3-Bromo-4-tert-butylbenzoicacid
- CAS No.
- 38473-89-1
- Chemical Name:
- 3-Bromo-4-tert-butylbenzoicacid
- Synonyms
- 3-Bromo-4-(tert-butyl);3-Bromo-4-tert-butylbenzoicacid;3-BroMo-4-tert-butylbenzoicbacid;3-bromo-4-tert-butylbenzenemacetic acid;3-Bromo-4-(1,1-dimethylethyl)-benzoic acid;Benzoic acid, 3-bromo-4-(1,1-dimethylethyl)-
- CBNumber:
- CB11415167
- Molecular Formula:
- C11H13BrO2
- Molecular Weight:
- 257.12
- MDL Number:
- MOL File:
- 38473-89-1.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501 |
| HS Code | 2916399090 |
3-Bromo-4-tert-butylbenzoicacid price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR62202 | 3-Bromo-4-(tert-butyl)benzoic acid 95% | 38473-89-1 | 100mg | $105 | 2026-06-04 | Buy |
| Apolloscientific | OR62202 | 3-Bromo-4-(tert-butyl)benzoic acid 95% | 38473-89-1 | 250mg | $177 | 2026-06-04 | Buy |
| Apolloscientific | OR62202 | 3-Bromo-4-(tert-butyl)benzoic acid 95% | 38473-89-1 | 1g | $505 | 2026-06-04 | Buy |
| Apolloscientific | OR62202 | 3-Bromo-4-(tert-butyl)benzoic acid 95% | 38473-89-1 | 5g | $1298 | 2026-06-04 | Buy |
| Apolloscientific | OR62202 | 3-Bromo-4-(tert-butyl)benzoic acid 95% | 38473-89-1 | 10g | $2125 | 2026-06-04 | Buy |
3-Bromo-4-tert-butylbenzoicacid Chemical Properties, Uses, Production
Synthesis
98-73-7
38473-89-1
4-tert-butylbenzoic acid (500 mg, 2.8 mmol) was dissolved in acetic acid (11 mL), nitric acid (1.7 mL) and bromine (114 μL, 5.9 mmol) were added with rapid stirring. Subsequently, a solution of silver nitrate (1.01 g, 5.9 mmol) in water (5 mL) was slowly added to the reaction system, at which point a thick yellow precipitate was observed to form. After addition of additional acetic acid (2 mL), the reaction mixture was heated to reflux for 1 hour. Upon completion of the reaction, the reaction solution was filtered while hot and water was added dropwise to the filtrate until a white solid precipitated. The solid was collected, air dried and purified by recrystallization from acetic acid to give finally 3-bromo-4-tert-butylbenzoic acid as a white solid (263 mg, 36% yield). The product was characterized by 1H NMR (CDCl3, 300 MHz): δ 1.85 (s, 9H, (CH3)3), 7.86 (d, 1H, J = 8.5 Hz, ArH), 8.26 (dd, 1H, J = 2.0, 8.5 Hz, ArH), 8.62 (d, 1H, J = 2.0 Hz, ArH).
References
[1] Patent: WO2012/4567, 2012, A2. Location in patent: Page/Page column 91
[2] Australian Journal of Chemistry, 1990, vol. 43, # 5, p. 807 - 814
[3] Patent: WO2010/142956, 2010, A2. Location in patent: Page/Page column 28-29
[4] Journal of the Chemical Society, 1958, p. 120,126
3-Bromo-4-tert-butylbenzoicacid Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chembest Research Laboratories Limited | 021-20908456 | sales@BioChemBest.com | China | 5996 | 61 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Tianjin heowns Biochemical Technology Co., Ltd. | 400 638 7771 | sales@heowns.com | China | 14412 | 57 |
| Nanjing Norris-Pharm Technology Co., Ltd | 13901585132 | sales@norris-pharm.com | China | 8869 | 55 |
| Acesys Pharmatech | 18860950986 | tangmanman@zenjipharma.com | China | 1731 | 55 |
| Shanghai HuanChuan Industry Co.,Ltd. | 021-61478794 | sales@hcshhai.com | China | 9781 | 50 |
| SuZhou ShiYa Biopharmaceuticals, Inc. | 0512-0512-52358471 17715136450 | sales@shiyabiopharm.com | China | 9814 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Cochemical Ltd. | 029-86115547 17791676824 | sales@cochemical.com | China | 6746 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29626 | 60 |
