cAMP-dependent protein kinase type I-alpha regulatory subunit
- CAS No.
- Chemical Name:
- cAMP-dependent protein kinase type I-alpha regulatory subunit
- Synonyms
- PKR1;TSE1;KAP0;GPR73;PRKAR1;GPR73a;PRKAR1A;PKA R1-α;PRKAR1B, His tagged human;G-protein coupled receptor 73
- CBNumber:
- CB12908529
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
cAMP-dependent protein kinase type I-alpha regulatory subunit price More Price(7)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SAB1306431 | ANTI-PROTEIN KINASE A REGULATORY SUBUNIT I ALPHA(N-TERMINAL) antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution | 400μL | $461 | 2023-01-07 | Buy | |
| Usbiological | 527048 | PKR1 Purifiedbyimmunoaffinitychromatography. | 100ul | $736 | 2026-06-03 | Buy | |
| Usbiological | 527048 | PKR1 Purifiedbyimmunoaffinitychromatography. | 200ul | $944 | 2026-06-03 | Buy | |
| Usbiological | 403666 | PKR1 Purifiedbyimmunoaffinitychromatography. | 50ul | $531 | 2026-06-03 | Buy | |
| Usbiological | 403666 | PKR1 Purifiedbyimmunoaffinitychromatography. | 100ul | $701 | 2026-06-03 | Buy |
cAMP-dependent protein kinase type I-alpha regulatory subunit Chemical Properties, Uses, Production
Description
cAMP-dependent PKA is an ubiquitous serine/theonine protein kinase present in a variety of tissues (e.g. brain, skeletal muscle, heart). The intracellular cAMP level regulates cellular responses by altering the interaction between the catatytic C and regulatory R subunits of PKA. The inactive tetrameric PKA holoenzyme R2C2 is activated when cAMP binds to R2, which dissociates the tetramer to R2 cAMP 4 and two active catalytic subunits. Free Catalytic subunits of PKA can phosphorylate a wide variety of intracellular target proteins. In response to hormone- induced high cAMP levels, PKA phosphorylates glycogen synthetase (inhibition of the enzyme activity) and phosphorylase kinase to block glycogen synthesis. Different isoforms of catalytic and regulatory subunits suggest specific functions. The recombinant PKA regulatory subunit I a is a dimeric 90kDa protein.
Source
Escherichia Coli
cAMP-dependent protein kinase type I-alpha regulatory subunit Preparation Products And Raw materials
Raw materials
Preparation Products
cAMP-dependent protein kinase type I-alpha regulatory subunit Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Wuhan Chemstan Biotechnology Co., Ltd. | 027-65317797 15926423062 | 422450190@qq.com | China | 10305 | 58 |
| Shanghai Yubo Biotechnology Co., Ltd | 021-60514606 18321282235 | sale1@shybsw.net | China | 8165 | 58 |
| shlmai | 021-67680335 13052188602 | sale1@shlmai.net | China | 10000 | 58 |
| Supplier | Advantage |
|---|---|
| Wuhan Chemstan Biotechnology Co., Ltd. | 58 |
| Shanghai Yubo Biotechnology Co., Ltd | 58 |
| shlmai | 58 |
