RSPO1
- CAS No.
- Chemical Name:
- RSPO1
- Synonyms
- R-spondin 1;RSPO;RSPO1;HRspo1;FLJ40906;CRISTIN3;RSPONDIN;R-SPONDIN-1 human;Roof plate-specific spondin-1;Recombinant Human RSPO1 Protein, His Tag
- CBNumber:
- CB12912843
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
RSPO1 price More Price(11)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SRP3292 | R-SPONDIN-1 human recombinant, expressed in CHO cells, ≥95% (SDS-PAGE), ≥95% (HPLC) | 20μG | $407 | 2026-04-30 | Buy | |
| Sigma-Aldrich | SRP6487 | R spondin-1 human recombinant, expressed in HEK 293 cells, ≥98% (SDS-PAGE) | 10μG | $330 | 2022-05-15 | Buy | |
| Usbiological | 527462 | R-spondin1 Purifiedbyaffinitychromatography. | 100ul | $758 | 2026-06-03 | Buy | |
| Usbiological | 527462 | R-spondin1 Purifiedbyaffinitychromatography. | 200ul | $984 | 2026-06-03 | Buy | |
| Usbiological | 156572 | R-Spondin 1 | 10ug | $350 | 2021-12-16 | Buy |
RSPO1 Chemical Properties, Uses, Production
Uses
R-Spondin-1 (Rspo-1) belongs to the (Rspo) family of Wnt modulators. Currently, the (Rspo) family consists of four structurally related secreted ligands (Rspo 1-4), all containing furin-like and thrombospondin structural domains. Rspo-1 is expressed in certain areas of the developing central nervous system, as well as in adrenal glands, ovary, testis, thyroid, and trachea. Recombinant human R-Spondin-1 is a 26.7kDa protein consisting of 243 amino acid residues. Due to glycosylation, R-Spondin-1 migrates at an apparent molecular weight of approximately 40.0kDa by SDS PAGE analysis under reducing conditions.
General Description
R-Spondin-1 (Rspo-1) belongs to the (Rspo) family of Wnt modulators. Currently, the (Rspo) family consists of four structurally related secreted ligands (Rspo 1-4), all containing furin-like and thrombospondin structural domains. Rspo-1 is expressed in certain areas of the developing central nervous system, as well as in adrenal glands, ovary, testis, thyroid, and trachea. Recombinant human R-Spondin-1 is a 26.7kDa protein consisting of 243 amino acid residues. Due to glycosylation, R-Spondin-1 migrates at an apparent molecular weight of approximately 40.0kDa by SDS PAGE analysis under reducing conditions.
Biochem/physiol Actions
Rspo (R-Spondin) can interact with the Frizzled/LRP6 (LDL receptor related protein 6) receptor complex in a manner that stimulates the Wnt/beta-catenin signaling pathway. Disruption of Rspo-1 gene causes recessive syndrome with XX sex reversal, palmoplantar hyperkeratosis and predisposition to squamous cell carcinoma of the skin. Rspo-1 is also associated with radioresistance of tumor cells.
RSPO1 Preparation Products And Raw materials
Raw materials
Preparation Products
RSPO1 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51389 | 80 |
| Wuhan Chemstan Biotechnology Co., Ltd. | 027-65317797 15926423062 | 422450190@qq.com | China | 10305 | 58 |
| Gongyishengan Technology (Shenzhen) Co., Ltd. | 0755-89218110 13480856786 | 2880189130@qq.com | China | 984 | 58 |
| Biolab Reagents | 027-65279366 18108604356 | products@biolabreagent.com | China | 9864 | 58 |
| ACROBiosystems | 13121935750 | jiaxin.zhao@acrobiosystems.com | China | 1592 | 58 |
| Shanghai Yubo Biotechnology Co., Ltd | 021-60514606 18321282235 | sale1@shybsw.net | China | 8165 | 58 |
| Supplier | Advantage |
|---|---|
| Sigma-Aldrich | 80 |
| Wuhan Chemstan Biotechnology Co., Ltd. | 58 |
| Gongyishengan Technology (Shenzhen) Co., Ltd. | 58 |
| Biolab Reagents | 58 |
| ACROBiosystems | 58 |
| Shanghai Yubo Biotechnology Co., Ltd | 58 |
