ChemicalBook >> CAS DataBase List >>beta-Phenyl-1,N2-ethenoguanosine-3',5'-cyclic monophosphate sodium salt
beta-Phenyl-1,N2-ethenoguanosine-3',5'-cyclic monophosphate sodium salt
- CAS No.
- 78080-27-0
- Chemical Name:
- beta-Phenyl-1,N2-ethenoguanosine-3',5'-cyclic monophosphate sodium salt
- Synonyms
- PET-CGMP;PET-CGMP SODIUM SALT;BETA-PHENYL-1,N2-ETHENOGUANOSINE-3',5'-MONOPHOSPHATE SODIUM SALT;β-Phenyl-1,N2-ethenoguanosine 3μ,5μ-monophosphate sodium salt;beta-Phenyl-1,N2-ethenoguanosine-3',5'-cyclic monophosphate sodium salt;?phenyl-1,n?ethenoguanosine-3’,5’-cyclicmonophosphate(pet-cgmp),sodiumsalt;9H-Imidazo[1,2-a]purin-9-one, 3,4-dihydro-6-phenyl-3-(3,5-O-phosphinico-β-D-ribofuranosyl)-;9H-Imidazo[1,2-a]purin-9-one,3,4-dihydro-6-phenyl-3-(3,5-O-phosphinico-b-D-ribofuranosyl)- (9CI);((2R,3R,4S,5R)-4-Acetoxy-5-(2-amino-6-chloro-9H-purin-9-yl)-3-fluorotetrahydrofuran-2-yl)methyl 4-methylbenzoate;3-[(4aR,6R,7R,7aS)-7-hydroxy-2-oxido-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]-6-phenyl-5H-imidazo[1,2-a]purin-9-one
- CBNumber:
- CB1308020
- Molecular Formula:
- C18H16N5O7P
- Molecular Weight:
- 445.32
- MDL Number:
- MFCD04118064
- MOL File:
- 78080-27-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-09-12 18:49:10
| Boiling point | 932.4±75.0 °C(Predicted) |
|---|---|
| Density | 2.06±0.1 g/cm3(Predicted) |
| storage temp. | -70°C |
| solubility | H2O: ~10 mmol |
| form | solid |
| pka | 1.05±0.60(Predicted) |
| color | white |
| Water Solubility | H2O: ~10mmol |
| InChIKey | IGIOCJJIGJLGKR-TZNCIMHNSA-M |
| SMILES | [Na+].O[C@@H]1[C@@H]2OP([O-])(=O)OC[C@H]2O[C@H]1n3cnc4C(=O)N5C=C(NC5=Nc34)c6ccccc6 |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| PPE | Eyeshields, Gloves, type N95 (US) |
|---|---|
| WGK Germany | 3 |
| Storage Class | 11 - Combustible Solids |
beta-Phenyl-1,N2-ethenoguanosine-3',5'-cyclic monophosphate sodium salt price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | P0622 | PET-cGMP ≥98% (HPLC), solid | 78080-27-0 | 1vial | $656 | 2023-06-20 | Buy |
| Biosynth | DDA08027 | PET-cGMP | 78080-27-0 | 5mg | $419.8 | 2026-06-04 | Buy |
| Biosynth | DDA08027 | PET-cGMP | 78080-27-0 | 10mg | $671.5 | 2026-06-04 | Buy |
| Biosynth | DDA08027 | PET-cGMP | 78080-27-0 | 25mg | $1259.25 | 2026-06-04 | Buy |
| Biosynth | DDA08027 | PET-cGMP | 78080-27-0 | 50mg | $2015.5 | 2026-06-04 | Buy |
beta-Phenyl-1,N2-ethenoguanosine-3',5'-cyclic monophosphate sodium salt Chemical Properties, Uses, Production
Uses
PET-cGMP is a cyclic guanosine monophosphate analog and an effective selective agonist of PKG I, the EC50 of PET-cGMP for PKG Iβ is 3.8 nM, while for PKG II, it's 193 nM[1].
Biochem/physiol Actions
cGMP-dependent protein kinase (PKG I and PKG II) activator. Potent membrane permeant activator of both isozymes I α and I β of cGMP-dependent protein kinase. Common stimulators such as 8-Br-cGMP or 8-pCPT-cGMP mainly activate kinase subtype Iα.
References
[1] James C Campbell, et al. Structural Basis of Analog Specificity in PKG I and II. ACS Chem Biol. 2017 Sep 15;12(9):2388-2398. DOI:10.1021/acschembio.7b00369
beta-Phenyl-1,N2-ethenoguanosine-3',5'-cyclic monophosphate sodium salt Preparation Products And Raw materials
Raw materials
Preparation Products
beta-Phenyl-1,N2-ethenoguanosine-3',5'-cyclic monophosphate sodium salt Suppliers
Global Suppliers ( 10)
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51389 | 80 |
| BOC Sciences | 16314854226 | inquiry@bocsci.com | United States | 9713 | 58 |
| Shanghai meikai technology co., ltd | 021-68689288 15300790979 | info@mkbio.com.cn | China | 9988 | 58 |
| Supplier | Advantage |
|---|---|
| Sigma-Aldrich | 80 |
| BOC Sciences | 58 |
| Shanghai meikai technology co., ltd | 58 |
78080-27-0 (beta-Phenyl-1,N2-ethenoguanosine-3',5'-cyclic monophosphate sodium salt) Related Search:
BETA-PHENYL-1,N2-ETHENOGUANOSINE-3',5'-MONOPHOSPHATE SODIUM SALT
PET-CGMP
PET-CGMP SODIUM SALT
?phenyl-1,n?ethenoguanosine-3’,5’-cyclicmonophosphate(pet-cgmp),sodiumsalt
β-Phenyl-1,N2-ethenoguanosine 3μ,5μ-monophosphate sodium salt
3-[(4aR,6R,7R,7aS)-7-hydroxy-2-oxido-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]-6-phenyl-5H-imidazo[1,2-a]purin-9-one
9H-Imidazo[1,2-a]purin-9-one,3,4-dihydro-6-phenyl-3-(3,5-O-phosphinico-b-D-ribofuranosyl)- (9CI)
9H-Imidazo[1,2-a]purin-9-one, 3,4-dihydro-6-phenyl-3-(3,5-O-phosphinico-β-D-ribofuranosyl)-
((2R,3R,4S,5R)-4-Acetoxy-5-(2-amino-6-chloro-9H-purin-9-yl)-3-fluorotetrahydrofuran-2-yl)methyl 4-methylbenzoate
beta-Phenyl-1,N2-ethenoguanosine-3',5'-cyclic monophosphate sodium salt
78080-27-0
C18H15N5O7PNa
C18H15N5NaO7P
