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3-Trimethylsilylpropynal

3-Trimethylsilylpropynal Structure
3-Trimethylsilylpropynal structure
CAS No.
2975-46-4
Chemical Name:
3-Trimethylsilylpropynal
Synonyms
3-(triMethylsilyl)propiolaldehyde;DK722;DKFELEX0187;)-2-propynaL;Trimethylsilylpropynal;(Trimethylsilyl)propynal;3-Trimethylsilylpropynol;3-Trimethylsilylpropynal;Trimethylsilanyl-propynal;3-Trimethylsilylprop-2-Ynal
CBNumber:
CB4288965
Molecular Formula:
C6H10OSi
Molecular Weight:
126.23
MDL Number:
MFCD01103709
MOL File:
2975-46-4.mol
MSDS File:
SDS
Last updated:2026-09-12 18:52:44
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3-Trimethylsilylpropynal Properties

Melting point 195 °C
Boiling point 52 °C
Density 0.854 g/mL at 25 °C
refractive index n20/D 1.444
Flash point >25°C
storage temp. 2-8°C
form Liquid
Specific Gravity 0.86
color Colorless to yellow
Sensitive Air & Moisture Sensitive
Hydrolytic Sensitivity 4: no reaction with water under neutral conditions
InChI InChI=1S/C6H10OSi/c1-8(2,3)6-4-5-7/h5H,1-3H3
InChIKey LJRWLSKYGWLYIM-UHFFFAOYSA-N
SMILES C(=O)C#C[Si](C)(C)C
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Flame (GHS02)Exclamation Mark (GHS07)
GHS02,GHS07
Signal word  Warning
Hazard statements  H226-H315-H319-H335
Precautionary statements  P210-P302+P352-P305+P351+P338
target organs Respiratory system
PPE Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Codes  Xi
Risk Statements  10-36/37/38
Safety Statements  16-36/37/39-36/37-26
RIDADR  1993
WGK Germany  3
TSCA  No
HazardClass  3
PackingGroup  II
HS Code  29319090
Storage Class 3 - Flammable liquids
Hazard Classifications Eye Irrit. 2
Flam. Liq. 3
Skin Irrit. 2
STOT SE 3
Limited Quantities 5.0 L (1.3 gallons) (liquid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)
NFPA 704
2
2 0

3-Trimethylsilylpropynal price More Price(38)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 687170 3-(Trimethylsilyl)-2-propynal 97% 2975-46-4 1g $40 2023-06-20 Buy
TCI Chemical T2907 3-Trimethylsilylpropynal >97.0%(GC) 2975-46-4 1g $152 2026-04-30 Buy
TCI Chemical T2907 3-Trimethylsilylpropynal >97.0%(GC) 2975-46-4 5g $453 2026-04-30 Buy
Biosynth FT165825 3-(Trimethylsilyl)-2-propynal 2975-46-4 2g $150 2026-06-04 Buy
Biosynth FT165825 3-(Trimethylsilyl)-2-propynal 2975-46-4 5g $259.15 2026-06-04 Buy
Product number Packaging Price Buy
687170 1g $40 Buy
T2907 1g $152 Buy
T2907 5g $453 Buy
FT165825 2g $150 Buy
FT165825 5g $259.15 Buy

3-Trimethylsilylpropynal Chemical Properties, Uses, Production

Uses

3-Trimethylsilylpropynal acts as an important organic intermediate. It is used in agrochemicals, pharmaceuticals and dyestuff field. Further, it is used in the preparation of [3-(trimethylsilyl)-2-propinyliden]-malononitrile.

Synthesis

N,N-Dimethylformamide

68-12-2

Trimethylsilylacetylene

1066-54-2

3-TRIMETHYLSILYLPROPYNAL

2975-46-4

Steps for the synthesis of 3-trimethylsilylpropynal: 1. A solution of trimethylsilylacetylene (5.0 mL, 36.10 mmol) in THF (25.0 mL) was added dropwise to a solution of EtMgBr in THF (1 M, 44.0 mL, 44.0 mmol) under nitrogen protection, and the reaction temperature was maintained at 10-150°C. 2. After the dropwise addition, the reaction mixture was stirred at room temperature for 1 hour. 3. A solution of Et2O (20.0 mL) in DMF (10.0 mL, 123.0 mmol) was slowly added to the reaction system at -25 °C, and the addition time was controlled to be within 30 min. 4. The resulting white suspension was gradually warmed to room temperature and stirring was continued for 1 hour. 5. The reaction mixture was heated to 30 °C and maintained for 15 minutes. 6. The reaction solution was cooled to 0 °C and poured into 5% H2SO4 solution. 7. The aqueous layer was separated and extracted three times with Et2O. 8. Combine the organic layers, wash with saturated aqueous NH4Cl solution and dry with anhydrous Na2SO4. 9. Concentrate under pressure to remove the solvent and obtain the crude product. 10. purification of the crude product by ball-to-ball distillation (20 mbar, room temperature) afforded 3-trimethylsilylpropynal (2.255 g, 49% yield). Product characterization data: 1H NMR: δ 9.15 (s, 1H), 0.25 (s, 9H). 13C NMR: δ 176.7, 103.0, 102.3, 0.88.

