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2-Chloro-3-cyanopyridine

2-Chloro-3-cyanopyridine structure

CAS No.: 6602-54-6

Chemical Name:: 2-Chloro-3-cyanopyridine

Synonyms: 2-CHLORONICOTINONITRILE;2-Chloro-3-cyanopyri;2-CHLORONICOTINITRILE;3-cyano-2-chloropyridine;2-CHLORO-3-PYRIDINECARBONITRILE;NSC 73287;AKOS 93614;RARECHEM AH CK 0066;2-Chloronictinonitril;2-Chloronicotinotrile

CBNumber:: CB2360357

Molecular Formula:: C6H3ClN2

Molecular Weight:: 138.55

MDL Number:: MFCD00014628

MOL File:: 6602-54-6.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 00:19:48

Product description	Number	Pack Size	Price
2-Chloro-3-pyridinecarbonitrile 98%	535338	25g	$64.2
2-Chloro-3-pyridinecarbonitrile 98%	535338	500g	$261
2-Chloro-3-cyanopyridine >97.0%(GC)	C1369	25g	$28
2-Chloro-3-cyanopyridine >97.0%(GC)	C1369	500g	$329
2-Chloro-3-cyanopyridine ≥99.5%(HPLC)	27382	25G	$20
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2-Chloro-3-cyanopyridine Properties

Melting point	104-107 °C(lit.)
Boiling point	112°C 1mm
Density	1.3185 (rough estimate)
refractive index	1.4877 (estimate)
Flash point	112°C/1mm
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
form	Crystalline Powder or Flakes
pka	-2.17±0.10(Predicted)
color	White to off-white
BRN	115772
InChI	InChI=1S/C6H3ClN2/c7-6-5(4-8)2-1-3-9-6/h1-3H
InChIKey	JAUPUQRPBNDMDT-UHFFFAOYSA-N
SMILES	C1(Cl)=NC=CC=C1C#N
CAS DataBase Reference	6602-54-6(CAS DataBase Reference)
FDA UNII	2GQP44MUH2
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302+H312+H332-H315-H319-H335

Precautionary statements

P261-P280-P301+P312-P302+P352+P312-P304+P340+P312-P305+P351+P338

target organs

Respiratory system

PPE

dust mask type N95 (US), Eyeshields, Gloves

Hazard Codes

Xn,T,Xi

Risk Statements

20/21/22-36/37/38

Safety Statements

26-36-36/37/39

RIDADR

UN 3439 6.1/PG 3

WGK Germany

Hazard Note

Toxic/Irritant

HazardClass

6.1

PackingGroup

III

HS Code

29333990

Storage Class

6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects

Hazard Classifications

Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

Limited Quantities

5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)

Excepted Quantities

Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)

NFPA 704

	0
2		0

2-Chloro-3-cyanopyridine price More Price(72)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	535338	2-Chloro-3-pyridinecarbonitrile 98%	6602-54-6	25g	$64.2	2026-04-30	Buy
Sigma-Aldrich	535338	2-Chloro-3-pyridinecarbonitrile 98%	6602-54-6	500g	$261	2026-04-30	Buy
TCI Chemical	C1369	2-Chloro-3-cyanopyridine >97.0%(GC)	6602-54-6	25g	$28	2026-04-30	Buy
TCI Chemical	C1369	2-Chloro-3-cyanopyridine >97.0%(GC)	6602-54-6	500g	$329	2026-04-30	Buy
Chem-Impex	27382	2-Chloro-3-cyanopyridine ≥99.5%(HPLC)	6602-54-6	25G	$20	2026-05-19	Buy

Product number	Packaging	Price	Buy
535338	25g	$64.2	Buy
535338	500g	$261	Buy
C1369	25g	$28	Buy
C1369	500g	$329	Buy
27382	25G	$20	Buy

2-Chloro-3-cyanopyridine Chemical Properties,Uses,Production

Chemical Properties

white to light yellow crystal powder

Uses

2-Chloro-3-cyanopyridine (cas# 6602-54-6) is a compound useful in organic synthesis.

