Boc-His(Tos)-Merrifield resin
- CAS No.
- 33018-91-6
- Chemical Name:
- Boc-His(Tos)-Merrifield resin
- Synonyms
- 2-ethylheptanedioate;MonoethylPimelate>BOC-HIS(TOS)-PAM RESIN;BOC-HIS(TOS)-BHA RESIN;BOC-HIS(TOS)-CMS RESIN;Ethyl hydrogen pimelate;Monoethyl Heptanedioate;BOC-HIS(TOS)-MBHA RESIN;pimelicacidmonethylester;BOC-HIS(TOS)-BHA PS RESIN
- CBNumber:
- CB1243129
- Molecular Formula:
- C9H16O4
- Molecular Weight:
- 188.22
- MDL Number:
- MFCD00014383
- MOL File:
- 33018-91-6.mol
- MSDS File:
- SDS
| Melting point | 10°C |
|---|---|
| Boiling point | 135-138°C 1mm |
| Density | 1.06 |
| refractive index | 1.4420 |
| Flash point | 135-138°C/1mm |
| storage temp. | Sealed in dry,2-8°C |
| pka | 4.74±0.10(Predicted) |
| form | powder to lump to clear liquid |
| color | White or Colorless to Almost white or Almost colorless |
| Water Solubility | Not miscible or difficult to mix with water. |
| BRN | 1774583 |
| InChI | InChI=1S/C9H16O4/c1-2-13-9(12)7-5-3-4-6-8(10)11/h2-7H2,1H3,(H,10,11) |
| InChIKey | NQYXFXWKKYGBNL-UHFFFAOYSA-N |
| SMILES | C(OCC)(=O)CCCCCC(O)=O |
| CAS DataBase Reference | 33018-91-6 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319 | |||||||||
| Precautionary statements | P264-P280a-P305+P351+P338-P321-P332+P313-P337+P313 | |||||||||
| Risk Statements | 36/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 2917.19.7050 | |||||||||
| NFPA 704 |
|
Boc-His(Tos)-Merrifield resin price More Price(28)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | P1244 | Monoethyl Pimelate >98.0%(GC) | 33018-91-6 | 5g | $62 | 2026-04-30 | Buy |
| TCI Chemical | P1244 | Monoethyl Pimelate >98.0%(GC) | 33018-91-6 | 25g | $171 | 2026-04-30 | Buy |
| Biosynth | IBA01891 | Monoethyl Pimelate | 33018-91-6 | 25g | $295 | 2026-06-04 | Buy |
| ChemScene | CS-W016803 | Monoethyl pimelate ≥98% | 33018-91-6 | 5g | $28 | 2026-06-04 | Buy |
| ChemScene | CS-W016803 | Monoethyl pimelate ≥98% | 33018-91-6 | 10g | $53 | 2026-06-04 | Buy |
Boc-His(Tos)-Merrifield resin Chemical Properties, Uses, Production
Uses
Ethyl hydrogen pimelate is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff fields.
Synthesis
2050-20-6
33018-91-6
3) Synthesis of 7-ethoxy-7-oxoheptanoic acid: potassium hydroxide (KOH, 16.8 g, 0.30 mol) was added to a solution of diethyl heptanedioate (65 g, 0.30 mol) in ethanol (400 mL). The reaction mixture was stirred at 80 °C for 24 h. After completion of the reaction, the solvent was removed by concentration under reduced pressure. The concentrated mixture was poured into water and the pH of the aqueous solution was adjusted with concentrated sulfuric acid (H2SO4) to 1. The aqueous phase was extracted and the organic solvent was removed to give the crude product. The crude product was purified by fast column chromatography (silica gel SiO2 as stationary phase, eluent ratio of ethanol:ethyl acetate=1:10), and finally 7-ethoxy-7-oxoheptanoic acid was obtained (38 g, 67% yield).
References
[1] Patent: US2014/256775, 2014, A1. Location in patent: Paragraph 0178; 0183; 0184
[2] Journal of Medicinal Chemistry, 2009, vol. 52, # 9, p. 2776 - 2785
[3] Bulletin de la Societe Chimique de France, 1910, vol. <4>7, p. 219
[4] Journal of the Chemical Society, 1901, vol. 79, p. 1192
[5] Bioorganic Chemistry, 1998, vol. 26, # 3, p. 157 - 168
Boc-His(Tos)-Merrifield resin Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Shanghai Sinch Parmaceuticals Tech. Co. Ltd. | +86-21-54098501 | sales@sinch.com.cn | China | 11592 | 64 |
| Syntechem Co.,Ltd | info@syntechem.com | China | 12973 | 57 | |
| ChemPep, Inc. | +1 (888) 615-9178 / (561) 791-8787 | service@chempep.com | United States | 2138 | 57 |
| Wuhan ariel chemical Co., LTD. | 18986259541 18986259541 | sales@3stc.com | China | 3828 | 58 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66113011 13913916777 | cfzhang@aikonchem.com | China | 19902 | 55 |
View Latest Price from Boc-His(Tos)-Merrifield resin manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-09 | Monoethyl pimelate
33018-91-6
|
$29.00 | 97.35% | 10g | TargetMol Chemicals Inc. | ||
 |
2025-04-04 | BOC-HIS(TOS)-MERRIFIELD RESIN
33018-91-6
|
1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | ||
 |
2022-09-27 | BOC-HIS(TOS)-MERRIFIELD RESIN
33018-91-6
|
1kg | 99% | 1000kg | henan kanbei chemical co.,ltd |
-
- Monoethyl pimelate
33018-91-6
- $29.00
- 97.35%
- TargetMol Chemicals Inc.
-
- BOC-HIS(TOS)-MERRIFIELD RESIN
33018-91-6
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- BOC-HIS(TOS)-MERRIFIELD RESIN
33018-91-6
- $0.00
- 99%
- henan kanbei chemical co.,ltd
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