Choline tosylate
- CAS No.
- 55357-38-5
- Chemical Name:
- Choline tosylate
- Synonyms
- Choline p-toluenesulfonate;CHOLINE P-TOLUENESULFONATE SALT;2-Hydroxy-N,N,N-triMethylethanaMiniuM 4-Methylbenzenesulfonate;CHOLINE TOSYLATE;Choline toluenesulfonate;Choline 4-methylbenzenesulphonate salt;cholanparamethylbenzenesulfonylacidsalt;Choline 4-methylbenzenesulphonate salt 99%;(2-Hydroxyethyl)trimethylammonium toluene-4-sulfonate;(2-Hydroxyethyl)trimethylammonium toluene-4-sulphonate
- CBNumber:
- CB1254402
- Molecular Formula:
- C12H21NO4S
- Molecular Weight:
- 275.36
- MDL Number:
- MFCD00079051
- MOL File:
- 55357-38-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Choline p-Toluenesulfonate Salt | TRC-C433050-5G | 5g | $354 |
| Choline p-Toluenesulfonate Salt | TRC-C433050-10G | 10g | $523 |
| Choline tosylate | FCA35738 | 0.5g | $241.25 |
| Choline tosylate | FCA35738 | 1g | $385.99 |
| Choline tosylate | FCA35738 | 2g | $675.5 |
| Melting point | 95°C |
|---|---|
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | crystalline solid |
| color | White |
| Sensitive | Light Sensitive/Hygroscopic |
| InChI | InChI=1S/C7H8O3S.C5H14NO/c1-6-2-4-7(5-3-6)11(8,9)10;1-6(2,3)4-5-7/h2-5H,1H3,(H,8,9,10);7H,4-5H2,1-3H3/q;+1/p-1 |
| InChIKey | DVGVMQVOCJNXNJ-UHFFFAOYSA-M |
| SMILES | C1(S([O-])(=O)=O)C=CC(C)=CC=1.C(CO)[N+](C)(C)C |
| CAS DataBase Reference | 55357-38-5(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Irritant/Hygroscopic/Light Sensitive | |||||||||
| HS Code | 2923900090 | |||||||||
| NFPA 704 |
|
Choline tosylate price More Price(44)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | TRC-C433050-5G | Choline p-Toluenesulfonate Salt | 55357-38-5 | 5g | $354 | 2026-06-03 | Buy |
| TRC | TRC-C433050-10G | Choline p-Toluenesulfonate Salt | 55357-38-5 | 10g | $523 | 2026-06-03 | Buy |
| Biosynth | FCA35738 | Choline tosylate | 55357-38-5 | 0.5g | $241.25 | 2026-06-04 | Buy |
| Biosynth | FCA35738 | Choline tosylate | 55357-38-5 | 1g | $385.99 | 2026-06-04 | Buy |
| Biosynth | FCA35738 | Choline tosylate | 55357-38-5 | 2g | $675.5 | 2026-06-04 | Buy |
Choline tosylate Chemical Properties,Uses,Production
Uses
Choline p-Toluenesulfonate Salt is a useful intermediate as well as a choline acetyltransferase (CHAT) substrate.
Synthesis

A 500 mL reactor was charged at 25 C with 50 g (268.5 mmol) methyl tosylate and 100 mL acetone to which a solution of 25.1 g (281.6 mmol) N,N-dimethyl ethanolamine in 50.3 g acetone was added continuously at 25 C over 3 h. The dropping funnel was rinsed with additional acetone. The reaction mixture was stirred at 25 C for 20 h and the reaction progress was monitored by HPLC. When the level of methyltosylate was lower than 500 ppm the resulting suspension was cooled to 0 C over 150 min and the suspension was stirred at 0 C for 60 min. The product was collected by fdtration, washed two times with 175 mL acetone and dried under vacuum at 25 C to obtain 73.1 g (99 %) of choline tosylate as a white crystalline solid.
References
[1] Russian Chemical Bulletin, 1998, vol. 47, # 8, p. 1547 - 1549
[2] Tetrahedron Letters, 2009, vol. 50, # 28, p. 4092 - 4095
[3] Patent: JP5751578, 2015, B2. Location in patent: Paragraph 0017
[4] European Journal of Medicinal Chemistry, 2009, vol. 44, # 12, p. 4970 - 4977
[5] Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1988, vol. 37, p. 2293 - 2296
Choline tosylate Preparation Products And Raw materials
Choline tosylate Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Changzhou Ditong Chemical Co.,Ltd | +86-0519-88298848 | info@edengenechem.com | China | 2163 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49906 | 58 | |
| Jinan Liheng Biotechnology Co., Ltd. | 15865262812 | info@lihengpharm.com | CHINA | 937 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +86-13203830695 | laboratory@coreychem.com | China | 30203 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +86-189 4982 3763 | sales@tnjchem.com | China | 34526 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8618071025641 | eric@witopchemical.com | China | 23506 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 17705817739 | info@dycnchem.com | China | 52693 | 58 |
| PT CHEM GROUP LIMITED | +86-85511178; +86-85511178 | peter68@ptchemgroup.com | China | 35405 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +86-571-86217390; +8618058761490 | info@gihichemicals.com | China | 49860 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 +86-15355479329 | market18@leapchem.com | China | 43303 | 58 |
View Lastest Price from Choline tosylate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2021-08-12 | Choline tosylate
55357-38-5
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd |
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- Choline tosylate
55357-38-5
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
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