ChemicalBook >> CAS DataBase List >>1-METHYL-5-NITRO-1H-INDAZOLE

1-METHYL-5-NITRO-1H-INDAZOLE

CAS No.
5228-49-9
Chemical Name:
1-METHYL-5-NITRO-1H-INDAZOLE
Synonyms
SW-35;SWF-35;1-METHYL-5-NITROINDAZOLE;1-METHYL-5-NITRO-1H-INDAZOLE;5-Nitro-1-methyl-1H-indazole;1H-Indazole, 1-methyl-5-nitro-;1-METHYL-5-NITRO-1H-INDAZOLE, 98+%;1-methyl-5-nitro-1H-indazole, 1-methyl-5-nitroindazole, 1-methyl-5-nitro-1H-indazole, 1-Methyl-5-nitro-1H-indazol, 1-methyl-5-nitro-indazole, 1-Methyl-5-nitro-indazol, 1-Methyl-5-nitroindazol
CBNumber:
CB1239421
Molecular Formula:
C8H7N3O2
Molecular Weight:
177.16
MDL Number:
MFCD01318163
MOL File:
5228-49-9.mol
Last updated:2025-07-24 18:13:50
Product description Number Pack Size Price
1-Methyl-5-nitro-1H-indazole M218795 500mg $75
1-Methyl-5-nitro-1H-indazole W6706 5g $161
1-Methyl-5-nitro-1H-indazole OR14146 250mg $15
1-Methyl-5-nitro-1H-indazole 4H54-1-V8 250mg $16
1-Methyl-5-nitro-1H-indazole OR14146 1g $28
More product size

1-METHYL-5-NITRO-1H-INDAZOLE Properties

Melting point 161-162°C
Boiling point 332.9±15.0 °C(Predicted)
Density 1.42±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
form solid
pka -0.82±0.30(Predicted)
color yellow
BRN 168080
CAS DataBase Reference 5228-49-9(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P301+P312+P330
Hazard Codes  Xi
Risk Statements  20/22-68
Safety Statements  22-36/37
RIDADR  2811
HazardClass  IRRITANT
PackingGroup  II
HS Code  2933998090
NFPA 704
1
0 0

1-METHYL-5-NITRO-1H-INDAZOLE price More Price(20)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC M218795 1-Methyl-5-nitro-1H-indazole 5228-49-9 500mg $75 2021-12-16 Buy
AK Scientific W6706 1-Methyl-5-nitro-1H-indazole 5228-49-9 5g $161 2021-12-16 Buy
Apolloscientific OR14146 1-Methyl-5-nitro-1H-indazole 5228-49-9 250mg $15 2021-12-16 Buy
SynQuest Laboratories 4H54-1-V8 1-Methyl-5-nitro-1H-indazole 5228-49-9 250mg $16 2021-12-16 Buy
Apolloscientific OR14146 1-Methyl-5-nitro-1H-indazole 5228-49-9 1g $28 2021-12-16 Buy
Product number Packaging Price Buy
M218795 500mg $75 Buy
W6706 5g $161 Buy
OR14146 250mg $15 Buy
4H54-1-V8 250mg $16 Buy
OR14146 1g $28 Buy

1-METHYL-5-NITRO-1H-INDAZOLE Chemical Properties,Uses,Production

Synthesis

5-Nitroindazole

5401-94-5

Iodomethane

74-88-4

2-METHYL-5-NITRO-2H-INDAZOLE

5228-48-8

1-METHYL-5-NITRO-1H-INDAZOLE

5228-49-9

GENERAL METHOD: Cesium carbonate (12.26 mmol) was added to a solution of 5-nitroindazole (6.13 mmol) in tetrahydrofuran (THF; 25 mL) at 0 °C. The reaction mixture was stirred at 0 °C for 15 min before iodomethane or allyl bromide (6.13 mmol) was added dropwise. The progress of the reaction was monitored by thin layer chromatography (TLC) until the starting material completely disappeared. After completion of the reaction, the mixture was concentrated. The crude product was dissolved in ethyl acetate (EtOAc; 50 mL), washed sequentially with water and brine, and the organic phase was dried over anhydrous magnesium sulfate (MgSO?). The solvent was removed by evaporation under reduced pressure, and the resulting residue was purified by silica gel column chromatography with ethyl acetate/hexane (3:7, v/v) as eluent to afford 1-alkyl-5-nitroindazole and 2-alkyl-5-nitroindazole, respectively.

References

[1] Synthetic Communications, 2015, vol. 45, # 17, p. 2005 - 2013
[2] Tetrahedron, 2008, vol. 64, # 28, p. 6711 - 6723
[3] Patent: US2014/371219, 2014, A1. Location in patent: Paragraph 0659; 0660; 0661
[4] Patent: WO2016/57834, 2016, A1. Location in patent: Paragraph 000406

1-METHYL-5-NITRO-1H-INDAZOLE Preparation Products And Raw materials

Global( 141)Suppliers
Supplier Tel Email Country ProdList Advantage
Accela ChemBio Inc.
+1-858-6993322 info@accelachem.com United States 21193 58
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49975 58
career henan chemical co
+86-0371-86658258 +8613203830695 factory@coreychem.com China 29799 58
Shaanxi Dideu Medichem Co. Ltd
+86-29-87569266 +86-17392581500 1015@dideu.com China 3965 58
Fuxin Pharmaceutical
+86-021-021-50872116 +8613122107989 contact@fuxinpharm.com China 10035 58
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34563 58
Blocksynth Pharmaceutical Technology Co.,Ltd
0086-19817745290; +8619817745290 bd@blocksynth.com China 5661 58
Hefei Hirisun Pharmatech Co., Ltd
+8615056975894 shawn@hirisunpharm.com CHINA 9911 58
Dayang Chem (Hangzhou) Co.,Ltd.
+86-0571-88938639 +8617705817739 info@dycnchem.com China 52846 58

View Lastest Price from 1-METHYL-5-NITRO-1H-INDAZOLE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1-METHYL-5-NITRO-1H-INDAZOLE pictures 2021-08-12 1-METHYL-5-NITRO-1H-INDAZOLE
5228-49-9
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
1-METHYL-5-NITRO-1H-INDAZOLE pictures 2019-12-25 1-METHYL-5-NITRO-1H-INDAZOLE
5228-49-9
US $0.10 / KG 1KG 95%-99% 1kg; 50kg; 500kg Career Henan Chemical Co

1-METHYL-5-NITRO-1H-INDAZOLE Spectrum

1-METHYL-5-NITROINDAZOLE 1-METHYL-5-NITRO-1H-INDAZOLE 1-methyl-5-nitro-1H-indazole, 1-methyl-5-nitroindazole, 1-methyl-5-nitro-1H-indazole, 1-Methyl-5-nitro-1H-indazol, 1-methyl-5-nitro-indazole, 1-Methyl-5-nitro-indazol, 1-Methyl-5-nitroindazol 1-METHYL-5-NITRO-1H-INDAZOLE, 98+% 5-Nitro-1-methyl-1H-indazole 1H-Indazole, 1-methyl-5-nitro- SWF-35 SW-35 5228-49-9 Indazoles