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ChemicalBook >> CAS DataBase List >>1-[[(6R,7R)-7-[[(2Z)-(2-Amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]pyridinium chloride monohydrochloride

1-[[(6R,7R)-7-[[(2Z)-(2-Amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]pyridinium chloride monohydrochloride

1-[[(6R,7R)-7-[[(2Z)-(2-Amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]pyridinium chloride monohydrochloride Structure
1-[[(6R,7R)-7-[[(2Z)-(2-Amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]pyridinium chloride monohydrochloride structure
CAS No.
73547-70-3
Chemical Name:
1-[[(6R,7R)-7-[[(2Z)-(2-Amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]pyridinium chloride monohydrochloride
Synonyms
CEFTAZIDIME DIHYDROCHLORIDE;2-(2-Aminothiazol-4-yl)-2-;Ceftazidine Dihydrochloride;Ceftazidime N-1 Intermediate;3-CHLORO-4-FLUOROBENZYLAMINE,98%;Ceftazidime Dihydrochloride DISCONTINUED. Please see C244100 or C244128;1-(((6R,7R)-7-((Z)-2-(2-Aminothiazol-4-yl)-2-(((2-carboxypropan-2-yl)oxy)imino)acetamido)-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl)methyl)pyridin-1-ium chloride hydrochloride;1-[[(6R,7R)-7-[[(2Z)-(2-Amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]pyridinium chloride monohydrochloride;(1-{[(6R,7R)-7-[2-(2-aMino-1,3-thiazol-4-yl)-2-[(1-carboxy-1-Methylethoxy)iMino]acetaMido]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]Methyl}pyridin-1-iuM-2-yl)chloranuide hydrochloride;1-{[(6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}pyridinium chloride hydrochloride (1:1:1)
CBNumber:
CB1319833
Molecular Formula:
C22H23N6O7S2.ClH.Cl
Molecular Weight:
619.5
MDL Number:
MFCD06658281
MOL File:
73547-70-3.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-27 23:31:00
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1-[[(6R,7R)-7-[[(2Z)-(2-Amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]pyridinium chloride monohydrochloride Properties

Density 1.185g/cm3 at 20℃
vapor pressure 18-1800Pa at 20℃
form Solid:particulate/powder
InChIKey JLZLIGALAZXURA-NINLSHECNA-N
SMILES C(C1=C(CS[C@]2([H])[C@H](NC(=O)/C(/C3N=C(N)SC=3)=N\OC(C)(C)C(=O)O)C(=O)N12)C[N+]1=CC=CC=C1)(=O)O.[Cl-].Cl |&1:5,7,r|
LogP -6.028--3.36
CAS DataBase Reference 73547-70-3(CAS DataBase Reference)
FDA UNII 8ORW199D1G

SAFETY

Risk and Safety Statements

Symbol(GHS)  Health Hazard (GHS08)Exclamation Mark (GHS07)
GHS08,GHS07
Signal word  Danger
Hazard statements  H319-H412-H317-H334
Precautionary statements  P264-P280-P305+P351+P338-P337+P313P-P261-P285-P304+P341-P342+P311-P501-P261-P272-P280-P302+P352-P333+P313-P321-P363-P501-P273-P501
REACH Registrations Active

1-[[(6R,7R)-7-[[(2Z)-(2-Amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]pyridinium chloride monohydrochloride price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
aablocks AA00FA0L Ceftazidime Dihydrochloride ≥95% 73547-70-3 250mg $29 2026-05-28 Buy
aablocks AA00FA0L Ceftazidime Dihydrochloride ≥95% 73547-70-3 1g $86 2026-05-28 Buy
aablocks AA00FA0L Ceftazidime Dihydrochloride ≥95% 73547-70-3 5g $286 2026-05-28 Buy
aablocks AA00FA0L Ceftazidime Dihydrochloride ≥95% 73547-70-3 25g $1029 2026-05-28 Buy
Crysdot CD11065023 Ceftazidime dihydrochloride 97% 73547-70-3 1g $178 2026-05-26 Buy
Product number Packaging Price Buy
AA00FA0L 250mg $29 Buy
AA00FA0L 1g $86 Buy
AA00FA0L 5g $286 Buy
AA00FA0L 25g $1029 Buy
CD11065023 1g $178 Buy

1-[[(6R,7R)-7-[[(2Z)-(2-Amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]pyridinium chloride monohydrochloride Chemical Properties, Uses, Production

Preparation

Currently, two different methods for preparing ceftazidime are reported in the literature: The first method uses 7-aminocephalosporanic acid (7-ACA) as the starting core, reacting it with pyridine in the presence of trimethyliodosilane (TMSI) to obtain 7-APCA dihydrochloride. This dihydrochloride reacts with the active ester of the ceftazidime side chain acid to obtain ceftazidime tert-butyl ester. This tert-butyl ester is then hydrolyzed to obtain ceftazidime pentahydrate, which is mixed with sodium carbonate to prepare the injectable active pharmaceutical ingredient. The second method uses 7-phenylacetamide-3-chloromethylcephalosporanic acid p-methoxybenzyl ester (GCLE) as the starting core, reacting it with potassium iodide to obtain the ceftazidime intermediate 7-phenylacetamido-3-iodomethyl-3-cephalosporin-4-carboxylic acid p-methoxybenzyl ester. This intermediate undergoes a series of reactions, including nucleophilic substitution, with pyridine to obtain the target product. 1-[[(6R,7R)-7-[[(2Z)-(2-Amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]pyridinium chloride monohydrochloride can be used as a raw material for the preparation of ceftazidime formulations.

