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CCT070535

CCT070535 structure

CAS No.: 485319-41-3

Chemical Name:: CCT070535

Synonyms: CCT070535;Pyrimido[1,2-b]pyridazin-5-ium, 7-chloro-1-(4-chlorophenyl)-1,2-dihydro-4-hydroxy-2-oxo-3-(phenylmethyl)-, inner salt

CBNumber:: CB114907912

Molecular Formula:: C20H13Cl2N3O2

Molecular Weight:: 398.24

MDL Number:

MOL File:: 485319-41-3.mol

Last updated:2025-11-14 08:07:06

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CCT070535 Properties

pka	4.500±1.00(predicted)

CCT070535 Chemical Properties, Uses, Production

Uses

CCT070535 blocks TCF-dependent transcription at the TCF level, with GI50 values of 17.6 μM, 11.1 μM, 11.8 μM and 13.4 μM in HT29 (APC mutant), HCT116 (oncogenic β-catenin), SW480 (APC mutant) and SNU475 (Axin mutant) cells, respectively[1].

References

[1] Kenneth Ewan, et al. A useful approach to identify novel small-molecule inhibitors of Wnt-dependent transcription. Cancer Res. 2010 Jul 15;70(14):5963-73. DOI:10.1158/0008-5472.CAN-10-1028

CCT070535 Preparation Products And Raw materials

Raw materials

Preparation Products

CCT070535 Suppliers

Global Suppliers ( 1)

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	29874	58

Supplier	Advantage
TargetMol Chemicals Inc.	58

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PYRVINIUM PAMOATE

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CCT070535 Pyrimido[1,2-b]pyridazin-5-ium, 7-chloro-1-(4-chlorophenyl)-1,2-dihydro-4-hydroxy-2-oxo-3-(phenylmethyl)-, inner salt 485319-41-3