(S)-2-Amino-3-(5-fluoro-1H-indol-3-yl)-propionic acid
- CAS No.
- 16626-02-1
- Chemical Name:
- (S)-2-Amino-3-(5-fluoro-1H-indol-3-yl)-propionic acid
- Synonyms
- 5-FLUORO-L-TRYPTOPHAN;L-5-FLUOROTRYPTOPHAN;(S)-2-AMino-3-(5-fluoro-1H-indol-3-yl)propanoic acid;L-Trp(5-F)-OH;UNII:5IC9663SHW;H-L-Trp(5-F)-OH*H2O;H-5-FLUORO-TRP-OH H2O;Tryptophan Impurity 54;5-fluoro-L-tryptophans;L-Tryptophan, 5-fluoro-
- CBNumber:
- CB1274150
- Molecular Formula:
- C11H11FN2O2
- Molecular Weight:
- 222.22
- MDL Number:
- MFCD00066470
- MOL File:
- 16626-02-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 238-239 °C |
|---|---|
| Boiling point | 450.7±45.0 °C(Predicted) |
| Density | 1.442±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| pka | 2.21±0.10(Predicted) |
| form | powder |
| color | white |
| BRN | 5052680 |
| InChI | InChI=1S/C11H11FN2O2/c12-7-1-2-10-8(4-7)6(5-14-10)3-9(13)11(15)16/h1-2,4-5,9,14H,3,13H2,(H,15,16)/t9-/m0/s1 |
| InChIKey | INPQIVHQSQUEAJ-VIFPVBQESA-N |
| SMILES | C(O)(=O)[C@H](CC1C2=C(C=CC(F)=C2)NC=1)N |
| FDA UNII | 17H03VO4KZ |
| UNSPSC Code | 12352209 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| PPE | Eyeshields, Gloves, type N95 (US) |
| Safety Statements | 22-24/25 |
| WGK Germany | 3 |
| F | 10 |
| HS Code | 2933998090 |
| Storage Class | 11 - Combustible Solids |
(S)-2-Amino-3-(5-fluoro-1H-indol-3-yl)-propionic acid price More Price(43)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SMB01347 | 5-Fluoro- |
16626-02-1 | 25mg | $157 | 2026-04-30 | Buy |
| Sigma-Aldrich | 47568 | 5-Fluoro-L-tryptophan ≥98.0% (HPLC) | 16626-02-1 | 25mg | $205 | 2026-04-30 | Buy |
| Sigma-Aldrich | SMB01347 | 5-Fluoro- |
16626-02-1 | 50mg | $227.5 | 2025-07-31 | Buy |
| Biosynth | FF77439 | 5-Fluoro-L-tryptophan | 16626-02-1 | 0.5g | $534.06 | 2026-06-04 | Buy |
| Biosynth | FF77439 | 5-Fluoro-L-tryptophan | 16626-02-1 | 1g | $928.76 | 2026-06-04 | Buy |
(S)-2-Amino-3-(5-fluoro-1H-indol-3-yl)-propionic acid Chemical Properties, Uses, Production
Uses
Exogenous 5-fluoro-Trp is incorporated into proteins in normal protein synthesis. Since 19F is a useful reporter group, this provides a method for studying enzyme mechanisms by NMR.
Biochem/physiol Actions
5-Fluoro-Trp is nonspecifically cytotoxic. It is believed this is due to malfunctioning enzymes that have had replacements of Trp residues by 5-fluoro-Trp. However, at least one case is known where 5-fluoro-Trp substitution leads to significantly greater catalytic activity.
Purification Methods
Recrystallise it from EtOH, aqueous EtOH or AcOH. Also purify it by passage through a Dowex AG1x2 (acetate form) column and recrystallise the L-enantiomer (from enzymic enrichment) from H2O/EtOH, m 158-163o(dec), [] D -8.3o (c 2.5, N NaOH). [Coy et al. Biochemistry 13 3550 1974, Beilstein 22/14 V 116.]
(S)-2-Amino-3-(5-fluoro-1H-indol-3-yl)-propionic acid Preparation Products And Raw materials
Raw materials
Preparation Products
(S)-2-Amino-3-(5-fluoro-1H-indol-3-yl)-propionic acid Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shandong Shining Pharm Co.,Ltd | 18866891188 18866891188 | zhaojiangxia@shiningpharm.com | China | 203 | 58 |
| Hangzhou Huiyi Biotechnology Co., LTD | 0571-89918262 13357170655 | chenlingwei@hizyme.com | China | 103 | 58 |
| Shandong Xuanshuo Pharmaceutical Technology Co. LTD | 15269103900 | suchangzhou@shiningpharm.com | China | 384 | 58 |
| SICHUAN TONGSHENG BIOPHARMACEUTICAL CO., LTD | 0838-2809458 13350585791 | pharm@biots.cn | China | 778 | 58 |
| Suzhou Biosyntech Co., Ltd. | +86-0512-63001269 15720870325 | sales2@biosyntech-suzhou.com | China | 182 | 58 |
| Ningbo Enzyme Chemical Co., LTD | 0574-+86-574-8773-0716-654-654 18042089573 | yufang.jiang@enzymaster.com | China | 42 | 58 |
| WuYan Pharmaceutical Technology (Shanghai) Co., Ltd. | 18621565901 | sales@wuyanpharm.com | China | 139 | 55 |
| Syncozymes (Shanghai) Co.,Ltd. | 021-68187180 13681683526 | lchen@syncozymes.com | China | 412 | 55 |
| Nordijia Biopharmaceutical (Suzhou) Co., Ltd. | 15150674956 | dannielee@nordicabio.com | China | 339 | 58 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
View Latest Price from (S)-2-Amino-3-(5-fluoro-1H-indol-3-yl)-propionic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-09-17 | 5-FLUORO-L-tryptophan
16626-02-1
|
$1.00 | 1g/Bag | 98.7 | 100 KG | Hangzhou Zhenhe Huacheng BioPharm Tech Co., Ltd. |
-

- 5-FLUORO-L-tryptophan
16626-02-1
- $1.00
- 98.7
- Hangzhou Zhenhe Huacheng BioPharm Tech Co., Ltd.
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