AGN 196996
- CAS No.
- 958295-17-5
- Chemical Name:
- AGN 196996
- Synonyms
- CS-1210;AGN 196996;VTP 196696;AGN 196996, 10 mM in DMSO;4-(3-Bromo-4-ethoxy-5-(4-methylbenzoyl)benzamido)benzoic acid;4-[[3-Bromo-4-ethoxy-5-(4-methylbenzoyl)benzoyl]amino]benzoic acid;Benzoic acid, 4-[[3-bromo-4-ethoxy-5-(4-methylbenzoyl)benzoyl]amino]-
- CBNumber:
- CB12715604
- Molecular Formula:
- C24H20BrNO5
- Molecular Weight:
- 482.32
- MDL Number:
- MFCD28167794
- MOL File:
- 958295-17-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
AGN 196996 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | INB29517 | 4-[[3-Bromo-4-ethoxy-5-(4-methylbenzoyl)benzoyl]amino]benzoic acid | 958295-17-5 | 25mg | $1231.75 | 2026-06-04 | Buy |
| Biosynth | INB29517 | 4-[[3-Bromo-4-ethoxy-5-(4-methylbenzoyl)benzoyl]amino]benzoic acid | 958295-17-5 | 50mg | $1713.5 | 2026-06-04 | Buy |
| Biosynth | INB29517 | 4-[[3-Bromo-4-ethoxy-5-(4-methylbenzoyl)benzoyl]amino]benzoic acid | 958295-17-5 | 100mg | $2741 | 2026-06-04 | Buy |
| ChemScene | CS-3201 | AGN 196996 99.76% | 958295-17-5 | 5mg | $292 | 2026-06-04 | Buy |
| ChemScene | CS-3201 | AGN 196996 99.76% | 958295-17-5 | 10mg | $439 | 2026-06-04 | Buy |
AGN 196996 Chemical Properties, Uses, Production
Description
AGN 196996 is a potent and selective RARα antagonist with Ki value of 2 nM; little binding affinity for RARβ(Ki=1087 nM) and RARγ(Ki=8523 nM). IC50 value: 2 nM(Ki) Target: RARα antagonist AGN 196996 shows no activity in transactivation assays, but instead block the gene transcriptional activity induced by ATRA and other RAR agonists.
Uses
AGN 196996 is a potent and selective RARα antagonist with Ki value of 2 nM; little binding affinity for RARβ(Ki=1087 nM) and RARγ(Ki=8523 nM). IC50 value: 2 nM(Ki) Target: RARα antagonist AGN 196996 shows no activity in transactivation assays, but instead block the gene transcriptional activity induced by ATRA and other RAR agonists.
References
References:[1]. Hammond LA, et al. Antagonists of retinoic acid receptors (RARs) are potent growth inhibitors of prostate carcinoma cells. Br J Cancer. 2001 Aug 3;85(3):453-62. [2]. Keedwell RG, et al. An antagonist of retinoic acid receptors more effectively inhibits growth of human prostate cancer cells than normal prostate epithelium. Br J Cancer. 2004 Aug 2;91(3):580-8.
AGN 196996 Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd. | 17702719238 | sales@sun-shinechem.com | China | 1197 | 64 |
| MedChemexpress LLC | 021-58955995 | sales@medchemexpress.cn | United States | 4853 | 58 |
| SPIRO PHARMA | eric_feng1954@126.com | China | 9239 | 55 | |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| ShangHai Biochempartner Co.,Ltd | 177-54423994 17754423994 | 2853530910@QQ.com | China | 8000 | 62 |
| Musechem | +1-800-259-7612 | info@musechem.com | United States | 4648 | 60 |
| Angel Pharmatech, Ltd. | 17317130613 | 3358272972@qq.com | China | 3307 | 58 |
| Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 | liming@bio-fount.com | China | 9718 | 58 |
| BOC Sciences | 16314854226; +8616314854226 | inquiry@bocsci.com | United States | 19852 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
View Latest Price from AGN 196996 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-08 | AGN 196996
958295-17-5
|
$32.00-120.00 | 99.94% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-08-08 | AGN 196996
958295-17-5
|
$32.00-120.00 | 99.94% | 10g | TargetMol Chemicals Inc. | ||
 |
2025-05-12 | AGN 196996
958295-17-5
|
$54.00-200.00 | 10g | TargetMol Chemicals Inc. |
-
- AGN 196996
958295-17-5
- $32.00-120.00
- 99.94%
- TargetMol Chemicals Inc.
-
- AGN 196996
958295-17-5
- $32.00-120.00
- 99.94%
- TargetMol Chemicals Inc.
-
- AGN 196996
958295-17-5
- $54.00-200.00
- TargetMol Chemicals Inc.
