3-ACETYL-1-(P-TOLYLSULFONYL)PYRROLE
- CAS No.
- 106058-85-9
- Chemical Name:
- 3-ACETYL-1-(P-TOLYLSULFONYL)PYRROLE
- Synonyms
- 3-ACETYL-N-TOSYLPYRROLE;3-ACETYL-1-TOSYLPYRROLE;1-TOSYL-3-ACETYLPYRROLE;1-(1-Tosyl-1H-pyrrol-3-yl)ethanone;3-ACETYL-1-(P-TOLYLSULFONYL)PYRROLE;1-(4-Tolylsulfonyl)-3-acetylpyrrole;3-acetyl-N-p-toluenesulfonylpyrrole;1-(1-tosyl-1h-pyrrol-3-yl)ethan-1-one;1-[1-(4-methylphenyl)sulfonyl-3-pyrrolyl]ethanone;1-(1-methylbenzenesulfonyl-1H-pyridine-3-yl)ethylone
- CBNumber:
- CB1195154
- Molecular Formula:
- C13H13NO3S
- Molecular Weight:
- 263.31
- MDL Number:
- MFCD00143087
- MOL File:
- 106058-85-9.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 1-TOSYL-3-ACETYLPYRROLE 97% | 66766 | 1G | $18 |
| 1-TOSYL-3-ACETYLPYRROLE 97% | 66766 | 5G | $45 |
| 1-TOSYL-3-ACETYLPYRROLE 97% | 66766 | 25G | $145 |
| 3-Acetyl-1-tosylpyrrole | GEA05885 | 0.25g | $250 |
| 3-Acetyl-1-tosylpyrrole | GEA05885 | 2.5g | $855.5 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319 |
| Precautionary statements | P261-P305+P351+P338 |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36/37/39 |
| HS Code | 2933998090 |
3-ACETYL-1-(P-TOLYLSULFONYL)PYRROLE price More Price(45)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| AstaTech | 66766 | 1-TOSYL-3-ACETYLPYRROLE 97% | 106058-85-9 | 1G | $18 | 2026-04-30 | Buy |
| AstaTech | 66766 | 1-TOSYL-3-ACETYLPYRROLE 97% | 106058-85-9 | 5G | $45 | 2026-04-30 | Buy |
| AstaTech | 66766 | 1-TOSYL-3-ACETYLPYRROLE 97% | 106058-85-9 | 25G | $145 | 2026-04-30 | Buy |
| Biosynth | GEA05885 | 3-Acetyl-1-tosylpyrrole | 106058-85-9 | 0.25g | $250 | 2026-06-04 | Buy |
| Biosynth | GEA05885 | 3-Acetyl-1-tosylpyrrole | 106058-85-9 | 2.5g | $855.5 | 2026-06-04 | Buy |
3-ACETYL-1-(P-TOLYLSULFONYL)PYRROLE Chemical Properties,Uses,Production
Synthesis
17639-64-4
108-24-7
106058-85-9
GENERAL STEPS: Acetic anhydride (0.44 mL, 4.7 mmol) was slowly added dropwise to a solution of dichloromethane (5.22 mL) containing aluminum chloride (896 mg, 6.7 mmol) at room temperature. After stirring the reaction mixture for 10 minutes, a solution of N-tosylpyrrole (400 mg, 1.81 mmol) in dichloromethane (0.9 mL) was added dropwise. Stirring of the reaction mixture was continued for 2 hours. Upon completion of the reaction, the mixture was poured into an ice-water mixture. The organic phase was separated and the aqueous phase was extracted with dichloromethane. The organic phases were combined, washed with 1N NaOH aqueous solution and dried over anhydrous sodium sulfate. After filtration, the solvent was evaporated to obtain the crude product. The crude product was washed with methanol and further purified to give 1-(1-toluenesulfonyl-1H-pyrrol-3-yl)ethanone (470 mg, 1.78 mmol, 99% yield) as a pure solid. Thin layer chromatography (TLC) analysis showed an Rf value of 0.5 (unfolding agent: hexane/ethyl acetate, 6/4). The structure of the product was confirmed by 1H NMR spectroscopy [24].
References
[1] Journal of Heterocyclic Chemistry, 2009, vol. 46, # 6, p. 1285 - 1295
[2] European Journal of Medicinal Chemistry, 2012, vol. 57, p. 391 - 397
[3] Patent: US2006/189555, 2006, A1. Location in patent: Page/Page column 10
[4] European Journal of Organic Chemistry, 2018, vol. 2018, # 1, p. 60 - 77
[5] Journal of Organic Chemistry, 1993, vol. 58, # 27, p. 7899 - 7902
3-ACETYL-1-(P-TOLYLSULFONYL)PYRROLE Preparation Products And Raw materials
Raw materials
Preparation Products
3-ACETYL-1-(P-TOLYLSULFONYL)PYRROLE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +86-13203830695 | laboratory@coreychem.com | China | 30224 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| DAYANG CHEM (HANGZHOU) CO.,LTD | +86-88938639 +86-17705817739 | info@dycnchem.com | China | 53803 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131956 | 58 |
| Shanghai Sinch Parmaceuticals Tech. Co. Ltd. | +86-21-54098501 | sales@sinch.com.cn | China | 11598 | 64 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40228 | 62 |
| Energy Chemical | 021-021-58432009 400-005-6266 | sales8178@energy-chemical.com | China | 44878 | 61 |