Reactions

2-Chloro-3-cyanopyridine is sensitive to oxidizing agents, it can undergo reduction and condensation reactions.

Hazard

2-Chloro-3-cyanopyridine has acute toxicity (Oral) and acute toxicity (Inhalation). It causes skin irritation and serious eye irritation.

Synthesis

2-Chloro-3-cyanopyridine is synthesized from 3-cyanopyridine. First, 3-cyanopyridine is treated with 28-31% H2O2 solution. After standing, the mixture is evaporated to yield nicotinamide-N-oxide. This oxide is then reacted with POCl3 at 35-80C. Additional POCl3 is added, and the mixture stands to form the chlorination solution. This solution undergoes reduced-pressure distillation. It is then cooled, and cold water is added. Filtration yields a solid phase. The solid is dissolved in a methanol-water system. Activated carbon is added for decolorization, followed by filtration. The filtrate is evaporated until crystals precipitate. Cooling gives the recrystallized product, which is finally dried under vacuum.

2-Chloro-3-cyanopyridine Preparation Products And Raw materials

Raw materials

2-Chloro-3-pyridinecarboxaldehyde 4-Chloro-3-cyanopyridine 2-Chloronicotinamide 3-Cyanopyridine

Preparation Products

ISOXAZOLO[5,4-B]PYRIDIN-3-YLAMINE 1-METHYL-1H-PYRAZOLO[3,4-B]PYRIDIN-3-YLAMINE 2-Chloro-5-hydroxymethylpyridine Furo[2,3-b]pyridine-2-carboxylic acid, 3-amino-, ethyl ester (9CI) Mirtazapine

4-Chlorothieno[3,2-d]pyrimidine 2-Aminonicotinic acid 1-(3-Cyanopyridyl-2)-2-Phenyl-4-Methylpyperazine METHYL 3-AMINOTHIENO[2,3-B]PYRIDINE-2-CARBOXYLATE 1-(3-Carboxypyrid-2-yl)-2-phenyl-4-methyl-piperazine

2-Hydroxynicotinic acid 2-chloro-5-cyanopyridine

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2-Chloro-3-cyanopyridine Suppliers

Global( 589)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	+8615350571055	Sibel@chuanghaibio.com	China	8738	58
Hebei Chuanghai Biotechnology Co,.LTD	+86-86-13131129325 +8613131129325	sales1@chuanghaibio.com	China	5231	58
Anhui Ruihan Technology Co., Ltd	+8617756083858	daisy@anhuiruihan.com	China	973	58
airuikechemical co., ltd.	+86-18353166132	sales02@airuikechemical.com	China	983	58
Hebei Zhuanglai Chemical Trading Co.,Ltd	+8613343047651	admin@zlchemi.com	China	3692	58
Capot Chemical Co.,Ltd.	+8613336195806	sales@capot.com	China	29640	60
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21588	55
Chembon Pharmaceutical Co., Ltd.	+86-28-8425-2981		CHINA	722	55
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29815	58
NINGBO INNO PHARMCHEM CO., LTD.	13867897135	sales@nbinno.com	CHINA	923	58

Supplier	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	58
Hebei Chuanghai Biotechnology Co,.LTD	58
Anhui Ruihan Technology Co., Ltd	58
airuikechemical co., ltd.	58
Hebei Zhuanglai Chemical Trading Co.,Ltd	58
Capot Chemical Co.,Ltd.	60
Henan Tianfu Chemical Co.,Ltd.	55
Chembon Pharmaceutical Co., Ltd.	55
career henan chemical co	58
NINGBO INNO PHARMCHEM CO., LTD.	58

