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MPEG5-NHS

CAS No.
1449390-12-8
Chemical Name:
MPEG5-NHS
Synonyms
mPEG6-NHS;m-PEG6-NHS ester;MPEG5-NHS;mPEG5-SPA;Methyl-PEG5-NHS ester;mPEG5-CH2CH2COONHS Ester;4,7,10,13,16,19-Hexaoxaeicosanoic acid, 2,5-dioxo-1-pyrrolidinyl ester;mPEG5-CH2CH2COONHS/4,7,10,13,16,19-Hexaoxaeicosanoic acid, 2,5-dioxo-1-pyrrolidinyl ester
CBNumber:
CB12546945
Molecular Formula:
C18H31NO10
Molecular Weight:
421.44
MDL Number:
MFCD27977519
MOL File:
1449390-12-8.mol
MSDS File:
SDS
Last updated:2026-08-04 11:17:55

MPEG5-NHS Properties

Boiling point 502.6±60.0 °C(Predicted)
Density 1.21±0.1 g/cm3(Predicted)
storage temp. Storage temp. 2-8°C
solubility Soluble in DMSO, DCM, DMF
form Liquid
color Colorless to light yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

MPEG5-NHS price More Price(41)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth FM72944 mPEG5-NHS 1449390-12-8 250mg $250 2026-06-04 Buy
Biosynth FM72944 mPEG5-NHS 1449390-12-8 100mg $250 2026-06-04 Buy
Biosynth FM72944 mPEG5-NHS 1449390-12-8 500mg $330 2026-06-04 Buy
Biosynth FM72944 mPEG5-NHS 1449390-12-8 1000mg $580 2026-06-04 Buy
Biosynth FM72944 mPEG5-NHS 1449390-12-8 2000mg $960 2026-06-04 Buy
Product number Packaging Price Buy
FM72944 250mg $250 Buy
FM72944 100mg $250 Buy
FM72944 500mg $330 Buy
FM72944 1000mg $580 Buy
FM72944 2000mg $960 Buy

MPEG5-NHS Chemical Properties, Uses, Production

Description

m-PEG6-NHS ester is a PEG linker containing an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The hydrophilic PEG spacer increases solubility in aqueous media.

Biological Activity

MPEG5-NHS is a non-cleavable 6-unit PEG-containing ADC linker for the synthesis of antibody drug conjugates (ADCs). It is a PROTAC linker belonging to the PEG/Alkyl/ether class, which can be used to synthesize PROTAC molecules.

in vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

target

PEGs

Alkyl/ether

Non-cleavable

MPEG5-NHS Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 68)
Supplier Tel Email Country ProdList Advantage
19011298796 19011298796 17816380947@139.com China 474 58
ChemPep, Inc. +1 (888) 615-9178 / (561) 791-8787 service@chempep.com United States 2138 57
T&W GROUP 021-61551611 13296011611 contact@trustwe.com China 9884 58
Nanjing Norris-Pharm Technology Co., Ltd 13901585132 sales@norris-pharm.com China 8869 55
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Hunan HuaTeng Pharmaceutical Co., Ltd., 400-8592883 15367835770 sales@huatengsci.com China 5869 58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66028182 17714375163 yftan@aikonchem.com China 16674 50
Tongling HengYou Biotechnology Co., Ltd. 021-50426030 13856289449;13124863828 2630597085@qq.com China 1885 55
Borenpharm Co., Ltd 027-65563561 sales@borenpharm.com China 1245 55
Jinan elephant international trading co., LTD 13006575422@163.com China 6347 58

View Latest Price from MPEG5-NHS manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
MPEG5-NHS pictures 2026-08-03 MPEG5-NHS
1449390-12-8
1KG 98% 1000kgs Shaanxi Dideu New Materials Co. Ltd
mPEG5-CH2CH2COONHS ester pictures 2026-01-29 mPEG5-CH2CH2COONHS ester
1449390-12-8
1g 98% 300kg LAURENT
m-PEG6-NHS ester pictures 2025-06-07 m-PEG6-NHS ester
1449390-12-8
1g >98.00% 1g Xian confluore Biological Technology Co., Ltd.
  • MPEG5-NHS pictures
  • MPEG5-NHS
    1449390-12-8
  • $0.00
  • 98%
  • Shaanxi Dideu New Materials Co. Ltd
  • m-PEG6-NHS ester pictures
  • m-PEG6-NHS ester
    1449390-12-8
  • $0.00
  • >98.00%
  • Xian confluore Biological Technology Co., Ltd.

MPEG5-NHS Spectrum

MPEG5-NHS 4,7,10,13,16,19-Hexaoxaeicosanoic acid, 2,5-dioxo-1-pyrrolidinyl ester mPEG5-CH2CH2COONHS Ester Methyl-PEG5-NHS ester mPEG5-SPA mPEG5-CH2CH2COONHS/4,7,10,13,16,19-Hexaoxaeicosanoic acid, 2,5-dioxo-1-pyrrolidinyl ester m-PEG6-NHS ester mPEG6-NHS 1449390-12-8 C18H31NO10 mPEG