DEATH RECEPTOR 4
- CAS No.
- Chemical Name:
- DEATH RECEPTOR 4
- Synonyms
- DR4;Apo2;DRB4;HLA-DR4B;HUMAN DR4;TNFRSF10A;DR beta 4;HUMAN APO2;HUMAN TNFRSF10A;DEATH RECEPTOR 4
- CBNumber:
- CB1208379
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD03792340
- MOL File:
- Mol file
| storage temp. | -20°C |
|---|---|
| form | lyophilized |
| color | white |
| biological source | human |
| NCI Dictionary of Cancer Terms | death receptor 4; DR4 |
| UNSPSC Code | 51111800 |
| NACRES | NA.77 |
DEATH RECEPTOR 4 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SRP3164 | sTRAIL Receptor-1 (DR4) human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture | 50μG | $369 | 2025-07-31 | Buy | |
| Usbiological | 579555 | TNFRSF10A PurifiedbyProteinGaffinitychromatography. | 50ug | $509 | 2026-06-03 | Buy | |
| Usbiological | 579555 | TNFRSF10A PurifiedbyProteinGaffinitychromatography. | 100ug | $708 | 2026-06-03 | Buy | |
| Usbiological | 313944 | DR4 Purifiedbyimmunoaffinitychromatography. | 50ug | $403 | 2026-06-03 | Buy | |
| Usbiological | 313944 | DR4 Purifiedbyimmunoaffinitychromatography. | 100ug | $531 | 2026-06-03 | Buy |
DEATH RECEPTOR 4 Chemical Properties, Uses, Production
Uses
Soluble tumor necrosis factor-related apoptosis-inducing ligand-receptor 1 (sTRAIL-R1) also known as DR4, is encoded by the gene mapped to human chromosome 8p21-22. Recombinant human soluble TRAIL Receptor-1/DR4 is a 22.7kDa protein (216 amino acid residues) consisting of the TNFR homologous, cysteine rich portion of the extracellular domain. TRAIL Receptor-1/DR4 and TRAIL Receptor-2/DR5 belong to the TNFR superfamily of transmembrane proteins. TRAIL-R1 contains a cytoplasmic "death domain," which can activate the cell′s apoptotic machinery. TRAIL Receptor-1/DR4 is activated by binding to either membrane anchored or soluble TRAIL/Apo2L.
Biological Activity
Soluble tumor necrosis factor-related apoptosis-inducing ligand-receptor 1 (sTRAIL-R1) interacts with tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and stimulate cell-death signaling pathway. Mutation of the sTRAIL-R1 gene is associated with the pathogenesis of non-Hodgkinμs lymphoma (NHL). In addition, variation of TRAIL-R1 also increases the risk of susceptibility to prostate cancer (PCa) in North Indian population.
DEATH RECEPTOR 4 Preparation Products And Raw materials
Raw materials
Preparation Products
DEATH RECEPTOR 4 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Wuhan Chemstan Biotechnology Co., Ltd. | 027-65317797 15926423062 | 422450190@qq.com | China | 10305 | 58 |
| Shanghai Bolsen Biotechnology Co., LTD | 021-67681877 13166061152 | bioesn@163.com | China | 9991 | 58 |
| Shanghai Huzhen Industrial Co., LTD | 021-60345367 13916550749 | sales@shzbio.com | China | 9965 | 58 |
| Shanghai Yubo Biotechnology Co., Ltd | 021-60514606 18321282235 | sale1@shybsw.net | China | 8165 | 58 |
| shlmai | 021-67680335 13052188602 | sale1@shlmai.net | China | 10000 | 58 |
| Shanghai Yaji Biotechnology Co., Ltd. | 021-34661276 15317085058 | 1278329642@qq.com | China | 6418 | 58 |
