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Spirolaxin

Spirolaxin Structure
Spirolaxin structure
CAS No.
126382-01-2
Chemical Name:
Spirolaxin
Synonyms
Spirolaxin;Spirolaxine;(3R)-5-Hydroxy-7-methoxy-3-[5-[(2R,5R,7R)-2-methyl-1,6-dioxaspiro[4.5]decane-7-yl]pentyl]isobenzofuran-1(3H)-one;1(3H)-Isobenzofuranone, 5-hydroxy-7-methoxy-3-[5-[(2R,5R,7R)-2-methyl-1,6-dioxaspiro[4.5]dec-7-yl]pentyl]-, (3R)-
CBNumber:
CB12240885
Molecular Formula:
C23H32O6
Molecular Weight:
404.5
MDL Number:
MOL File:
126382-01-2.mol
MSDS File:
SDS
Last updated:2026-07-24 20:02:53
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Spirolaxin Properties

Boiling point 600.884±55.00 °C(Press: 760.00 Torr)(predicted)
Density 1.222±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO
form A solid
pka 7.698±0.40(predicted)

Spirolaxin price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 22063 Spirolaxine ≥95% 126382-01-2 500μg $160 2026-04-30 Buy
Cayman Chemical 22063 Spirolaxine ≥95% 126382-01-2 2.5mg $758 2026-04-30 Buy
Biosynth BFA38201 Spirolaxine 126382-01-2 1mg $644.66 2026-06-04 Buy
Biosynth BFA38201 Spirolaxine 126382-01-2 5mg $2095.15 2026-06-04 Buy
Biosynth BFA38201 Spirolaxine 126382-01-2 10mg $3352.3 2026-06-04 Buy
Product number Packaging Price Buy
22063 500μg $160 Buy
22063 2.5mg $758 Buy
BFA38201 1mg $644.66 Buy
BFA38201 5mg $2095.15 Buy
BFA38201 10mg $3352.3 Buy

Spirolaxin Chemical Properties, Uses, Production

Description

Spirolaxine is a long-chain phthalide produced by the fungus S. laxum that has antibacterial properties. Spirolaxine is a potent anti-H. pylori agent (MIC = 0.2 μg/cm3) with weak activity against E. coli. Spirolaxine (1-40 μM) inhibits proliferation of endothelial (BMEC, HUVEC) and tumor (LoVo, HL-60) cells in culture. B. megaterium and C. echinulate produce hydroxylated metabolites of spirolaxine when given spirolaxine as a substrate.

Uses

Spirolaxine is a bioactive undecaketide fungal metabolite found in Sporotrichum laxum ATCC 15155. Spirolaxine exhibits anti-Helicobacter pylori property.

IC 50

Microbial Metabolite

References

[1] ALBERTO ARNONE . Spirolaxine and sporotricale: Two long-chain phthalides produced by Sporotrichum laxum[J]. Phytochemistry, 1990, 29 2: Pages 613-616. DOI: 10.1016/0031-9422(90)85127-2
[2] De Souza, F.I., Zumiotti, A.V., and Da Silva, C.F. Neuregulins 1-α and 1-β on the regeneration the peripheral nerves[J]. Acta Ortop Bras.
[3] A. LEóN. Phthalides: Distribution in Nature, Chemical Reactivity, Synthesis, and Biological Activity.[J]. Progress in the chemistry of organic natural products, 2017, 26 1: 127-246. DOI: 10.1007/978-3-319-45618-8_2
[4] De Souza, F.I., Zumiotti, A.V., and Da Silva, C.F. Neuregulins 1-α and 1-β on the regeneration the peripheral nerves[J]. Acta Ortop Bras.
[5] GIANLUCA NASINI. Microbial Transformation of Spirolaxine, a Bioactive Undecaketide Fungal Metabolite from the Basidiomycete Sporotrichum laxum[J]. Chemistry & Biodiversity, 2007, 4 12: 2772-2779. DOI: 10.1002/cbdv.200790226

Spirolaxin Preparation Products And Raw materials

Raw materials

Preparation Products

Spirolaxin Suppliers

Global Suppliers ( 13)
Supplier Tel Email Country ProdList Advantage
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 400-920-5774 sales@glpbio.cn China 6705 58
BOC Sciences 16314854226; +8616314854226 inquiry@bocsci.com United States 19852 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Meng Cheng Technology (Shanghai) Co., LTD 400-820-6829 sales@mitachieve.com China 8857 58
Shanghai Saikerui Biotechnology Co. , Ltd. 021-58000709 13120558703 sales@scrbio.com China 9876 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11963 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
Shanghai Weiyite Biotechnology Co., Ltd 15317051735 zhaojing@wytsci.com China 10000 58
Supplier Advantage
Shanghai Hongye Biotechnology Co. Ltd 58
BOC Sciences 58
TargetMol Chemicals Inc. 58
Meng Cheng Technology (Shanghai) Co., LTD 58
Shanghai Saikerui Biotechnology Co. , Ltd. 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
TargetMol Chemicals Inc. 58
Shanghai Weiyite Biotechnology Co., Ltd 58

View Latest Price from Spirolaxin manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Spirolaxine pictures 2026-05-11 Spirolaxine
126382-01-2
 $1720.00 10g TargetMol Chemicals Inc.

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(3R)-5-Hydroxy-7-methoxy-3-[5-[(2R,5R,7R)-2-methyl-1,6-dioxaspiro[4.5]decane-7-yl]pentyl]isobenzofuran-1(3H)-one Spirolaxin Spirolaxine 1(3H)-Isobenzofuranone, 5-hydroxy-7-methoxy-3-[5-[(2R,5R,7R)-2-methyl-1,6-dioxaspiro[4.5]dec-7-yl]pentyl]-, (3R)- 126382-01-2