11-Deoxy-16,16-dimethyl prostaglandin E2
- CAS No.
- 53658-98-3
- Chemical Name:
- 11-Deoxy-16,16-dimethyl prostaglandin E2
- Synonyms
- AY 24609;11-Deoxy-16,16-dimethyl prostaglandin E2;9-OXO-15R-HYDROXY-16,16-DIMETHYL-PROSTA-5Z,13E-DIEN-1-OIC ACID;Prosta-5,13-dien-1-oic acid, 15-hydroxy-16,16-dimethyl-9-oxo-, (5Z,13E,15R)-
- CBNumber:
- CB1274529
- Molecular Formula:
- C22H36O4
- Molecular Weight:
- 364.52
- MDL Number:
- MFCD00135216
- MOL File:
- 53658-98-3.mol
- MSDS File:
- SDS
| Boiling point | 522.593±45.00 °C(Press: 760.00 Torr)(predicted) |
|---|---|
| Density | 1.063±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) |
| solubility | DMF: >100 mg/ml (from PGE2); DMSO: >100 mg/ml (from PGE2); Ethanol: >100 mg/ml (from PGE2); PBS pH 7.2: >5 mg/ml (from PGE2) |
| pka | 4.754±0.10(predicted) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS02,GHS07,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H225-H319-H360-H336 | |||||||||
| Precautionary statements | P201-P202-P210-P240-P241-P242-P243-P261-P264-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P308+P313-P312-P337+P313-P370+P378-P403+P233-P403+P235-P405-P501 | |||||||||
| NFPA 704 |
|
11-Deoxy-16,16-dimethyl prostaglandin E2 price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 14570 | 11-deoxy-16,16-dimethyl Prostaglandin E2 ≥98% | 53658-98-3 | 1mg | $71 | 2026-04-30 | Buy |
| Cayman Chemical | 14570 | 11-deoxy-16,16-dimethyl Prostaglandin E2 ≥98% | 53658-98-3 | 5mg | $308 | 2026-04-30 | Buy |
| Cayman Chemical | 14570 | 11-deoxy-16,16-dimethyl Prostaglandin E2 ≥98% | 53658-98-3 | 10mg | $547 | 2026-04-30 | Buy |
| TRC | A795100 | AY24609 | 53658-98-3 | 2.5mg | $560 | 2021-12-16 | Buy |
11-Deoxy-16,16-dimethyl prostaglandin E2 Chemical Properties, Uses, Production
Description
11-
Uses
AY 24609 is an analogue of PGE2 and a selective EP2 and EP3 receptors agonist. It also inhibits gastric acid secretion and ulcer formation in rat.
Definition
ChEBI: 11-Deoxy-16,16-dimethyl-PGE2 is a prostanoid.
IC 50
EP2; EP3
References
[1] R.F. PARROTT S. V V. Effects of centrally administered prostaglandin EP receptor agonists on febrile and adrenocortical responses in the prepubertal pig[J]. Brain Research Bulletin, 1996, 41 2: Pages 97-103. DOI: 10.1016/0361-9230(96)00156-6
[2] LIPPMANN W. Inhibition of gastric acid secretion and ulcer formation in the rat by orally-administered 11-deoxyprostaglandin analogues: 15-hydroxy-16,16-dimethyl-9-oxoprost-5,13-dienoic acids[J]. Prostaglandins, 1974, 7 3: Pages 231-246. DOI: 10.1016/0090-6980(74)90007-0
11-Deoxy-16,16-dimethyl prostaglandin E2 Preparation Products And Raw materials
Raw materials
Preparation Products
11-Deoxy-16,16-dimethyl prostaglandin E2 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | 16314854226 | info@bocsci.com | United States | 9909 | 65 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 400-920-5774 | sales@glpbio.cn | China | 6705 | 58 |
| BOC Sciences | 16314854226; +8616314854226 | inquiry@bocsci.com | United States | 19852 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11963 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| Supplier | Advantage |
|---|---|
| BOC Sciences | 65 |
| Shanghai Hongye Biotechnology Co. Ltd | 58 |
| BOC Sciences | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 58 |
| TargetMol Chemicals Inc. | 58 |
