2-(4-Fluorophenyl)-thiophene
- CAS No.
- 58861-48-6
- Chemical Name:
- 2-(4-Fluorophenyl)-thiophene
- Synonyms
- 2-(4-FLUOROPHENYL)THIOPHENE;Canagliflozin intermediate;2-(4-FL;AKOS BAR-1344;Canagliflozin INT2;IFLAB-BB F2108-0130;Impurity of caglitazin;FLUOROPHENYL)THIOPHENE;Cagliflozin Impurity 14;2-(4-Fluorphenyl)thiophen
- CBNumber:
- CB1294813
- Molecular Formula:
- C10H7FS
- Molecular Weight:
- 178.23
- MDL Number:
- MFCD06802535
- MOL File:
- 58861-48-6.mol
- MSDS File:
- SDS
| Melting point | 51.0 to 55.0 °C |
|---|---|
| Boiling point | 252.3±15.0 °C(Predicted) |
| Density | 1.200±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C(protect from light) |
| solubility | soluble in Methanol |
| form | powder to crystal |
| color | Light orange to Yellow to Green |
| InChI | InChI=1S/C10H7FS/c11-9-5-3-8(4-6-9)10-2-1-7-12-10/h1-7H |
| InChIKey | PURJRGMZIKXDMW-UHFFFAOYSA-N |
| SMILES | C1(C2=CC=C(F)C=C2)SC=CC=1 |
| CAS DataBase Reference | 58861-48-6 |
| FDA UNII | 72TG563TMB |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302+H312+H332-H315-H319 |
| Precautionary statements | P501-P261-P270-P271-P264-P280-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330-P302+P352+P312-P304+P340+P312 |
| HS Code | 2934999090 |
| REACH Registrations | Active |
2-(4-Fluorophenyl)-thiophene price More Price(62)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | F0724 | 2-(4-Fluorophenyl)thiophene >95.0%(GC) | 58861-48-6 | 1g | $36 | 2026-04-30 | Buy |
| TCI Chemical | F0724 | 2-(4-Fluorophenyl)thiophene >95.0%(GC) | 58861-48-6 | 5g | $110 | 2026-04-30 | Buy |
| Biosynth | FF62249 | 2-(4-Fluorophenyl)thiophene | 58861-48-6 | 50g | $900 | 2026-06-04 | Buy |
| Biosynth | FF62249 | 2-(4-Fluorophenyl)thiophene | 58861-48-6 | 25g | $900 | 2026-06-04 | Buy |
| Biosynth | FF62249 | 2-(4-Fluorophenyl)thiophene | 58861-48-6 | 250g | $900 | 2026-06-04 | Buy |
2-(4-Fluorophenyl)-thiophene Chemical Properties,Uses,Production
Chemical Properties
white solid
Uses
2-(4-Fluorophenyl)-thiophene can be used to prepare Canagliflozin (C175190) as sodium-dependent glucose co-transporter 2 (SGLT2) inhibitor for treatment of type 2 diabetes mellitus.
Synthesis
4-fluorobenzoic boric acid and 2-bromothiophene, Pd catalyst are added in organic solvent and dissolves, obtain material 3, wherein: 4-fluorine Phenylboric acid molar concentration in organic solvent is 0.5mol/L～2mol/L, and 4-fluorobenzoic boric acid with the mol ratio of 2-bromothiophene is 1:1.0～1:1.5,4-fluorobenzoic boric acid is 1:0.005～1:0.1 with the mol ratio of catalyst；Using material 3 with as material 4 Inorganic base aqueous solution carries out pre-incubation respectively to being 1:1.0～1 according to the mol ratio of 4-fluorobenzoic boric acid Yu alkali after reaction temperature: The mode of 3.0 mixes, and reacts under conditions of 50 ℃～80 ℃, then carries out post processing and obtains 2-(4-fluorophenyl) Thiophene.
2-(4-Fluorophenyl)-thiophene Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Cangzhou Senary Chemical Science-tech Co., Ltd. | 0317-5482966 17732392080;17736968590;17732392081 | trade@senary.com | China | 56 | 58 |
| Inner Mongolia Slanke Pharm-Tech Co., Ltd | 0479-2224266; 15047962002;15734819719 | 1304140798@qq.com | China | 73 | 58 |
| Hebei Maison Chemical Co.,Ltd. | 155-11852758; 18408670720 | ruby@maisonchem.com.cn | China | 687 | 58 |
| Anqing CHICO Pharmaceutical Co., Ltd. | 18061456370 | sales@chicopharm.com | China | 500 | 65 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
View Lastest Price from 2-(4-Fluorophenyl)-thiophene manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-02 | 2-(4-Fluorophenyl)-thiophene
58861-48-6
|
$5.00 | 1KG | 99% | Henan Fengda Chemical Co., Ltd | ||
 |
2026-08-20 | 2-(4-FLUOROPHENYL)THIOPHENE
58861-48-6
|
$1.10 | 1g | 99.00% | 100 Tons | Dideu Industries Group Limited | |
 |
2026-06-30 | 2-(4-Fluorophenyl)-thiophene
58861-48-6
|
1kg | 98% | 1000kgs | Shaanxi Dideu New Materials Co. Ltd |
-
- 2-(4-Fluorophenyl)-thiophene
58861-48-6
- $5.00
- 99%
- Henan Fengda Chemical Co., Ltd
-
- 2-(4-FLUOROPHENYL)THIOPHENE
58861-48-6
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 2-(4-Fluorophenyl)-thiophene
58861-48-6
- $0.00
- 98%
- Shaanxi Dideu New Materials Co. Ltd
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