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(S)-(-)-METOPROLOL

(S)-(-)-METOPROLOL Structure
(S)-(-)-METOPROLOL structure
CAS No.
81024-42-2
Chemical Name:
(S)-(-)-METOPROLOL
Synonyms
(S)-(-)-METOPROLOL;Metoprolol S-Isomer;Metoprolol Impurity 28;Metoprolol EP Impurity 18;(S)-(-)-METOPROLOL USP/EP/BP;Metoprolol Impurity 5(S)-Metoprolol;(S)-1-(isopropylamino)-3-(4-(2-methoxyethyl)phenoxy)propan-2-ol;(2S)-1-[4-(2-methoxyethyl)phenoxy]-3-(propan-2-ylamino)propan-2-ol;(2S)-1-[4-(2-Methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]-2-propanol;[(2S)-1-[4-(2-Methoxyethyl)phenoxy]-3-[(1-methylethyl)-amino]propan-2-ol
CBNumber:
CB1297359
Molecular Formula:
C15H25NO3
Molecular Weight:
267.36
MDL Number:
MFCD00869312
MOL File:
81024-42-2.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-28 08:09:43
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(S)-(-)-METOPROLOL Properties

Melting point 41-43°C
Boiling point 398.647±37.00 °C(Press: 760.00 Torr)(predicted)
Density 1.033±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
storage temp. -20°C Freezer, Under Inert Atmosphere
solubility Chloroform, Methanol
form Solid
pka 9.7
color Light Beige
InChI InChI=1S/C15H25NO3/c1-12(2)16-10-14(17)11-19-15-6-4-13(5-7-15)8-9-18-3/h4-7,12,14,16-17H,8-11H2,1-3H3/t14-/m0/s1
InChIKey IUBSYMUCCVWXPE-AWEZNQCLSA-N
SMILES C(OC1=CC=C(CCOC)C=C1)[C@@H](O)CNC(C)C

(S)-(-)-METOPROLOL price More Price(9)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC TRC-M338780-1MG (S)-Metoprolol 81024-42-2 1mg $248 2026-06-03 Buy
TRC TRC-M338780-10MG (S)-Metoprolol 81024-42-2 10mg $1813 2026-06-03 Buy
Usbiological 017609 S-Metoprolol 81024-42-2 1mg $523 2026-06-03 Buy
aablocks AA008L9F (2S)-1-[4-(2-Methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]-2-propanol 81024-42-2 2mg $423 2026-05-28 Buy
aablocks AA008L9F (2S)-1-[4-(2-Methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]-2-propanol 81024-42-2 5mg $967 2026-05-28 Buy
Product number Packaging Price Buy
TRC-M338780-1MG 1mg $248 Buy
TRC-M338780-10MG 10mg $1813 Buy
017609 1mg $523 Buy
AA008L9F 2mg $423 Buy
AA008L9F 5mg $967 Buy

(S)-(-)-METOPROLOL Chemical Properties, Uses, Production

Chemical Properties

Light Beige Low Melting Solid

Uses

(S)-Enantiomer of Metoprolol. Antihypertensive; antianginal; antiarrhythmic (class II).

Pharmaceutical Applications

Clinical experience with chirally pure (S)-(-)-metoprolol at half the dose of racemate has shown it to be as effective as racemate in the treatment of patients with hypertension and angina. S-metoprolol has been shown to be effective and well-tolerated in patients with coexisting diabetes, COPD, and hyperlipidaemia. This confirms higher cardioselectivity of S-metoprolol in clinical settings.[1]

References

[1] Dasbiswas, A., Shinde, S., & Dasbiswas, D. (2008). S-metoprolol: the 2008 clinical review. Journal of the Indian Medical Association, 106 4, 259–262. https://pubmed.ncbi.nlm.nih.gov/18828349/

