Benzyloxy carbonyl-PEG3-acid
- CAS No.
- 2100306-73-6
- Chemical Name:
- Benzyloxy carbonyl-PEG3-acid
- Synonyms
- Benzyloxy carbonyl-PEG3-acid;Benzyloxy carbonyl-PEG3-C2-acid;3-Oxo-1-phenyl-2,6,9,12-tetraoxapentadecan-15-oic acid;4,7,10,14-Tetraoxapentadecanoic acid, 13-oxo-15-phenyl-
- CBNumber:
- CB13373586
- Molecular Formula:
- C17H24O7
- Molecular Weight:
- 340.37
- MDL Number:
- MFCD30723204
- MOL File:
- 2100306-73-6.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P280-P305+P351+P338 |
Benzyloxy carbonyl-PEG3-acid price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0115467 | Benzyloxy carbonyl-PEG3-C2-acid ≥98% | 2100306-73-6 | 250mg | $55 | 2026-06-04 | Buy |
| ChemScene | CS-0115467 | Benzyloxy carbonyl-PEG3-C2-acid ≥98% | 2100306-73-6 | 1g | $147 | 2026-06-04 | Buy |
| ChemScene | CS-0115467 | Benzyloxy carbonyl-PEG3-C2-acid ≥98% | 2100306-73-6 | 5g | $514 | 2026-06-04 | Buy |
| Activate Scientific | AS1224 | Benzyloxy carbonyl-PEG3-acid 95% | 2100306-73-6 | 1g | $260 | 2026-06-04 | Buy |
| Activate Scientific | AS1224 | Benzyloxy carbonyl-PEG3-acid 95% | 2100306-73-6 | 5g | $746 | 2026-06-04 | Buy |
Benzyloxy carbonyl-PEG3-acid Chemical Properties, Uses, Production
Description
Benzyloxy carbonyl-PEG3-acid is a PEG linker with a benzyl protecting group and a carboxylic acid moiety. The carboxylic acid can undergo reactions with primary amines in the presence of activators such as EDC and HATU to form stable amide bonds. The benzyl protecting group can be removed via hydrogenolysis. The hydrophilic PEG linker increases the water solubility of the compound.
Uses
Benzyloxy carbonyl-PEG3-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Benzyloxy carbonyl-PEG3-acid Preparation Products And Raw materials
Raw materials
Preparation Products
Benzyloxy carbonyl-PEG3-acid Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jiangsu aikang biomedical research and development co., LTD | 025-58859352 17714375163 | qzhang@aikonchem.com | China | 15525 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Shaanxi Xinyan Bomei Biotechnology Co., Ltd. | 13892832556 | 2440688701@qq.com | China | 1981 | 58 |
| Zhengzhou Akem Chemical Co., Ltd | 13303867194 | 770406999@qq.com | China | 9949 | 58 |
| Shanghai Haohong Scientific Co., Ltd. | 400-8210725 4008210725 | malulu@leyan.com | China | 39718 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | 18143011203 | ET-market@chemextension.com | China | 38923 | 58 |
| Hubei wei shi reagent group ltd., company | 17771898297 13125137661 | 2853877621@qq.com | China | 7992 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| Henan Mengtai Pharmaceutical Technology Co., Ltd | 17634413542 | 1959525201@qq.com | China | 9011 | 58 |
| Science Care Ningbo Co.,Ltd | +86-574-87260203 +86-18368238604 | bd@scningbo.hk | China | 299 | 58 |
