5-Chloro-3-nitropyridine-2-carboxaldehyde
- CAS No.
- 1086838-13-2
- Chemical Name:
- 5-Chloro-3-nitropyridine-2-carboxaldehyde
- Synonyms
- 5-Chloro-3-nitropicolinaldehyde;5-chloro-3-nitropyridine-2-carbaldehyde;5-Chloro-3-nitropyridine-2-carboxaldehyde;2-Pyridinecarboxaldehyde, 5-chloro-3-nitro-
- CBNumber:
- CB12629929
- Molecular Formula:
- C6H3ClN2O3
- Molecular Weight:
- 186.55
- MDL Number:
- MFCD18250468
- MOL File:
- 1086838-13-2.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 5-Chloro-3-nitropicolinaldehyde | 301044 | 50.00mg | $134 |
| 5-Chloro-3-nitropicolinaldehyde | 301044 | 100.00mg | $197 |
| 5-Chloro-3-nitropicolinaldehyde | 301044 | 250.00mg | $260 |
| 5-Chloro-3-nitropicolinaldehyde 95+% | C41842 | 50mg | $271 |
| 5-Chloro-3-nitropicolinaldehyde 95+% | C41842 | 100mg | $420 |
| More product size | |||
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P280-P305+P351+P338 |
5-Chloro-3-nitropyridine-2-carboxaldehyde price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Matrix Scientific | 301044 | 5-Chloro-3-nitropicolinaldehyde | 1086838-13-2 | 50.00mg | $134 | 2026-05-19 | Buy |
| Matrix Scientific | 301044 | 5-Chloro-3-nitropicolinaldehyde | 1086838-13-2 | 100.00mg | $197 | 2026-05-19 | Buy |
| Matrix Scientific | 301044 | 5-Chloro-3-nitropicolinaldehyde | 1086838-13-2 | 250.00mg | $260 | 2026-05-19 | Buy |
| Synthonix | C41842 | 5-Chloro-3-nitropicolinaldehyde 95+% | 1086838-13-2 | 50mg | $271 | 2026-05-06 | Buy |
| Synthonix | C41842 | 5-Chloro-3-nitropicolinaldehyde 95+% | 1086838-13-2 | 100mg | $420 | 2026-05-06 | Buy |
5-Chloro-3-nitropyridine-2-carboxaldehyde Chemical Properties,Uses,Production
Synthesis
1086838-15-4
1086838-13-2
The general procedure for the synthesis of 5-chloro-3-nitropyridine-2-carbaldehyde from the compound (CAS:1086838-15-4) is as follows: first, 2-amino-3-(6-chloro-3-methoxy-2H-pyrazolo[4,3-b]pyridin-2-yl)-2-methylpropanenitrile (39 mg) was prepared in quantitative amounts according to a method similar to that described in the preceding. Referring to the operation of Example 1 part b, but using 1-(6-chloro-3-methoxy-2H-pyrazolo[4,3-b]pyridin-2-yl)propan-2-one (32 mg) as a starting material. 1-(6-chloro-3-methoxy-2H-pyrazolo[4,3-b]pyridin-2-yl)propan-2-one was prepared similarly as described in Example 105. Next, the method of Example 136 parts a to d was followed, but using 5-chloro-3-nitropyridine-2-carboxaldehyde (1.2 g) and decaborane from part a to prepare [2-(tert-butyldimethylsilyloxy)propyl]-(5-chloro-3-nitropyridin-2-yl)methanamine (0.4 g in 17% yield). 5-chloro-3-nitropyridine-2-carboxaldehyde was prepared similarly to that described in Example 136 parts a to c, with the difference that one starts with 2-amino-5-chloro-3-nitropyridine in part a or uses commercially available 2-bromo-5-chloro-3-nitropyridine as a starting material for part b. The method of preparing 5-chloro-3-nitropyridine-2-carbaldehyde is similar to that described in Example 136 parts a to c. Additionally, the ozonolysis step of part c can be replaced by oxidative cracking using a 4% aqueous osmium tetroxide solution (2 mL) and sodium periodate (1.2 g) in a mixture of THF and water (10:1, 20 mL). Finally, 5-chloro-3-nitro-2-vinylpyridine (1 g) was prepared from 5-chloro-3-nitropyridine-2-carbaldehyde (0.72 g, 72% yield) with reference to the method of Example 61.
References
[1] Patent: WO2008/144275, 2008, A1. Location in patent: Page/Page column 105
5-Chloro-3-nitropyridine-2-carboxaldehyde Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29626 | 60 |
| Chiba Pharmaceutical Science and technology Co, Ltd. | 0531-81313138 13066006660 | chibapharm@foxmail.com | China | 3998 | 55 |
| Shijiazhuang Jing Kang Technology Co.Ltd. | 13933818572 | 1519554262@qq.com | China | 1785 | 58 |
| Aikon International Limited | 025-58859352 13913916777 | dt3@aikonchem.com | China | 15490 | 58 |
| Suzhou Nuoouman Biological Technology Co., Ltd. | 15026866316 | 180642609@qq.com | China | 4969 | 58 |
| Shanghai Benso Pharmaceutical Technology Co., Ltd. | 15088289376;13917786310 | 248775804@qq.com | China | 4916 | 58 |
| Suzhou bayaoke Biotechnology Co., Ltd | 18626188356 | 1058187422@qq.com | China | 510 | 58 |
| Huansheng Meisen Pharmaceutical Technology (Shandong) Co., Ltd | 0531-88762217 18301471076 | sales@acespharma.com | China | 3859 | 58 |
| Shanghai Haohong Pharmaceutical Co., Ltd. | 400-8210725 4008210725 | malulu@leyan.com | China | 54996 | 58 |
| Energy Chemical | 400-0056266 | marketing1@energy-chemical.com | China | 44926 | 58 |
