N-BENZOYL-4-PIPERIDONE
- CAS No.
- 24686-78-0
- Chemical Name:
- N-BENZOYL-4-PIPERIDONE
- Synonyms
- 1-BENZOYL-4-PIPERIDONE;NSC 97564;N-BENZOYLPIPERIDONE;N-Benzoylpiperidinone;N-BENZOYL-4-PIPERIDONE;1-Benzoyl-piperidinoine;N-Benzoylpiperidone 98%;N-benzoylpiperidine-one;4-Piperidone, 1-benzoyl-;1-Benzoyl-4-piperidinone
- CBNumber:
- CB1349049
- Molecular Formula:
- C12H13NO2
- Molecular Weight:
- 203.24
- MDL Number:
- MFCD00006189
- MOL File:
- 24686-78-0.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 1-Benzoyl-4-piperidone >97.0%(GC) | B3778 | 5g | $78 |
| 1-Benzoyl-4-piperidone >97.0%(GC) | B3778 | 25g | $311 |
| N-BENZOYL-4-PIPERIDONE 97% | 53630 | 5G | $27 |
| N-BENZOYL-4-PIPERIDONE 97% | 53630 | 25G | $57 |
| N-Benzoylpiperidone | FB142667 | 25g | $336.5 |
| More product size | |||
| Melting point | 55-59 °C (lit.) |
|---|---|
| Boiling point | 158-160 °C/0.2 mmHg (lit.) |
| Density | 1.1255 (rough estimate) |
| refractive index | 1.5440 (estimate) |
| Flash point | >230 °F |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | methylene chloride: soluble |
| form | powder to crystal |
| pka | -1.45±0.20(Predicted) |
| color | White to Light yellow |
| BRN | 158848 |
| InChI | 1S/C12H13NO2/c14-11-6-8-13(9-7-11)12(15)10-4-2-1-3-5-10/h1-5H,6-9H2 |
| InChIKey | NZAXGZYPZGEVBD-UHFFFAOYSA-N |
| SMILES | O=C1CCN(CC1)C(=O)c2ccccc2 |
| CAS DataBase Reference | 24686-78-0(CAS DataBase Reference) |
| FDA UNII | NSA9KD42VW |
| UNSPSC Code | 12352100 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301-H312+H332-H315-H319 | |||||||||
| Precautionary statements | P501-P261-P270-P271-P264-P280-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P310+P330-P302+P352+P312-P304+P340+P312-P405 | |||||||||
| PPE | Eyeshields, Gloves, type N95 (US) | |||||||||
| Hazard Codes | Xi | |||||||||
| Safety Statements | 24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Irritant | |||||||||
| HS Code | 29333999 | |||||||||
| Storage Class | 13 - Non Combustible Solids | |||||||||
| NFPA 704 |
|
N-BENZOYL-4-PIPERIDONE price More Price(39)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | B3778 | 1-Benzoyl-4-piperidone >97.0%(GC) | 24686-78-0 | 5g | $78 | 2024-03-01 | Buy |
| TCI Chemical | B3778 | 1-Benzoyl-4-piperidone >97.0%(GC) | 24686-78-0 | 25g | $311 | 2024-03-01 | Buy |
| AstaTech | 53630 | N-BENZOYL-4-PIPERIDONE 97% | 24686-78-0 | 5G | $27 | 2026-04-30 | Buy |
| AstaTech | 53630 | N-BENZOYL-4-PIPERIDONE 97% | 24686-78-0 | 25G | $57 | 2026-04-30 | Buy |
| Biosynth | FB142667 | N-Benzoylpiperidone | 24686-78-0 | 25g | $336.5 | 2026-06-04 | Buy |
N-BENZOYL-4-PIPERIDONE Chemical Properties,Uses,Production
Chemical Properties
light yellow granular powder or granules
Uses
1-Benzoyl-4-piperidone can be used as starting reagent in the synthesis of fentanyl.
Biochem/physiol Actions
1-Benzoyl-4-piperidone and 1-methyl-4-piperidone reacts with triethyl phosphono-acetate in the presence of excess base and yields both the endocyclic and exocyclic olefins.
Synthesis
4-Piperidone hydrochloride hydrate (7.68 kg) with potassium carbonate (20.7 kg), 0 C., added to water (50 liters), stirred well, then added to dichloromethane (40 liters), and then added dropwise to a solution of benzoyloxycarbonylsuccinimide (12.4 kg) of dichloromethane (80 liters), and the reaction was carried out at room temperature for two hours. The reaction solution was partitioned and the aqueous layer was extracted with dichloromethane (2 x 15 liters), the organic phases were combined, dried over anhydrous sodium sulfate, and concentrated to give 11.5 kg of 1-benzoyl-4-piperidone in the form of a colorless oil.
N-BENZOYL-4-PIPERIDONE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Yanxi Chemical Co., Ltd. | +86-17531190177 | faithe@yan-xi.com | China | 5838 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32997 | 60 |
| Changzhou Ditong Chemical Co.,Ltd | +86-0519-88298848 | info@edengenechem.com | China | 2163 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63645 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10817 | 58 |
| career henan chemical co | +86-0371-86658258 | factory@coreychem.com | China | 29780 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 | contact@fuxinpharm.com | China | 9976 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +86-189 4982 3763 | sales@tnjchem.com | China | 34526 | 58 |
| Hefei Hirisun Pharmatech Co., Ltd | +8615056975894 | shawn@hirisunpharm.com | CHINA | 9897 | 58 |
| CD Chemical Group Limited | +86-13651442114 | info@codchem.com | China | 17253 | 58 |
View Lastest Price from N-BENZOYL-4-PIPERIDONE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-06-20 | N-BENZOYL-4-PIPERIDONE
24686-78-0
|
1kg | 0.99 | 20tons | Hebei Yanxi Chemical Co., Ltd. | ||
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2021-08-12 | N-BENZOYL-4-PIPERIDONE
24686-78-0
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd | ||
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2020-01-09 | N-BENZOYL-4-PIPERIDONE
24686-78-0
|
$1.00 | 1KG | 99% | 200kg | Career Henan Chemical Co |
-

- N-BENZOYL-4-PIPERIDONE
24686-78-0
- $0.00
- 0.99
- Hebei Yanxi Chemical Co., Ltd.
-

- N-BENZOYL-4-PIPERIDONE
24686-78-0
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-

- N-BENZOYL-4-PIPERIDONE
24686-78-0
- $1.00
- 99%
- Career Henan Chemical Co
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