Uses

6S,7R-Ceftazidime Isomer is an impurity of Ceftazidime (C244100). Ceftazidime Third generation cephalosporin antibiotic. Antibacterial.

1-[[(6R,7R)-7-[[(2Z)-(2-Amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]pyridinium chloride monohydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

1-[[(6R,7R)-7-[[(2Z)-(2-Amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]pyridinium chloride monohydrochloride Suppliers

Global Suppliers ( 116)
Supplier Tel Email Country ProdList Advantage
XiaoGan ShenYuan ChemPharm co,ltd 15527621225; 15527621225 1791901229@qq.com China 6741 52
Zeshan Cheng New Materials (Wuhan) Co., Ltd 17786425391 jim@zeshancheng.com China 314 58
Beijing Ouhe Technology Co., Ltd 13552068683 13522913783 2355560935@qq.com China 11777 60
Beijing HuaMeiHuLiBiological Chemical 010-56205725 waley188@sohu.com China 12323 58
Finetech Industry Limited 027-87465837 19945049750 sales@finetechnology-ind.com China 9331 58
Shanghai Macklin Biochemical Co.,Ltd. 15221275939 15221275939 shenlinxing@macklin.cn China 15775 55
Credit Asia Chemical Co., Ltd. +86 (21) 61124340 China 9739 58
Runze Pharmaceutical Suzhou Co., Ltd. +86-512-62831367 13140980067 sales1@szrz.com.cn China 37 58
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Cangzhou Enke Pharma-tech Co., Ltd. 0317-5296180 15533709196 enkepharma@126.com China 2495 55
Supplier Advantage
XiaoGan ShenYuan ChemPharm co,ltd 52
Zeshan Cheng New Materials (Wuhan) Co., Ltd 58
Beijing Ouhe Technology Co., Ltd 60
Beijing HuaMeiHuLiBiological Chemical 58
Finetech Industry Limited 58
Shanghai Macklin Biochemical Co.,Ltd. 55
Credit Asia Chemical Co., Ltd. 58
Runze Pharmaceutical Suzhou Co., Ltd. 58
Shanghai YuanYe Biotechnology Co., Ltd. 60
Cangzhou Enke Pharma-tech Co., Ltd. 55

View Latest Price from 1-[[(6R,7R)-7-[[(2Z)-(2-Amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]pyridinium chloride monohydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Ceftazidime dihydrochloride pictures 2019-08-08 Ceftazidime dihydrochloride
73547-70-3
 $3.00 1KG 99% 100kg Career Henan Chemical Co

73547-70-3 (1-[[(6R,7R)-7-[[(2Z)-(2-Amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]pyridinium chloride monohydrochloride) Related Search:

CeftazidiMe Ceftazidime pentahydrate 1-[2-(Dimethylamino)ethyl]-1H-tetrazole-5-thiol Ceftazidime sterile(sodium carbonate) 7(R)-amino-3-(1-pyridiniomethyl)-3-cephem-4-carboxylic acid chloride monohydrochloride
2-Mercaptobenzothiazolyl-(Z)-(2-aminothiazol-4-yl)-2-(tert-butoxycarbonyl) isopropoxyiminoacetate TAEM (Z)-2-Amino-alpha-[1-(tert-butoxycarbonyl)]-1-methylethoxyimino-4-thiazolacetic acid 3-Chloro-4-fluorobenzylamine 1-[[(6R,7R)-7-[[(2Z)-(2-Amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]pyridinium chloride monohydrochloride
1-Carboxy-1-methylethoxyammonium chloride O-tert-Butylhydroxylamine hydrochloride 2-(Isopropylideneaminooxy)propionic acid 3-(Methylamino)azetidine dihydrochloride N-Ethyl-3-azetidinamine dihydrochloride
1-Methyl-azetidin-3-ylamine dihydrochloride 3-Aminoazetidine

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3-CHLORO-4-FLUOROBENZYLAMINE,98% 1-[[(6R,7R)-7-[[(2Z)-(2-Amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]pyridinium chloride monohydrochloride (1-{[(6R,7R)-7-[2-(2-aMino-1,3-thiazol-4-yl)-2-[(1-carboxy-1-Methylethoxy)iMino]acetaMido]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]Methyl}pyridin-1-iuM-2-yl)chloranuide hydrochloride Ceftazidine Dihydrochloride 1-(((6R,7R)-7-((Z)-2-(2-Aminothiazol-4-yl)-2-(((2-carboxypropan-2-yl)oxy)imino)acetamido)-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl)methyl)pyridin-1-ium chloride hydrochloride Ceftazidime N-1 Intermediate Ceftazidime Dihydrochloride DISCONTINUED. Please see C244100 or C244128 1-{[(6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}pyridinium chloride hydrochloride (1:1:1) CEFTAZIDIME DIHYDROCHLORIDE 2-(2-Aminothiazol-4-yl)-2- 73547-70-3 103777-53-9 C22H24Cl2N6O7S2 C22H22N6O7S22HCl C22H23N6O7S2ClHCl