ChemicalBook >> CAS DataBase List >>RO 0437626

RO 0437626

RO 0437626 structure

CAS No.: 134362-79-1

Chemical Name:: RO 0437626

Synonyms: RO 0437626;N-[(1R)-2-[[(1S,2R,3S)-1-(Cyclohexylmethyl)-3-cyclopropyl-2,3-dihydroxypropyl]amino]-2-oxo-1-(4-thiazolylmethyl)ethyl]-1H-benzimidazole-2-carboxamide;1H-Benzimidazole-2-carboxamide, N-[(1R)-2-[[(1S,2R,3S)-1-(cyclohexylmethyl)-3-cyclopropyl-2,3-dihydroxypropyl]amino]-2-oxo-1-(4-thiazolylmethyl)ethyl]-

CBNumber:: CB12458150

Molecular Formula:: C27H35N5O4S

Molecular Weight:: 525.66

MDL Number:: MFCD07363878

MOL File:: 134362-79-1.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-04-24 14:58:40

Request For Quotation

RO 0437626 Properties

storage temp.	Store at -20°C
solubility	Soluble to 100 mM in DMSO and to 100 mM in ethanol
form	Powder

RO 0437626 price More Price(10)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Usbiological	464771	Ro 0437626	134362-79-1	1mg	$482	2026-06-03	Buy
Usbiological	464771	Ro 0437626	134362-79-1	2.5mg	$814	2026-06-03	Buy
Usbiological	256471	Ro 0437626 Asreported	134362-79-1	1mg	$403	2026-06-03	Buy
Usbiological	256471	Ro 0437626 Asreported	134362-79-1	10mg	$616	2026-06-03	Buy
ApexBio Technology	B6964	Ro 0437626	134362-79-1	1mg	$246	2026-05-06	Buy

Product number	Packaging	Price	Buy
464771	1mg	$482	Buy
464771	2.5mg	$814	Buy
256471	1mg	$403	Buy
256471	10mg	$616	Buy
B6964	1mg	$246	Buy

RO 0437626 Chemical Properties, Uses, Production

Uses

Ro 0437626 is a P2X1 purinergic receptor antagonist.

Biological Activity

Selective P2X 1 purinergic receptor antagonist (IC 50 = 3 μ M) that displays > 30-fold selectivity over P2X 2 , P2X 3 and P2X 2/3 receptors (IC 50 > 100 μ M).

in vivo

Ro 0437626 (1 and 10 μmol/kg; i.v.) causes a reduction in postinfusion isovolumetric contractions^[3].

Animal Model:	Female rat (urethane-anaesthetized)^[3]
Dosage:	1 and 10 μmol/kg
Administration:	I.v.
Result:	Caused a reduction in postinfusion isovolumetric contractions.

RO 0437626 Preparation Products And Raw materials

Raw materials

Preparation Products

RO 0437626 Suppliers

Global Suppliers ( 26)

Supplier	Tel	Email	Country	ProdList	Advantage
3B Pharmachem (Wuhan) International Co.,Ltd.	18930552037	3bsc@sina.com	China	15813	69
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8435	60
Shanghai Han-Xiang Chemical Co., Ltd.	17754423994	candy@biochempartner.com	China	3057	58
TargetMol Chemicals Inc.	+1-781-999-5354; +1-00000000000	marketing@targetmol.com	United States	32431	58
MedBioPharmaceutical Technology Inc	021-69568360 18916172912	order@med-bio.cn	China	8137	58
TargetMol Chemicals Inc.	4008200310 15002144251	marketing@tsbiochem.com	China	24951	58
Chengdu Peter-like Biotechnology Co., Ltd.	028-81700200 13308200041	2851167782@qq.com	China	10763	58
Aladdin Scientific		tp@aladdinsci.com	United States	50068	58
Wuhan Topule Biopharmaceutical Co., Ltd	+86-18327326525	masar@topule.com	China	8433	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49709	58

Supplier	Advantage
3B Pharmachem (Wuhan) International Co.,Ltd.	69
EMMX Biotechnology LLC	60
Shanghai Han-Xiang Chemical Co., Ltd.	58
TargetMol Chemicals Inc.	58
MedBioPharmaceutical Technology Inc	58
TargetMol Chemicals Inc.	58
Chengdu Peter-like Biotechnology Co., Ltd.	58
Aladdin Scientific	58
Wuhan Topule Biopharmaceutical Co., Ltd	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	58

134362-79-1 (RO 0437626) Related Search:

1H-Imidazol-2-carboxamide RO 0437626 Ppads tetrasodium salt 1H-Naphtho[1,2-b][1,4]diazepine-2,4(3H,5H)-dione, 5-[3-(2,5-dihydro-5-thioxo-1,2,4-oxadiazol-3-yl)phenyl]-, sodium salt (1:1) N-[2-[[2-[(2-Hydroxyethyl)amino]ethyl]amino]-5-quinolinyl]-2-tricyclo[3.3.1.13,7]dec-1-ylacetamidedihydrochloride

2'- and 3'-O-(4-Benzoylbenzoyl)-adenosine 5'-triphosphate triethylammonium salt

1of2

RO 0437626 N-[(1R)-2-[[(1S,2R,3S)-1-(Cyclohexylmethyl)-3-cyclopropyl-2,3-dihydroxypropyl]amino]-2-oxo-1-(4-thiazolylmethyl)ethyl]-1H-benzimidazole-2-carboxamide 1H-Benzimidazole-2-carboxamide, N-[(1R)-2-[[(1S,2R,3S)-1-(cyclohexylmethyl)-3-cyclopropyl-2,3-dihydroxypropyl]amino]-2-oxo-1-(4-thiazolylmethyl)ethyl]- 134362-79-1 C27H35N5O4S