Ecdysoside B
- CAS No.
- 1887196-18-0
- Chemical Name:
- Ecdysoside B
- Synonyms
- Ecdysoside B;Pregna-5,14-dien-18-oic acid, 3-[(O-2,6-dideoxy-3-O-methyl-β-D-arabino-hexopyranosyl-(1→4)-O-2,6-dideoxy-3-O-methyl-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-3-O-methyl-β-D-ribo-hexopyranosyl)oxy]-20-hydroxy-16-oxo-, γ-lactone, (3β,20R)-
- CBNumber:
- CB114255602
- Molecular Formula:
- C42H62O13
- Molecular Weight:
- 774.94
- MDL Number:
- MOL File:
- 1887196-18-0.mol
Ecdysoside B Chemical Properties, Uses, Production
Uses
Ecdysoside B (compound 6b) is a pregnanoside compound isolated from the plant Ecdysanthera rosea. Ecdysoside B and its derivatives and isomers shows anticancer, immunosuppressive and anti-inflammatory activities. Ecdysoside B shows cytotoxicity to a variety of human tumor cell lines, including PANC-1 (human pancreatic cancer cells), A375 (human melanoma cells) and U87 (brain glioma U87 cells). Ecdysoside B can be used for research in the areas of cancer, immunomodulation and anti-inflammato[1].
References
[1] Zhang Z, et al. Merging total synthesis and NMR technology for deciphering the realistic structure of natural 2, 6-dideoxyglycosides[J]. Science Advances, 2024, 10(15): eadn1305. DOI:10.1126/sciadv.adn1305
