O13P34Na