5-bromo-1H-indazole
- CAS No.
- 53857-57-1
- Chemical Name:
- 5-bromo-1H-indazole
- Synonyms
- 5-BROMO-1H-INDAZOLE;5-BROMOINDAZOLE;4-BROMOIMIDAZOLE;SW-4;SWF-4;5-Bromoindazole-2;5-Bromoindazole >1H-Indazole, 5-bromo-;5-Bromo-1H-indazole 97%;5-Bromo-1H-indazole ,98%
- CBNumber:
- CB2262387
- Molecular Formula:
- C7H5BrN2
- Molecular Weight:
- 197.03
- MDL Number:
- MFCD00839493
- MOL File:
- 53857-57-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 131-135 °C(lit.) |
|---|---|
| Boiling point | 333.8±15.0 °C(Predicted) |
| Density | 1.770±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | soluble in Methanol |
| form | powder to crystal |
| pka | 12.74±0.40(Predicted) |
| color | White to Light yellow to Light orange |
| InChI | InChI=1S/C7H5BrN2/c8-6-1-2-7-5(3-6)4-9-10-7/h1-4H,(H,9,10) |
| InChIKey | STVHMYNPQCLUNJ-UHFFFAOYSA-N |
| SMILES | N1C2=C(C=C(Br)C=C2)C=N1 |
| CAS DataBase Reference | 53857-57-1(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
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|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H318 | |||||||||
| Precautionary statements | P280-P301+P312+P330-P305+P351+P338+P310 | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | T,Xn | |||||||||
| Risk Statements | 25-36/37/38-22-41 | |||||||||
| Safety Statements | 26-36-36/37/39-22-39 | |||||||||
| RIDADR | UN 2811 6.1/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | NI3517450 | |||||||||
| Hazard Note | Harmful | |||||||||
| HS Code | 29339900 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Eye Dam. 1 |
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| NFPA 704 |
|
5-bromo-1H-indazole price More Price(79)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 702293 | 5-Bromo-1H-indazole 97% | 53857-57-1 | 1g | $63.8 | 2026-04-30 | Buy |
| TCI Chemical | B3785 | 5-Bromoindazole >97.0%(GC) | 53857-57-1 | 1g | $49 | 2026-04-30 | Buy |
| TCI Chemical | B3785 | 5-Bromoindazole >97.0%(GC) | 53857-57-1 | 5g | $192 | 2026-04-30 | Buy |
| Usbiological | 265687 | 5-Bromo-1H-indazole Asreported | 53857-57-1 | 1g | $349 | 2026-06-03 | Buy |
| Usbiological | 265687 | 5-Bromo-1H-indazole Asreported | 53857-57-1 | 2g | $506 | 2026-06-03 | Buy |
5-bromo-1H-indazole Chemical Properties, Uses, Production
Chemical Properties
White to light brown solid
Uses
5-bromo-1H-indazole (5-BIA) is an indazole compound that can be used as a raw material in organic synthesis for the preparation of compounds such as 5-Iodo-1H-indazole and 3,5-Dibromo-1H-indazole. 5-BIA and its derivatives (7-BIA) can also be used as a highly effective corrosion inhibitor for copper and the protective ability of 5-BIA is more prominent than that of 7-BIA. 5-BIA and its derivatives (7-BIA) can also be used as highly efficient corrosion inhibitors for copper, and 5-BIA has a more prominent protective ability than 7-BIA. 1.5 mM 5-BIA and 1.5 mM 7-BIA have corrosion inhibition efficiencies (ηE) as high as 97.1 % and 94.0 %, respectively[1].
Synthesis
In a dry 500 mL reaction flask, NaNO2 ( 3.89 g , 56.3 mmol) and water ( 10 m L ) were sequentially added to an acetic acid solution ( 300 mL ) of 4-bromo-o-toluidine ( 10.5 g , 56.3 mmol). The resulting reaction mixture was stirred at room temperature for 5 h. The progress of the reaction was monitored by TLC dot plate, and when the reaction was finished, the reaction mixture was concentrated directly under vacuum, and then the residue was diluted with ethyl acetate, and the ethyl acetate layer was washed sequentially with saturated aqueous NaHCO3 solution and brine. The organic layer was separated and dried over anhydrous Na2SO4, the desiccant was removed by filtration and the resulting filtrate was concentrated under vacuum. The residue was purified by silica gel column chromatography (0-50% ethyl acetate in n-hexane) to obtain 5-bromoindazole, note that if the product obtained by isolation is liquid, it can be solidified by adding n-hexane to it, shaking it and spinning it dry.
References
[1] JIE ZENG . Adsorption films based on indazole derivatives for application to protect Cu in sulfuric acid: Experimental and theoretical approaches[J]. Journal of the Taiwan Institute of Chemical Engineers, 2023. DOI:10.1016/j.jtice.2023.105134.
5-bromo-1H-indazole Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Changzhou Ucheml Medicine Co., Ltd. | 0519-86058959 13775231161 | sales@uchemi.cn | China | 301 | 50 |
| Nanjing Puxin Pharmaceutical Technology Co., Ltd | 17366295326 | puxinpharma_2017@126.com | China | 2444 | 58 |
| shanghai huiyu | 15380804498 | hj.yang@nstbio.com | China | 293 | 58 |
| Suzhou aihua pharmaceutical technology Co.,Ltd | 13814852116 13814852116 | 373953886@qq.com | China | 22 | 58 |
| Shanghai yirong biology science and technology co., ltd | 18049974220 | 3060526242@qq.com | China | 999 | 60 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Yangzhou Siyu Chemical Co.,Ltd. | 0514-87325867 | sales@siyuchem.com | China | 370 | 55 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Beijing HwrkChemical Technology Co., Ltd | 89508211 18501085097 | sales.bj@hwrkchemical.com | China | 9407 | 55 |
View Latest Price from 5-bromo-1H-indazole manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-03-20 | 5-Bromoindazole
53857-57-1
|
$10.00 | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2026-02-02 | 5-Bromoindazole
53857-57-1
|
$99.00-800.00 | 1g | 99% | 2000tons | Shaanxi Dideu Medichem Co. Ltd | |
 |
2025-04-04 | 5-Bromoindazole
53857-57-1
|
1KG | 98% | 1ton | Henan Aochuang Chemical Co.,Ltd. |
-
- 5-Bromoindazole
53857-57-1
- $10.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- 5-Bromoindazole
53857-57-1
- $99.00-800.00
- 99%
- Shaanxi Dideu Medichem Co. Ltd
-
- 5-Bromoindazole
53857-57-1
- 98%
- Henan Aochuang Chemical Co.,Ltd.
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