MPEG5-NHS
- CAS No.
- 1449390-12-8
- Chemical Name:
- MPEG5-NHS
- Synonyms
- mPEG6-NHS;m-PEG6-NHS ester;MPEG5-NHS;mPEG5-SPA;Methyl-PEG5-NHS ester;mPEG5-CH2CH2COONHS Ester;4,7,10,13,16,19-Hexaoxaeicosanoic acid, 2,5-dioxo-1-pyrrolidinyl ester;mPEG5-CH2CH2COONHS/4,7,10,13,16,19-Hexaoxaeicosanoic acid, 2,5-dioxo-1-pyrrolidinyl ester
- CBNumber:
- CB12546945
- Molecular Formula:
- C18H31NO10
- Molecular Weight:
- 421.44
- MDL Number:
- MFCD27977519
- MOL File:
- 1449390-12-8.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501 |
MPEG5-NHS price More Price(41)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | FM72944 | mPEG5-NHS | 1449390-12-8 | 250mg | $250 | 2026-06-04 | Buy |
| Biosynth | FM72944 | mPEG5-NHS | 1449390-12-8 | 100mg | $250 | 2026-06-04 | Buy |
| Biosynth | FM72944 | mPEG5-NHS | 1449390-12-8 | 500mg | $330 | 2026-06-04 | Buy |
| Biosynth | FM72944 | mPEG5-NHS | 1449390-12-8 | 1000mg | $580 | 2026-06-04 | Buy |
| Biosynth | FM72944 | mPEG5-NHS | 1449390-12-8 | 2000mg | $960 | 2026-06-04 | Buy |
MPEG5-NHS Chemical Properties, Uses, Production
Description
m-PEG6-NHS ester is a PEG linker containing an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The hydrophilic PEG spacer increases solubility in aqueous media.
Biological Activity
MPEG5-NHS is a non-cleavable 6-unit PEG-containing ADC linker for the synthesis of antibody drug conjugates (ADCs). It is a PROTAC linker belonging to the PEG/Alkyl/ether class, which can be used to synthesize PROTAC molecules.
in vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
target
| PEGs
| Alkyl/ether
| Non-cleavable
|
MPEG5-NHS Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 19011298796 19011298796 | 17816380947@139.com | China | 474 | 58 | |
| ChemPep, Inc. | +1 (888) 615-9178 / (561) 791-8787 | service@chempep.com | United States | 2138 | 57 |
| T&W GROUP | 021-61551611 13296011611 | contact@trustwe.com | China | 9884 | 58 |
| Nanjing Norris-Pharm Technology Co., Ltd | 13901585132 | sales@norris-pharm.com | China | 8869 | 55 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Hunan HuaTeng Pharmaceutical Co., Ltd., | 400-8592883 15367835770 | sales@huatengsci.com | China | 5869 | 58 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66028182 17714375163 | yftan@aikonchem.com | China | 16674 | 50 |
| Tongling HengYou Biotechnology Co., Ltd. | 021-50426030 13856289449;13124863828 | 2630597085@qq.com | China | 1885 | 55 |
| Borenpharm Co., Ltd | 027-65563561 | sales@borenpharm.com | China | 1245 | 55 |
| Jinan elephant international trading co., LTD | 13006575422@163.com | China | 6347 | 58 |
View Latest Price from MPEG5-NHS manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-08-03 | MPEG5-NHS
1449390-12-8
|
1KG | 98% | 1000kgs | Shaanxi Dideu New Materials Co. Ltd | ||
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2026-01-29 | mPEG5-CH2CH2COONHS ester
1449390-12-8
|
1g | 98% | 300kg | LAURENT | ||
![]() |
2025-06-07 | m-PEG6-NHS ester
1449390-12-8
|
1g | >98.00% | 1g | Xian confluore Biological Technology Co., Ltd. |
-

- MPEG5-NHS
1449390-12-8
- $0.00
- 98%
- Shaanxi Dideu New Materials Co. Ltd
-

- mPEG5-CH2CH2COONHS ester
1449390-12-8
- 98%
- LAURENT
-

- m-PEG6-NHS ester
1449390-12-8
- $0.00
- >98.00%
- Xian confluore Biological Technology Co., Ltd.