(S)-(-)-METOPROLOL Preparation Products And Raw materials

Raw materials

Preparation Products

(S)-(-)-METOPROLOL Suppliers

Global Suppliers ( 61)
Supplier Tel Email Country ProdList Advantage
Chemsky（shanghai）International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
Artis Chemistry (Shanghai) Co. Ltd. 86-21-60936353 China 335 58
Cato Research Chemicals Inc. 020-81960175 min.he@cato-chem.com China 1949 55
Quality Control Solutions Ltd. 0755-66853366 13670046396 orders@qcsrm.com China 18188 56
Wuxi Zhongkun Biochemical Technology Co., Ltd. 0510-85629785 18013409632; sales@reading-chemicals.com China 15165 58
Shanghai Kewel Chemical Co., Ltd. 021-64609169 18901607656 greensnown@163.com China 9883 50
Nanjing XiZe Biotechnology CO., Ltd. 025-66023220 15250997978 1511893459@qq.com China 4777 55
BOC Sciences 16314854226 info@bocsci.com United States 9909 65
Hubei Yangxin Medical Technology Co., Ltd. 15374522761 3003392093@yongstandards.com China 9995 55
PI & PI BIOTECH INC. +86-13602409664 +86-17788709170 Sales@pipitech.com China 2644 58
Supplier Advantage
Chemsky（shanghai）International Co.,Ltd. 50
Artis Chemistry (Shanghai) Co. Ltd. 58
Cato Research Chemicals Inc. 55
Quality Control Solutions Ltd. 56
Wuxi Zhongkun Biochemical Technology Co., Ltd. 58
Shanghai Kewel Chemical Co., Ltd. 50
Nanjing XiZe Biotechnology CO., Ltd. 55
BOC Sciences 65
Hubei Yangxin Medical Technology Co., Ltd. 55
PI & PI BIOTECH INC. 58

View Latest Price from (S)-(-)-METOPROLOL manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(S)-(-)-METOPROLOL pictures 2025-11-14 (S)-(-)-METOPROLOL
81024-42-2
 $800.00-8000.00 1g 98%+ 1000kg Hinova Pharma

81024-42-2 ((S)-(-)-METOPROLOL) Related Search:

(R)-(+)-METOPROLOL 1-(4-(2-Methoxyethyl)phenoxy)-3-(oxiran-2-ylMethoxy)propan-2-ol Metoprolol tartrate Metoprolol LEVOBETAXOLOL
O-Desmethyl Metoprolol (S)-(-)-METOPROLOL Metoprolol tartrate imp. E (EP): (2RS)-1-[2-(2-methoxyethyl)-phenoxy]-3-[(1-methylethyl)amino]propan-2-ol Metoprolol tartrate imp. J (EP): 1-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]-3-[4-(2-methoxyethyl)phenoxy]propan-2-ol Metoprolol tartrate imp. O (EP): 1,1'-[(1-methylethyl)imino]bis-[3-[4-(2-methoxyethyl)phenoxy]propan-2-ol]
Metoprolol succinate imp. D (EP): 3-[4-(2-methoxyethyl)phenoxy]propan-1,2-diol mm(CRM standard) Metoprolol tartrate imp. M (EP) as dihydrochloride: 1,3-bis[(1-methylethyl)amino]propan-2-ol dihydrochloride Metoprolol tartrate imp. B (EP): 4-(2-methoxyethyl)phenol mm(CRM standard) Metoprolol tartrate imp. F (EP): (2RS)-1-[(1-methylethyl)amino]-3-phenoxypropan-2-ol Metoprolol succinate imp. O (EP): 3,3'-isopropyliminobis{1-[4-(2-methoxyethyl)phenoxy]-propan-2-ol} mm(CRM standard)
Metoprolol tartrate imp. H (EP): 1-[4-(2-hydroxyethyl)phenoxy]-3-isopropylaminopropan-2-ol mm(CRM standard) Metoprolol succinate imp. H (EP): 1-[4-(2-hydroxyethyl)phenoxy]-3-isopropylaminopropan-2-ol mm(CRM standard) Metoprolol tartrate imp. E (EP): (2RS)-1-[2-(2-methoxyethyl)phenoxy]-3-(isopropylamino)propan-2-ol mm(CRM standard)

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(S)-(-)-METOPROLOL Metoprolol S-Isomer 2-Propanol, 1-[4-(2-methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]-, (2S)- (9CI) 2-Propanol, 1-[4-(2-methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]-, (S)- (2S)-1-[4-(2-Methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]-2-propanol [(2S)-1-[4-(2-Methoxyethyl)phenoxy]-3-[(1-methylethyl)-amino]propan-2-ol (S)-1-(isopropylamino)-3-(4-(2-methoxyethyl)phenoxy)propan-2-ol (2S)-1-[4-(2-methoxyethyl)phenoxy]-3-(propan-2-ylamino)propan-2-ol 2-Propanol, 1-[4-(2-methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]-, (2S)- Metoprolol Impurity 28 (S)-(-)-METOPROLOL USP/EP/BP Metoprolol Impurity 5(S)-Metoprolol Metoprolol EP Impurity 18 81024-42-2 Amine Aromatics Chiral Reagents Intermediates & Fine Chemicals Pharmaceuticals API Reference Standard