FSL-1 lipoprotein, synthetic
- CAS No.
- 322455-70-9
- Chemical Name:
- FSL-1 lipoprotein, synthetic
- Synonyms
- (R)-FSL-1;FSL-1 ，S8428;FSL-1 >=80% (HPLC);FSL-1, TLR2/6 agonist;FSL-1 lipoprotein, synthetic;L-Phenylalanine, S-[2,3-bis[(1-oxohexadecyl)oxy]propyl]-L-cysteinylglycyl-L-α-aspartyl-L-prolyl-L-lysyl-L-histidyl-L-prolyl-L-lysyl-L-seryl-
- CBNumber:
- CB13143802
- Molecular Formula:
- C84H140N14O18S
- Molecular Weight:
- 1666.1584
- MDL Number:
- MFCD29049541
- MOL File:
- 322455-70-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Boiling point | 1659.8±65.0 °C(Predicted) |
|---|---|
| Density | 1+-.0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | Soluble in DMSO |
| form | powder |
| pka | 3.46±0.10(Predicted) |
| color | Colorless |
| Water Solubility | H2O: soluble |
| Sequence | Ser-(2,3-Bispalmitoyloxypropyl)-Cys-Gly-Asp-Pro-Lys-His-Pro-Lys-Ser-Phe |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
FSL-1 lipoprotein, synthetic price More Price(17)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML1420 | FSL-1 ≥80% (HPLC) | 322455-70-9 | 100 μg | $336 | 2026-04-30 | Buy |
| Cayman Chemical | 24220 | FSL-1 ≥95% | 322455-70-9 | 500μg | $75 | 2021-12-16 | Buy |
| Cayman Chemical | 24220 | FSL-1 ≥95% | 322455-70-9 | 1mg | $143 | 2021-12-16 | Buy |
| Biosynth | XMA45570 | FSL-1 | 322455-70-9 | 1mg | $4595.03 | 2026-06-05 | Buy |
| ChemScene | CS-0107456 | FSL-1 99.22% | 322455-70-9 | 1mg | $314 | 2026-06-04 | Buy |
FSL-1 lipoprotein, synthetic Chemical Properties, Uses, Production
Uses
FSL-1, a bacterial-derived toll-like receptor 2/6 (TLR2/6) agonist, enhances resistance to experimental HSV-2 infection[1][2].
Biological Activity
FSL-1 (Pam2CGDPKHPKSF) is a synthetic lipoprotein th at acts as a Toll-like Receptor 2/6 (TLR2/6) agonist and activator of nuclear transcription factor NF-KB. FSL-1 is based on the N-terminal part of the 44-kDa lipoprotein LP44 of Mycoplasma salivarium. FSL-1 showed higher stimulatory activity than MALP-2 in its ability to induce TNF-α production in macrophages and NF-KB in TLR2/TLR6 transfected HEK293 cells.', 'FSL-1 is a bacterial-derived toll-like receptor 2/6 agonist. It is capable of increasing resistance to herpes simplex virus type 2 (HSV-2) infection.
IC 50
TLR2; TLR6
storage
+4°C
References
[1] William A Rose 2nd, et al. FSL-1, a bacterial-derived toll-like receptor 2/6 agonist, enhances resistance to experimental HSV-2 infection. Virol J. 2009 Nov 10;6:195. DOI:10.1186/1743-422X-6-195
[2] Rasheed Ahmad, et al. FSL-1 induces MMP-9 production through TLR-2 and NF-κB /AP-1 signaling pathways in monocytic THP-1 cells. Cell Physiol Biochem. 2014;34(3):929-42. DOI:10.1159/000366310
FSL-1 lipoprotein, synthetic Preparation Products And Raw materials
Raw materials
Preparation Products
FSL-1 lipoprotein, synthetic Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 9920 | 65 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Beijing Solarbio Science & Tecnology Co., Ltd. | 17801761073 18101056239 | 3193328036@qq.com | China | 28150 | 68 |
| Nanjing Leon Biological Technology Co., Ltd. | 025-84523390 -127; 17705183659 | sales@njleonbiotech.com | China | 5501 | 55 |
| Nanjing Peptide Biotech Ltd. | 025-58361106-805 15951641583 | zhao.xu@njpeptide.com | China | 9976 | 55 |
| Hangzhou Peptidego Biotech Co.,Ltd. | 0571-87213919 15967184799 | Eric@peptidego.com | China | 7872 | 58 |
| Nanjing Meihao Pharmaceutical Technology Co., Ltd. | meitaochem@126.com | meitaochem@126.com | China | 19087 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 | sales@sarms4muscle.com | China | 10378 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
| Wuxi Helen Biotechnology Co., Ltd., | 0510-85629785 18013409632 | sales@reading-chemicals.com | China | 14072 | 58 |
