Guanethidine hemisulfate
- CAS No.
- 60-02-6
- Chemical Name:
- Guanethidine hemisulfate
- Synonyms
- GUANETHIDINE SULFATE;guanethidine sulphate;Iporal;octadin;su-5864;Oktadin;octadine;Guethine;isobarin;nsc-29863
- CBNumber:
- CB1309441
- Molecular Formula:
- C10H22N4.1/2H2O4S
- Molecular Weight:
- 494.7
- MDL Number:
- MFCD00079332
- MOL File:
- 60-02-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 255-265°C |
|---|---|
| Density | 1.1052 (rough estimate) |
| refractive index | 1.7400 (estimate) |
| storage temp. | Hygroscopic, -20°C Freezer, Under Inert Atmosphere |
| solubility | Methanol (Slightly), Water (Slightly) |
| form | Solid |
| color | White |
| Merck | 4560 |
| Stability | Hygroscopic |
| CAS DataBase Reference | 60-02-6 |
| FDA UNII | 8AQ60474G9 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H319-H315-H302-H335 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P-P264-P270-P301+P312-P330-P501 |
| Safety Statements | 24/25 |
| RTECS | MF3240000 |
Guanethidine hemisulfate price More Price(14)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 012989 | Guanethidine Hemisulfate ~90% | 60-02-6 | 1g | $453 | 2026-06-03 | Buy |
| Biosynth | FG23707 | Guanethidine hemisulfate | 60-02-6 | 100mg | $150 | 2026-06-04 | Buy |
| Biosynth | FG23707 | Guanethidine hemisulfate | 60-02-6 | 250mg | $160 | 2026-06-04 | Buy |
| Biosynth | FG23707 | Guanethidine hemisulfate | 60-02-6 | 500mg | $260 | 2026-06-04 | Buy |
| Biosynth | FG23707 | Guanethidine hemisulfate | 60-02-6 | 1000mg | $480 | 2026-06-04 | Buy |
Guanethidine hemisulfate Chemical Properties, Uses, Production
Chemical Properties
White Solid
Originator
Ismelin,Ciba,US,1960
Uses
Antihypertensive; antiglaucoma
Definition
ChEBI: A organic sulfate salt composed of two molecules of guanethidine and one of sulfuric acid.
Manufacturing Process
13.6 grams of chloroacetyl guanide is added while stirring to a solution of 22.6 grams of heptamethylene imine in 200 ml of benzene. After warming for 1 hour, and then cooling, the solution is filtered and the filtrate concentrated under reduced pressure. The residue, containing the 2-(1-N,N-heptamethylene-imino)-aceticacid guanide, is suspended in tetrahydrofuran and added to a refluxing solution of 6 grams of lithium aluminum hydride in tetrahydrofuran. After completion of the reaction, the excess of lithium aluminum hydride is decomposed by adding water, then aqueous sodium hydroxide. The solid material is filtered off, the filtrate is acidified with sulfuric acid and the 2-(1-N,N-heptamethylene-imino)-ethyl-guanidine sulfate can be recovered and recrystallized from aqueous ethanol, MP 276° to 281°C (with decomposition).
Therapeutic Function
Antihypertensive
Guanethidine hemisulfate Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 9920 | 65 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29985 | 65 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +86-189 4982 3763 | sales@tnjchem.com | China | 34526 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 17705817739 | info@dycnchem.com | China | 52493 | 58 |
| Suizhou Jiake Biological Engineering Co., Ltd. | 0722-3632989 18008664499 | 2286801987@qq.com | China | 106 | 58 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8137 | 58 |
| LGC Science (Shanghai) Ltd. | 17717235263 | offer.de@lgcgroup.com | China | 19036 | 58 |
View Latest Price from Guanethidine hemisulfate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-07-02 | guanethidine sulfate
60-02-6
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd |
-
- guanethidine sulfate
60-02-6
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