View Lastest Price from 2-Chloro-3-cyanopyridine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-05-28	2-Chloro-3-cyanopyridine 6602-54-6			0.99		RongNa Biotechnology Co.,Ltd
2026-05-28	2-Chloro-3-cyanopyridine 6602-54-6	US $0.00 / KG	25KG	98%min	30tons/month	WUHAN FORTUNA CHEMICAL CO., LTD
2026-05-28	2-Chloro-3-cyanopyridine 6602-54-6	US $12.00 / KG	1KG	99.%	10 ton	Hebei Chuanghai Biotechnology Co,.LTD

2-Chloro-3-cyanopyridine
6602-54-6
0.99
RongNa Biotechnology Co.,Ltd

2-Chloro-3-cyanopyridine
6602-54-6
US $0.00 / KG
98%min
WUHAN FORTUNA CHEMICAL CO., LTD

2-Chloro-3-cyanopyridine
6602-54-6
US $12.00 / KG
99.%
Hebei Chuanghai Biotechnology Co,.LTD

2-Chloro-3-cyanopyridine Spectrum

2-Chloro-3-cyanopyridine(6602-54-6)MS 2-Chloro-3-cyanopyridine(6602-54-6)¹HNMR 2-Chloro-3-cyanopyridine(6602-54-6)¹³CNMR 2-Chloro-3-cyanopyridine(6602-54-6)IR1 2-Chloro-3-cyanopyridine(6602-54-6)IR2

6602-54-6(2-Chloro-3-cyanopyridine)Related Search:

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2-CHLOROPYRIDINE-3-CARBONITRILE 2-CHLORONICOTINITRILE 2-CHLORONICOTINONITRILE RARECHEM AH CK 0066 2-Chloro-3-cyanopyridine 97% 2-Chloronicotinonitrile (2-Chloro-3-cyano pyridine) 2-CHLORO-3-CYANO PYRIDINE 2-CHLORONICOTINONITRILE 2-CHLORO-3-CYANO-PYRIDINE, 2-CHLORONICTINONITRIL 2-Chloronictinonitril 2-CHLORONICOTINONITRILE ( CNN ) 3-cyano-2-chloropyridine 2-CHLORO-3-PYRIDINECARBONITRILE 2-CHLORO-3-CYANOPYRIDINE 2- chloro -3- cyanpyridine 2-Chloronicotinonitrile ,98% 2-Chloro-3-cyanopyridine,99% 2-Chloro-3-pyridinecarbonitrile, 97+% 2 - chloro sMoke nitrile 2-Chloro-3-cyanopyridine,98% 2-CHLORONICOTINONITRILE6602-54-6 2-Chloro-3-pyridinecarbonitrile 98% 2-Chloronicotinoitrile 2-Chloro-3-cyanopyridine≥ 99.5% (HPLC) 2-Chloronictinonitrile 2-Chloro-3-pyridinecarbonitrile ,98% 2-Chloro-3-pyridinecarbonitrile,2-Chloronicotinonitrile 2-Chloro-3-cyanopyri NSC 73287 2-Chloronicotinotrile 2-Chloro-3-cyanopyridine, 2-Chloropyridine-3-carbonitrile 2-Chloronicotinonitrile 97% AKOS 93614 3-PYRIDINECARBONITRILE, 2-CHLORO- 2-Chloro-3-cyanopyridine > 2-Chlor-3-cyanopyridine oro-3-pyridinecarbonitriL 2-Chloro-3-cyanopyridine ISO 9001：2015 REACH 2-Chloropyridine-3-carbonitrile (2-Chloronicotinonitrile) 2-Chlornicotinonitril Mirtazapine 2-Chloro nicotinitrile 2-chloro-3-cyno pyridine 6602-54-6 6606-54-6 C6H3N2Cl Pyridines Heterocyclic Building Blocks Halogenated Heterocycles Halopyridines Chloropyridines HETERO CHLORIDE Building Blocks pyridine series Amines Aromatics Heterocycles cyanide| alkyl chloride Chloropyridines Halopyridines