References

[1] Tetrahedron Letters, 1995, vol. 36, # 3, p. 401 - 404
[2] Angewandte Chemie - International Edition, 2008, vol. 47, # 6, p. 1130 - 1133
[3] Tetrahedron, 2002, vol. 58, # 12, p. 2415 - 2422
[4] Arkivoc, 2012, vol. 2012, # 7, p. 253 - 273
[5] Patent: WO2009/141781, 2009, A1. Location in patent: Page/Page column 18

3-Trimethylsilylpropynal synthesis

1066-54-2
2975-46-4
Synthesis of 3-Trimethylsilylpropynal from Trimethylsilylacetylene

3-Trimethylsilylpropynal Preparation Products And Raw materials

Raw materials

Tetrahydro-2-[[3-(trimethylsilyl)-2-propyn-1-yl]oxy]-2H-Pyran 1-Hexyl-1h-indole-3-carboxaldehyde 3-Trimethylsilyl-2-propyn-1-ol 1-Benzyl-1H-indole-3-carbaldehyde CHEMBRDG-BB 5100225
Methyl 3-(trimethylsilyl)propiolate Propargyloxytrimethylsilane Lithium (trimethylsilyl)acetylide 1-trimethylsilyloxy-3-trimethylsilylprop-2-yne 1-Methylindole-3-carboxaldehyde
Trimethylsilylacetylene

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Preparation Products

3-(DiethylaMino)acrylaldehyde

3-Trimethylsilylpropynal Suppliers

Global Suppliers ( 165)
Supplier Tel Email Country ProdList Advantage
Shanghai Guijing New Material Technology Co., Ltd. 18616507986 2433448178@qq.com China 703 58
Bengbu Chen Yixin Materials Technology Co., Ltd. 15655950695 15655950695 1608252589@qq.com China 498 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Beijing HwrkChemical Technology Co., Ltd 89508211 18501085097 sales.bj@hwrkchemical.com China 9407 55
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Jia Xing Isenchem Co.,Ltd 0573-85285100 18627885956 isenchem@163.com China 9389 66
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Supplier Advantage
Shanghai Guijing New Material Technology Co., Ltd. 58
Bengbu Chen Yixin Materials Technology Co., Ltd. 58
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
Alfa Aesar 84
TCI (Shanghai) Development Co., Ltd. 81
Beijing HwrkChemical Technology Co., Ltd 55
Energy Chemical 61
Jia Xing Isenchem Co.,Ltd 66
Shanghai Hanhong Scientific Co.,Ltd. 64

View Latest Price from 3-Trimethylsilylpropynal manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3-TRIMETHYLSILYLPROPYNAL pictures 2026-03-20 3-TRIMETHYLSILYLPROPYNAL
2975-46-4
 1KG 99% 20 mt Hebei Chuanghai Biotechnology Co., Ltd
3-TRIMETHYLSILYLPROPYNAL pictures 2025-04-15 3-TRIMETHYLSILYLPROPYNAL
2975-46-4
 $10.00 1kg 99% 20ton Hebei Zhuanglai Chemical Trading Co.,Ltd
3-TRIMETHYLSILYLPROPYNAL pictures 2019-07-06 3-TRIMETHYLSILYLPROPYNAL
2975-46-4
 $2.00 1KG 99% Career Henan Chemical Co

3-Trimethylsilylpropynal Spectrum

3-TRIMETHYLSILYLPROPYNAL(2975-46-4)1HNMR

2975-46-4 (3-Trimethylsilylpropynal) Related Search:

(tert-Butyldimethylsilyloxy)acetaldehyde 4-(Trimethylsilyl)-3-butyn-2-one Methyl 3-(trimethylsilyl)propiolate 3-Trimethylsilylpropynal Propyne
3-(Trimethylsilyl)propiolic acid PROPYNAL 3-(Triethylsilyl)-2-propynal Trimethylsilyl(trimethylsilyl)propynoate 1-Phenyl-4-trimethylsilanyl-but-3-yn-2-one
1-Chloro-4-trimethylsilanyl-but-3-yn-2-one Ethyl 3-(trimethylsilyl)propiolate 4-Chloro-1-trimethylsilanyl-pent-1-yn-3-one 3-tert-Butyldimethylsilylpropynal 1-Cyclopropyl-3-trimethylsilanyl-propynone
4-Chloro-1-trimethylsilanyl-hex-1-yn-3-one 1-Bromo-1-phenyl-4-trimethylsilanyl-but-3-yn-2-one

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3-Trimethylsilylpropynol 3-(TRIMETHYLSILYL)-2-PROPYNAL 3-(TRIMETHYLSILYL)PROPARGYL ALDEHYDE 3-(Trimethylsilyl)-2-propynal 97% 3-Trimethylsilylprop-2-Ynal (Trimethylsilyl)propiolaldehyde (Trimethylsilyl)propynal Trimethylsilylpropynal 3-TriMethylsilylpropynal, 98.0%,(GC) 2-Propynal, 3-(trimethylsilyl)- )-2-propynaL Trimethylsilanyl-propynal DK722 DKFELEX0187 3-(triMethylsilyl)propiolaldehyde 3-Trimethylsilylpropynal 2975-46-4 CH33SiCCCHO C6H10OSi