Methyl 2-amino-5-cyanobenzoate
- CAS No.
- 159847-81-1
- Chemical Name:
- Methyl 2-amino-5-cyanobenzoate
- Synonyms
- Methyl 2-amino-5-cyanobenzoate;2-Amino-5-cyanobenzoic acid methyl ester;Methyl 2-amino-5-cyanobenzoate≥ 97% (HPLC);Benzoic acid, 2-amino-5-cyano-, methyl ester
- CBNumber:
- CB12468704
- Molecular Formula:
- C9H8N2O2
- Molecular Weight:
- 176.17
- MDL Number:
- MFCD11041293
- MOL File:
- 159847-81-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H301-H312+H332-H315-H319-H335 |
| Precautionary statements | P260-P280-P301+P310 |
| HS Code | 2916399090 |
Methyl 2-amino-5-cyanobenzoate price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR400352 | Methyl 2-amino-5-cyanobenzoate 98% | 159847-81-1 | 100mg | $51 | 2026-06-04 | Buy |
| Apolloscientific | OR400352 | Methyl 2-amino-5-cyanobenzoate 98% | 159847-81-1 | 250mg | $62 | 2026-06-04 | Buy |
| Apolloscientific | OR400352 | Methyl 2-amino-5-cyanobenzoate 98% | 159847-81-1 | 1g | $96 | 2026-06-04 | Buy |
| Apolloscientific | OR400352 | Methyl 2-amino-5-cyanobenzoate 98% | 159847-81-1 | 5g | $398 | 2026-06-04 | Buy |
| Apolloscientific | OR400352 | Methyl 2-amino-5-cyanobenzoate 98% | 159847-81-1 | 25g | $1313 | 2026-06-04 | Buy |
Methyl 2-amino-5-cyanobenzoate Chemical Properties, Uses, Production
Chemical Properties
Pale yellow crystalline powder
Synthesis
544-92-3
52727-57-8
159847-81-1
A mixture of methyl 2-amino-5-bromobenzoate (50 g, 217 mmol) and cuprous cyanide (19.7 g, 220 mmol) was heated to reflux (ca. 200 °C) in 200 mL of N-methyl-2-pyrrolidinone and reacted overnight, followed by cooling to room temperature. The dark reaction mixture was slowly poured into 1800 mL of ether under vigorous stirring. The dark viscous oily material at the bottom was separated and discarded, and the upper turbid solution was washed sequentially with 200 mL of saturated saline, 200 mL of 1 M sodium hydroxide solution, and twice with 200 mL of saturated saline (total 2000 mL). The organic phase was dried over anhydrous sodium sulfate and concentrated to dryness under reduced pressure to give about 20 g of a yellow solid, methyl 2-amino-5-cyanobenzoate crude, in 52% yield.
References
[1] Patent: WO2005/9967, 2005, A2. Location in patent: Page/Page column 78-79
[2] Patent: WO2004/2940, 2004, A1. Location in patent: Page 41; 42
[3] Patent: WO2004/18414, 2004, A2. Location in patent: Page 58
Methyl 2-amino-5-cyanobenzoate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| shanghai aokchem co., ltd | 021-68712331 39130253 | aokchem@gmail.com | China | 332 | 58 |
| SynAsst Chemical. | 021-60343070 | China | 12731 | 55 | |
| Nanjing ShengSai Chemical Co., Ltd. | 025-85205967 13951876367 | shengsaichem@163.com | China | 818 | 58 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Shanghai HuanChuan Industry Co.,Ltd. | 021-61478794 | sales@hcshhai.com | China | 9781 | 50 |
| Cool Pharm, Ltd | 021-60455363 18019463053 | sales@coolpharm.com | China | 8455 | 58 |
| Changzhou Anxuan Chemical, Co., Ltd. | 13912302692 | sales@anxuanchem.com | China | 4824 | 58 |
| skychemical Co.Ltd | 021-20960837,QQ1332204249 | sales@skychemical.com | China | 3338 | 55 |
| ShangHai Siyan Biological Technology Co., Ltd. | 021-50908862，442785678，326799392 18721037013 | siyansales@126.com | China | 9612 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
