DBCO-S-S-PEG3-Biotin
- CAS No.
- 1430408-09-5
- Chemical Name:
- DBCO-S-S-PEG3-Biotin
- Synonyms
- CAS_1430408-09-5;Biotin-PEG3-SS-DBCO;DBCO-S-S-PEG3-Biotin;Disulfide Biotin DBCO (CCT-A112);Dibenzocyclooctyne-S-S-PEG3-Biotin;inhibit,PROTAC Linkers,DBCO-S-S-PEG-3-biotin,Inhibitor,DBCOSSPEG3biotin,DBCO S S PEG3 biotin;11,12-Didehydro-N-[25-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-7,21-dioxo-11,14,17-trioxa-3,4-dithia-8,20-diazapentacos-1-yl]-γ-oxodibenz[b,f]azocine-5(6H)-butanamide;Dibenz[b,f]azocine-5(6H)-butanamide, 11,12-didehydro-N-[25-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-7,21-dioxo-11,14,17-trioxa-3,4-dithia-8,20-diazapentacos-1-yl]-γ-oxo-;N-[24-(11,12-Didehydrodibenzo[b,f]azocin-5(6H)-yl)-13,21,24-trioxo-3,6,9-trioxa-16,17-dithia-12,20-diazatetracos-1-yl]-5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamide
- CBNumber:
- CB13062468
- Molecular Formula:
- C42H56N6O8S3
- Molecular Weight:
- 869.12
- MDL Number:
- MFCD28334542
- MOL File:
- 1430408-09-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
DBCO-S-S-PEG3-Biotin price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | D5552 | Dibenzocyclooctyne-S-S-PEG3-Biotin | 1430408-09-5 | 25MG | $407 | 2026-04-30 | Buy |
| ChemScene | CS-0114845 | DBCO-S-S-PEG3-biotin ≥95% | 1430408-09-5 | 5mg | $136 | 2026-06-04 | Buy |
| BroadPharm | bp-22453 | DBCO-S-S-PEG3-biotin 95% | 1430408-09-5 | 5MG | $205 | 2026-05-24 | Buy |
| BroadPharm | bp-22453 | DBCO-S-S-PEG3-biotin 95% | 1430408-09-5 | 25MG | $442 | 2026-05-24 | Buy |
| BroadPharm | bp-22453 | DBCO-S-S-PEG3-biotin 95% | 1430408-09-5 | 100MG | $1549 | 2026-05-24 | Buy |
DBCO-S-S-PEG3-Biotin Chemical Properties, Uses, Production
Description
DBCO-S-S-PEG3-biotin is a cleavable reagent for introduction of a biotin moiety to azide-containing biomolecules using copper-free Click Chemistry. PEG spacer arm provides better solubility to the labeled molecules in aqueous media. The disulfide bond in this linker can be cleaved using reducing agents such as DTT, BME and TCEP.
Uses
DBCO-S-S-PEG3-biotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DBCO-S-S-PEG3-biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
DBCO-S-S-PEG3-Biotin Preparation Products And Raw materials
Raw materials
Preparation Products
DBCO-S-S-PEG3-Biotin Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TOKYO CHEMICAL INDUSTRY CO., LTD. | 03-36680489 | Sales-JP@TCIchemicals.com | Japan | 28364 | 80 |
| TCI Europe | 320-37350700 | sales@tcieurope.eu | Europe | 23654 | 75 |
| TCI AMERICA | 800-4238616 | sales@tciamerica.com | Americas | 23636 | 75 |
| Shanghai Macklin Biochemical Co.,Ltd. | 15221275939 15221275939 | shenlinxing@macklin.cn | China | 15775 | 55 |
| Borenpharm Co., Ltd | 027-65563561 | sales@borenpharm.com | China | 1245 | 55 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Jinan elephant international trading co., LTD | 13006575422@163.com | China | 6347 | 58 | |
| Xi'an Confluore Biological Technology Co., Ltd. | +86-156-80926068 +86-15680926068 | 1924344760@qq.com | China | 4229 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Wuhan Borenpharm Co., Ltd | 027-65563561 18717150066 | 3207347307@qq.com | CHINA | 1238 | 58 |
View Latest Price from DBCO-S-S-PEG3-Biotin manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-15 | DBCO-S-S-PEG3-biotin
1430408-09-5
|
$36.00-128.00 | 95.00% | 10g | TargetMol Chemicals Inc. | ||
 |
2025-06-07 | Biotin-PEG3-SS-DBCO
1430408-09-5
|
5mg | >98.00% | 50 | Xian confluore Biological Technology Co., Ltd. |
-
- DBCO-S-S-PEG3-biotin
1430408-09-5
- $36.00-128.00
- 95.00%
- TargetMol Chemicals Inc.
-
- Biotin-PEG3-SS-DBCO
1430408-09-5
- $0.00
- >98.00%
- Xian confluore Biological Technology Co., Ltd.
