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2-Pyridylethylamine

2-Pyridylethylamine Structure
2-Pyridylethylamine structure
CAS No.
2706-56-1
Chemical Name:
2-Pyridylethylamine
Synonyms
2-(2-PYRIDYL)ETHYLAMINE;2-(2-AMINOETHYL)PYRIDINE;2-(PYRIDIN-2-YL)ETHANAMINE;lilly04432;Demethylbetahistine;2-PYRIDYLETHYLAMINE;RARECHEM AL BW 0258;2-aminoethylpyridine;2-Pyridineethanamine;2-pyridineethylamine
CBNumber:
CB1137534
Molecular Formula:
C7H10N2
Molecular Weight:
122.17
MDL Number:
MFCD00006367
MOL File:
2706-56-1.mol
MSDS File:
SDS
Last updated:2026-05-27 23:07:48
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2-Pyridylethylamine Properties

Melting point 198-200 °C(Solv: ethanol (64-17-5))
Boiling point 92-93 °C12 mm Hg(lit.)
Density 1.021 g/mL at 25 °C(lit.)
refractive index n20/D 1.536(lit.)
Flash point 213 °F
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
form Liquid
pka pK1: 4.24(+2);pK2: 9.78(+1) (25°C,μ=0.05)
Specific Gravity 1.021
color Clear colorless to yellow
Water Solubility Soluble in water (partly), and most common polar solvent. Insoluble in non-polar solvents, and oils.
Sensitive Air Sensitive
BRN 111208
InChI 1S/C7H10N2/c8-5-4-7-3-1-2-6-9-7/h1-3,6H,4-5,8H2
InChIKey XPQIPUZPSLAZDV-UHFFFAOYSA-N
SMILES NCCc1ccccn1
CAS DataBase Reference 2706-56-1(CAS DataBase Reference)
FDA UNII ATW1AH7OJ5
NIST Chemistry Reference 2-Pyridineethanamine(2706-56-1)
EPA Substance Registry System 2-Pyridineethanamine (2706-56-1)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs Respiratory system
PPE Eyeshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Codes  Xi
Risk Statements  36/37/38-34
Safety Statements  26-36-45-36/37/39
RIDADR  2735
WGK Germany  3
F  10-34
TSCA  TSCA listed
HazardClass  8
PackingGroup  III
HS Code  29333990
Storage Class 10 - Combustible liquids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
NFPA 704
1
3 0

2-Pyridylethylamine price More Price(66)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich A55306 2-(2-Pyridyl)ethylamine 95% 2706-56-1 1g $47.6 2026-04-30 Buy
Sigma-Aldrich A55306 2-(2-Pyridyl)ethylamine 95% 2706-56-1 10g $313 2026-04-30 Buy
TCI Chemical A1999 2-(2-Aminoethyl)pyridine >98.0%(GC)(T) 2706-56-1 5g $59 2026-04-30 Buy
TCI Chemical A1999 2-(2-Aminoethyl)pyridine >98.0%(GC)(T) 2706-56-1 25g $174 2026-04-30 Buy
Usbiological 258220 2-(2-Aminoethyl) pyridine Asreported 2706-56-1 10g $388 2026-06-03 Buy
Product number Packaging Price Buy
A55306 1g $47.6 Buy
A55306 10g $313 Buy
A1999 5g $59 Buy
A1999 25g $174 Buy
258220 10g $388 Buy

2-Pyridylethylamine Chemical Properties, Uses, Production

Synthesis

Synthesis of 2706-56-1

A solution of sodium borohydride (0.26 g, 7.00 mmol) in 30 mL of diethyl ether was added dropwise to a mixture of 2-(cyanomethyl)pyridine (0.80 g, 6.82 mmol) and AlCl3 (0.93 g, 7.00 mmol). The solution was stirred at room temperature for 6 hours. The solvent was removed, and the resulting mixture was extracted with hot isopropyl ether (3 x 30 mL). The organic layers were combined, and the solvent was removed under reduced pressure to give 2-Pyridylethylamine.

Chemical Properties

clear colorless to yellow liquid

Uses

2-(2-Aminoethyl)pyridine is used as active pharmaceutical ingredients.

Definition

ChEBI: An aminoalkylpyridine that is pyridine substituted by a ethanamino group at position 2.

Biological Activity

Low doses of histamine or H1R agonist 2-pyridylethylamine (2-PEA) into the knee-joint were found to decrease formalin-induced articular nociception in rats. The pharmacological blockade and neurotoxic ablation of cells expressing neuropeptide Y1 receptor (Y1R) in the spinal cord were able to prevent the antinociceptive effect produced by the intra-articular administration of the histamine H1 receptor (H1R) agonist, 2-pyridylethilamine (2-PEA), in the formalin-induced articular incapacitation in rats[1].

References

[1] Eduardo Souza-Silva. “Intra-articular injection of 2-pyridylethylamine produces spinal NPY-mediated antinociception in the formalin-induced rat knee-joint pain model.” Brain Research 1735 (2020): Article 146757.

