3-Methoxyazetidine hydrochloride
- CAS No.
- 148644-09-1
- Chemical Name:
- 3-Methoxyazetidine hydrochloride
- Synonyms
- 3-Methoxy-azetidine HCl;3-Methoxyazetidine hydroc...;3-METHOXY-AZETIDINE HYDROCHLORIDE;3-Methoxyazetidinehydrochloride,95%;Azetidine, 3-Methoxy-, hydrochloride;3-Azetidinyl methyl ether hydrochloride;3-methoxy-Azetidine hydrochloride (1:1);3-Methoxyazetidine hydrochloride - [M0107];3-METHOXY-AZETIDINE HYDROCHLORIDE, 97%min;Azetidine, 3-Methoxy- (hydrochloride)(1:1)
- CBNumber:
- CB1238893
- Molecular Formula:
- C4H10ClNO
- Molecular Weight:
- 123.58
- MDL Number:
- MFCD06804514
- MOL File:
- 148644-09-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Boiling point | 143-149℃ |
|---|---|
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| form | solid |
| color | White |
| InChI | InChI=1S/C4H9NO.ClH/c1-6-4-2-5-3-4;/h4-5H,2-3H2,1H3;1H |
| InChIKey | KSXGQRBTBLQJEF-UHFFFAOYSA-N |
| SMILES | C1C(OC)CN1.Cl |
| CAS DataBase Reference | 148644-09-1 |
| UNSPSC Code | 12352200 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Risk Statements | 41 | |||||||||
| Safety Statements | 26-39 | |||||||||
| WGK Germany | WGK 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 2933998090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
3-Methoxyazetidine hydrochloride price More Price(52)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | CDS006482 | 3-methoxyazetidine hydrochloride AldrichCPR | 50 mg | $77.9 | 2026-04-30 | Buy | |
| Usbiological | 284073 | 3-Methoxy-azetidine hydrochloride Asreported | 148644-09-1 | 500mg | $347 | 2026-06-03 | Buy |
| Usbiological | 284073 | 3-Methoxy-azetidine hydrochloride Asreported | 148644-09-1 | 1g | $625 | 2026-06-03 | Buy |
| Usbiological | 284073 | 3-Methoxy-azetidine hydrochloride Asreported | 148644-09-1 | 2g | $909 | 2026-06-03 | Buy |
| Usbiological | 284073 | 3-Methoxy-azetidine hydrochloride Asreported | 148644-09-1 | 5g | $1293 | 2026-06-03 | Buy |
3-Methoxyazetidine hydrochloride Chemical Properties, Uses, Production
Synthesis
Sodium hydride (60%, in mineral oil) (0.74 g, 18.5 mmol) was added to a solution of tert-butyl 3-hydroxy-azacyclobutane-1-carboxylic acid (0.8 g, 4.62 mmol) in THF (50 mL). The solution was stirred at 0 °C for 0.5 h, followed by the addition of methyl iodide (2.8 mL, 46.2 mmol). The reaction mixture was stirred overnight at room temperature. The reaction was quenched with water (50 mL) and extracted with EtOAc (30 mL × 3). The combined organic phases were dried over Na₂SO₄, filtered, and concentrated under vacuum to give compound 1-BOC-3-methoxyazacyclobutane (0.8 g, 93%) as an oil. Concentrated hydrochloric acid (5 mL) was added to a solution of compound 1-BOC-3-methoxyazacyclobutane (0.8 g, 4.29 mmol) in methanol (20 mL). The resulting solution was stirred at 25 °C for 16 h.
The reaction mixture was concentrated to dryness under vacuum to give 3-methoxy-azacyclobutane hydrochloride (0.48 g, 92%).
Uses
3-Methoxyazetidine hydrochloride is used in the preparation of isoxazole-thiazole derivatives as GABA A receptor inverse agonists for use in the treatment of cognitive disorders.
Uses
It is used in the preparation of isoxazole-thiazole derivatives as GABA. It is a receptor inverse agonists for use in the treatment of cognitive disorders.
3-Methoxyazetidine hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Anhui Leyong Biotechnology Co.,Ltd | 15055708011 | 2093564781@qq.com | China | 400 | 58 |
| Shengbaolai Biotechnology Co., Ltd | 027-86-027-59105235 15527244834 | shengblai@126.com | China | 488 | 58 |
| Beijing Whale Technology Corporation Ltd. | 010-83694934 13671295325 | sales@whalecorporation.com | China | 107 | 58 |
| Jinan New Synharmony PharmaTech Co., Ltd. | 13806405245 18560110739 | 1073692093@qq.com | China | 111 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Changzhou Huanling Chemical Co., Ltd. | 89803005 18206112582 | info@huanlingchem.com | China | 983 | 68 |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
View Latest Price from 3-Methoxyazetidine hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-05-23 | 3-methoxyazetidine hydrochloride
148644-09-1
|
$50.00 | 1kg | 99 | 5000 | Hebei Zhuanglai Chemical Trading Co Ltd | |
 |
2020-01-15 | 3-Methoxyazetidine hydrochloride
148644-09-1
|
$5.50 | 1IU | 98%min | 1kg-100kg | Career Henan Chemical Co |
-
- 3-methoxyazetidine hydrochloride
148644-09-1
- $50.00
- 99
- Hebei Zhuanglai Chemical Trading Co Ltd
-
- 3-Methoxyazetidine hydrochloride
148644-09-1
- $5.50
- 98%min
- Career Henan Chemical Co
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