DIMETHIRIMOL
- CAS No.
- 5221-53-4
- Chemical Name:
- DIMETHIRIMOL
- Synonyms
- PP675;melkeb;MILCURB;Midinol;NSC 263490;methyrimol;imethirimol;Dimethrimol;DIMETHIRIMOL;'LGC' (1633)
- CBNumber:
- CB1166516
- Molecular Formula:
- C11H19N3O
- Molecular Weight:
- 209.29
- MDL Number:
- MFCD00129666
- MOL File:
- 5221-53-4.mol
| Melting point | 103℃ |
|---|---|
| Boiling point | 348.66°C (rough estimate) |
| Density | 1.0465 (rough estimate) |
| vapor pressure | 1.5 x 10-3 Pa at 30 °C |
| refractive index | 1.5700 (estimate) |
| storage temp. | 0-6°C |
| pka | 5 |
| Water Solubility | 1.2 g l-1 (25 °C) |
| Henry's Law Constant | 2.3×1010 mol/(m3Pa) at 25℃, MacBean (2012) |
| InChI | InChI=1S/C11H19N3O/c1-5-6-7-9-8(2)12-11(14(3)4)13-10(9)15/h5-7H2,1-4H3,(H,12,13,15) |
| InChIKey | CJHXCRMKMMBYJQ-UHFFFAOYSA-N |
| SMILES | C1(N(C)C)=NC(C)=C(CCCC)C(=O)N1 |
| FDA UNII | 1V1RC2A67P |
| EPA Substance Registry System | Dimethirimol (5221-53-4) |
DIMETHIRIMOL price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | FAA22153 | Dimethrimol | 5221-53-4 | 5mg | $946.05 | 2026-06-04 | Buy |
| Biosynth | FAA22153 | Dimethrimol | 5221-53-4 | 10mg | $1316.2 | 2026-06-04 | Buy |
| Biosynth | FAA22153 | Dimethrimol | 5221-53-4 | 25mg | $2468 | 2026-06-04 | Buy |
| Biosynth | FAA22153 | Dimethrimol | 5221-53-4 | 50mg | $3948.5 | 2026-06-04 | Buy |
| TRC | D461523 | Dimethrimol | 5221-53-4 | 10mg | $1320 | 2021-12-16 | Buy |
DIMETHIRIMOL Chemical Properties, Uses, Production
Description
Dimethirimol is a systemic, eradicant fungicide. It has a high aqueous solubility and is quite volatile. Based on its chemical properties, it may leach to groundwater. It can be persistent in soil systems. Dimethirimol has a low mammalian toxicity. It is moderately toxic to birds and fish.
Chemical Properties
Pure product is white needle crystal, odorless. m.p.102℃, vapor pressure 1.46×10-3Pa (30℃), solubility at 25℃: chloroform 1200g/L, xylene 360g/L, ethanol 65g/L, propanol 45g/L, water 1.2g/L. Stable to acid, alkali, and heat, and non-corrosive to metal.
Uses
Dimethrimolis a fungicide used initially to prevent powdery mildew and other fungal infections or crops. Pesticide.
Uses
Fungicide.
Uses
Dimethirimol is a systemic fungicide that provides both protective and curative control of powdery mildew (Sphaeratheca fulginea) in cucurbits. Other uses include tobacco, tomatoes and ornamentals.
Definition
ChEBI: A member of the class of aminopyrimidines that is 2-dimethylaminopyrimidine carrying methyl, butyl and hydroxy substituents at posiitons 4, 5 and 6 respectively. A fungicide first marketed in 1970, and used particularly in glasshouses to control powdery mi dew, it is no longer approved for use within the European Union.
Production Methods
The commercial production of dimethirimol involves a multi-step process. It starts with the condensation of ethyl acetoacetate and butylamine to form an intermediate, followed by cyclisation with guanidine or a dimethylguanidine derivative in the presence of a base, such as sodium ethoxide, in an alcoholic solvent under controlled temperature to yield the pyrimidine ring structure. The crude dimethirimol is purified through filtration, washing, and recrystallisation to achieve high purity.
Mechanism of action
Systemic, ergosterol biosynthesis inhibitor. Nucleic acid synthesis - adenosin-deaminase.
Metabolic pathway
Information presented in this summary is abstracted from unpublished data in the 1971 ICI dimethirimol petition submitted to the Canadian authority. Dimethirimol is rapidly metabolised in both plants and animals. Primary metabolic reactions in soils, plants and animals are N-dealkylation, hydroxylation of the butyl group and the direct conjugation of dimethirimol in plants (glucosides) and animals (glucuronides). Metabolic pathways are shown in Scheme 1.
Degradation
Dimethirimol (1) is stable to heat and in acid and alkahe solutions. It is decomposed rather rapidly in aqueous solution when exposed to sunlight with an observed DT50 of 7 days.
Pesticide Type
Fungicide
DIMETHIRIMOL Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Changzhou Extraordinary Pharmatech co., LTD. | 0519-82111935 15195055733 | info@feifanchem.com | China | 737 | 58 |
| Sichuan Kulinan Technology Co., Ltd | 400-1166-196 18981987031 | cdhxsj@163.com | China | 11674 | 57 |
| Chengdu Ai Keda Chemical Technology Co., Ltd. | 4008-755-333 18080918076 | 800078821@qq.com | China | 9706 | 55 |
| The future of Shanghai Industrial Co., Ltd. | 021-61552785 | sales@shshiji.com | China | 9531 | 55 |
| Alta Scientific Co., Ltd. | 022-6537-8550 15522853686 | sales@altasci.com.cn | China | 4508 | 55 |
| Shandong Xiya Chemical Co., Ltd. | 4009903999 13395398332 | sales@xiyashiji.com | China | 20788 | 60 |
| Shandong Ono Chemical Co., Ltd. | 0539-6362799 20） | China | 10007 | 58 | |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 | sales@rrkchem.com | China | 57336 | 58 |
| HUNAN CHEMFISH SCIENTIFIC CO.,LTD | 0731-85567275 19313119732 | sales@chemfish.com | China | 7781 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +86-15350571055 | Sibel@chuanghaibio.com | China | 8737 | 58 |
View Latest Price from DIMETHIRIMOL manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-03-20 | DIMETHIRIMOL
5221-53-4
|
$9.90 | 1KG | 99% | 5tons | Hebei Chuanghai Biotechnology Co., Ltd |
-
- DIMETHIRIMOL
5221-53-4
- $9.90
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
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