2-Pyridylethylamine synthesis

26510-52-1
2706-56-1
Synthesis of 2-Pyridylethylamine from Ethyl picolinoylacetate

2-Pyridylethylamine Preparation Products And Raw materials

Raw materials

2-Pyridineethanamine, N-[2-(2-pyridinyl)ethyl]- Carbamic acid, [2-(2-pyridyl)ethyl]-, Me ester (4CI) 3-(2-Pyridyl)propanamide 2-Cyanoethylpyridine 2-Hydroxy-2-pyridyl ethylamine
Mitomycin A 2-(2-Bromoethyl)pyridine 2-amino-1-(2-pyridinyl)Ethanone 3-Pyridin-2-yl-propionic acid H2SO4 Ethyl picolinoylacetate
2-Pyridinepropanoic acid, Methyl ester 2-Vinylpyridine

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Preparation Products

N1-(2,4-Dimethoxybenzyl)-N2-(2-pyridin-2-yl)ethyl)oxalamide 2-Pyridylacetonitrile N-(2-(Pyridin-2-yl)ethyl)acetamide

2-Pyridylethylamine Suppliers

Global Suppliers ( 331)
Supplier Tel Email Country ProdList Advantage
Hengshui Rayson Chemical Technology Co. , Ltd. 0318-8888981 13785822979 1532555757@qq.com China 18 58
Pushan Industry (Shaanxi) Co., Ltd. 029-81310890 18165209495 2929288192@qq.com China 9949 58
WEIFANG CYANOCHEM CO; LTD. 0571-85220831 13188860031 476521632@qq.com China 297 58
Xi 'an billiton biological technology co., LTD 029-88764766 wang.yali@xatuochao.com China 521 58
Xi'an Qingxiang Biotechnology Co., Ltd 029-18192656670 18192656670 2557411153@qq.com China 189 58
XIANAONARUNNEWMATERIALCo.,Ltd 029-81509060 13629280593 2074901304@qq.com China 185 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
Supplier Advantage
Hengshui Rayson Chemical Technology Co. , Ltd. 58
Pushan Industry (Shaanxi) Co., Ltd. 58
WEIFANG CYANOCHEM CO; LTD. 58
Xi 'an billiton biological technology co., LTD 58
Xi'an Qingxiang Biotechnology Co., Ltd 58
XIANAONARUNNEWMATERIALCo.,Ltd 58
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
3B Pharmachem (Wuhan) International Co.,Ltd. 69
Alfa Aesar 84

View Latest Price from 2-Pyridylethylamine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Pyridylethylamine pictures 2026-06-30 2-Pyridylethylamine
2706-56-1
 1KG 98.0% 10000KGS Shaanxi Dideu New Materials Co. Ltd
2-Pyridylethylamine pictures 2025-05-12 2-Pyridylethylamine
2706-56-1
 1kg 99% GC 5-10 MTs PUSHAN INDUSTRIAL (SHAANXI) CO.,LTD
2-Pyridylethylamine pictures 2025-04-04 2-Pyridylethylamine
2706-56-1
 1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.

2-Pyridylethylamine Spectrum

2-Pyridylethylamine(2706-56-1)MS2-Pyridylethylamine(2706-56-1)1HNMR2-Pyridylethylamine(2706-56-1)13CNMR2-Pyridylethylamine(2706-56-1)IR12-Pyridylethylamine(2706-56-1)Raman

2706-56-1 (2-Pyridylethylamine) Related Search:

2-(2-Aminoethylamino)ethanol Hydroxyethyl Cellulose Pyridine N-Aminoethylpiperazine Chromium picolinate
Diethylamine 2,6-Lutidine Ethyl cellulose Sulfasalazine Ethylamine
2-Chloro-3-cyanopyridine Ethyl maltol Triethylamine Betahistine dihydrochloride 3-Pyridineethaneamine
N,N-Diethyl-N-[2-(2-pyridyl)ethyl]amine Betahistine N-ethylpyridine-2-ethylamine

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RARECHEM AL BW 0258 2-PYRIDYLETHYLAMINE 2-Pyridineethanamine 2-PYRIDIN-2-YL-ETHYLAMINE 2-aminoethylpyridine Betahistine Impurity 11 2-(2-Aminoethyl)pyridine 98% 2-(2-Pyridinyl)ethanamine 2-(beta-Aminoethyl)pyridine alpha-Pyridylethylamine Demethylbetahistine lilly04432 Pyridine, 2-(2-aminoethyl)- 2-pyridineethylamine 2-(2-PYRIDYL)ETHYLAMINE 95+% 2-Pyridin-2-ylethanamin 2-(2-Aminoethyl)pyridine ,98% 2-(2-Pyridyl)ethanamine Pyridine-2-ethanamine 2-(2-Aminoethyl)pyridine,95% 2-(2-Pyridyl)ethylaMine 95% .alpha.-(2-Aminoethyl)pyridine 2-(2-AMinoethyl)pyridine, 95% 10GR 2-(2-AMinoethyl)pyridine, 95% 1GR (2-pyridin-2-ylethyl)amine(SALTDATA: FREE) 2-(2-Aminoethyl)pyridine > 2-Pyridylethylamine ISO 9001：2015 REACH 2-Pyridineethanamine (9CI, ACI) 1,3-dimethyl-26-nitrosourea 2-(Pyridin-2-yl)ethamine 2-(PYRIDIN-2-YL)ETHANAMINE 2-(2-AMINOETHYL)PYRIDINE 2-(2-PYRIDYL)ETHYLAMINE 2,5-Bis(2,2,2-trifluoroethoxy)benzoic aci 2706-56-1 Building Blocks C7 and C8 Heterocyclic Building Blocks Pyridines Pyridine