1-Methylindole-3-carboxaldehyde
- CAS No.
- 19012-03-4
- Chemical Name:
- 1-Methylindole-3-carboxaldehyde
- Synonyms
- 1-METHYL-1H-INDOLE-3-CARBALDEHYDE;3-formyl-1-methylindole;NSC 83042;AKOS JY2082515;RARECHEM AH BS 0121;TIMTEC-BB SBB010057;N-Methyl-3-formylindole;ASINEX-REAG BAS 12967420;N-methyl-3-carboxaldehyde;1 METHYLINDOLE-3-ALDEHYDE
- CBNumber:
- CB1201057
- Molecular Formula:
- C10H9NO
- Molecular Weight:
- 159.18
- MDL Number:
- MFCD00014570
- MOL File:
- 19012-03-4.mol
- MSDS File:
- SDS
| Melting point | 70-72 °C (lit.) |
|---|---|
| Boiling point | 186-189 °C(Press: 3-4 Torr) |
| Density | 1.10±0.1 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| form | Crystalline Powder and Chunks |
| color | Light yellow to orange or brown |
| Water Solubility | Insoluble in water. |
| Sensitive | Air Sensitive |
| BRN | 121302 |
| CAS DataBase Reference | 19012-03-4(CAS DataBase Reference) |
| FDA UNII | Z612E3VMZ5 |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29339900 | |||||||||
| NFPA 704 |
|
1-Methylindole-3-carboxaldehyde price More Price(31)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 357987 | 1-Methylindole-3-carboxaldehyde 97% | 19012-03-4 | 5g | $74.5 | 2025-07-31 | Buy |
| Sigma-Aldrich | 357987 | 1-Methylindole-3-carboxaldehyde 97% | 19012-03-4 | 25g | $515 | 2023-06-20 | Buy |
| TCI Chemical | M1520 | 1-Methyl-1H-indole-3-carbaldehyde min. 98.0 % | 19012-03-4 | 5G | $68 | 2025-07-31 | Buy |
| TCI Chemical | M1520 | 1-Methyl-1H-indole-3-carbaldehyde min. 98.0 % | 19012-03-4 | 25G | $205 | 2025-07-31 | Buy |
| SynQuest Laboratories | 4H15-1-0J | 1-Methyl-1H-indole-3-carboxaldehyde 98% | 19012-03-4 | 5G | $80 | 2021-12-16 | Buy |
1-Methylindole-3-carboxaldehyde Chemical Properties,Uses,Production
Chemical Properties
light yellow to orange or brown crystalline powder
Uses
Reactant for preparation of nitroolefins and β-nitroalcohols via microwave- or ultrasound-assisted Henry reactions Reactant for synthesis of quinolinones via three-component Ugi reaction Reactant for synthesis of α-ketoamides as inhibitors of Dengue virus protease with antiviral activity in cell-culture Reactant for preparation of thiazolopyrimidinones as inhibitors of Bcl-2 proteins Reactant for preparation of vinylindoles via Peterson olefination or olefination with Nysted reagent Reactant for preparation of indolyl alkenes from microwave-enhanced Knoevenagel condensation as antibacterial agents.
Uses
1-Methylindole-3-carboxaldehyde is used as a reactant for preparation of nitroolefins and β-nitroalcohols via microwave- or ultrasound-assisted Henry reactions, reactant for synthesis of quinolinones via three-component Ugi reaction, reactant for synthesis of α-ketoamides as inhibitors of Dengue virus protease with antiviral activity in cell-culture, reactant for preparation of thiazolopyrimidinones as inhibitors of Bcl-2 proteins, reactant for preparation of vinylindoles via Peterson olefination or olefination with Nysted reagent, reactant for preparation of indolyl alkenes from microwave-enhanced Knoevenagel condensation as antibacterial agents 1-Methylindole-3-carboxaldehyde may be used in the synthesis of (Z)-3-(1-methyl-1H-indol-3-yl)-2-(thiophen-3-yl)acrylonitrile, via base-catalyzed condensation with thiophene-3-acetonitrile. It was also used in the preparation of monomer, required for the synthesis of poly(3-vinyl-1-methylindole).
Synthesis Reference(s)
Tetrahedron, 49, p. 4015, 1993 DOI: 10.1016/S0040-4020(01)89915-4
Synthesis, p. 396, 1987 DOI: 10.1055/s-1987-27960
General Description
1-Methylindole-3-carboxaldehyde is a heterocyclic indole aldehyde. 1-Methylindole-3-carboxaldehyde on condensation with 2-hydroxybenzohydrazide yields Schiff base.
1-Methylindole-3-carboxaldehyde Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29855 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49730 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-0519-85551759 +8613506123987 | marketing1@neostarunited.com | China | 8829 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 21063 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52846 | 58 |
| sgtlifesciences pvt ltd | +8617013299288 | dj@sgtlifesciences.com | China | 12373 | 58 |
View Lastest Price from 1-Methylindole-3-carboxaldehyde manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-08-25 | 1-Methylindole-3-carboxaldehyde
19012-03-4
|
US $1.00 / KG | 1KG | 99 | 100T | Henan Xiangtong Chemical Co., Ltd. | |
 |
2021-08-12 | 1-Methylindole-3-carboxaldehyde
19012-03-4
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd | |
 |
2019-07-06 | 1-Methylindole-3-carboxaldehyde
19012-03-4
|
US $8.80 / KG | 1KG | 97%-99% | 100kg | Career Henan Chemical Co |
-
- 1-Methylindole-3-carboxaldehyde
19012-03-4
- US $1.00 / KG
- 99
- Henan Xiangtong Chemical Co., Ltd.
-
- 1-Methylindole-3-carboxaldehyde
19012-03-4
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- 1-Methylindole-3-carboxaldehyde
19012-03-4
- US $8.80 / KG
- 97%-99%
- Career Henan Chemical Co
