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Tebuconazole

CAS No.
107534-96-3
Chemical Name:
Tebuconazole
Synonyms
TEBUCONAZOL;-ol;ELITE;1-ethanol;(RS)-1-p-Chlorophenyl-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol;LYNX;TERBUCONAZOLE;tebuconazole 97%TC;1-(4-CHLOROPHENYL)-4,4-DIMETHYL-3-(1H-1,2,4-TRIAZOL-1-YLMETHYL)-3-PENTANOL;RAXIL
CBNumber:
CB1350463
Molecular Formula:
C16H22ClN3O
Molecular Weight:
307.82
MDL Number:
MFCD02674797
MOL File:
107534-96-3.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-31 15:25:13

Tebuconazole Properties

Melting point 102-105°C
Boiling point 476.9±55.0 °C(Predicted)
Density 1.25
vapor pressure 1.7 x l0-6 Pa (20 °C)
refractive index 1.5800 (estimate)
Flash point 100 °C
storage temp. Sealed in dry,2-8°C
solubility Chloroform: Slightly Soluble; Methanol: Slightly Soluble
pka 13.70±0.29(Predicted)
form Solid
color White to Almost white
Water Solubility 32 mg/L at 20 ºC
Merck 14,9092
Henry's Law Constant 7.0×104 mol/(m3Pa) at 25℃, HSDB (2015)
Major Application agriculture
cleaning products
cosmetics
environmental
food and beverages
personal care
InChI 1S/C16H22ClN3O/c1-15(2,3)16(10-21,20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3
InChIKey PXMNMQRDXWABCY-UHFFFAOYSA-N
SMILES CC(C)(C)C(CO)(CCc1ccc(Cl)cc1)n2cncn2
LogP 3.700
CAS DataBase Reference 107534-96-3(CAS DataBase Reference)
EWG's Food Scores 3
FDA UNII 401ATW8TRW
NIST Chemistry Reference Tebuconazole(107534-96-3)
EPA Substance Registry System Tebuconazole (107534-96-3)
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)Health Hazard (GHS08)Environment (GHS09)
GHS07,GHS08,GHS09
Signal word  Warning
Hazard statements  H302-H361d-H410
Precautionary statements  P201-P202-P264-P273-P301+P312-P308+P313
PPE dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Hazard Codes  Xn;N,N,Xn
Risk Statements  22-51/53-63
Safety Statements  2-22-36/37-61
RIDADR  UN 3077 9/PG 3
WGK Germany  3
RTECS  XZ4803270
HazardClass  9
PackingGroup  III
HS Code  29339900
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral
Aquatic Acute 1
Aquatic Chronic 1
Repr. 2
Hazardous Substances Data 107534-96-3(Hazardous Substances Data)
Toxicity bird - domestic,LD50,oral,> 1gm/kg (1000mg/kg),Pesticide Manual. Vol. 9, Pg. 785, 1991.
REACH Registrations Inactive
NFPA 704
0
2 0

Tebuconazole price More Price(52)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 43897 Tebuconazole certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland 107534-96-3 50 mg $222 2026-04-30 Buy
Sigma-Aldrich 32013 Tebuconazole PESTANAL 107534-96-3 250mg $77.4 2026-04-30 Buy
Sigma-Aldrich R690236 1-(4-CHLOROPHENYL)-4,4-DIMETHYL-3-(1H-1,2,4-TRIAZOL-1-YLMETHYL)-3-PENTANOL Aldrich 107534-96-3 25mg $172 2023-01-07 Buy
TCI Chemical T2988 Tebuconazole 107534-96-3 1G $99 2026-04-30 Buy
TCI Chemical T2988 Tebuconazole 107534-96-3 5G $339 2026-04-30 Buy
Product number Packaging Price Buy
43897 50 mg $222 Buy
32013 250mg $77.4 Buy
R690236 25mg $172 Buy
T2988 1G $99 Buy
T2988 5G $339 Buy

Tebuconazole Chemical Properties, Uses, Production

Description

Tebuconazole is a trazole fungicide. It is taken up by plants and transported within tissues. It is used as a seed dressing, which works effectively against various smut and bunt diseases of cereals. As foliar spray tebuconazole controls numerous phathogens such as rust species, powdery mildew, and scale in various crops. It is also used to control pests including yellow leaf spot, black spot, net blotch, and Scelerotinia rot.
Tebuconazole can be applied to control above mentioned diseases on cereals (including wheat, barley, oat, rye), grapes, peanuts, vegetables (onions and peas), bananas, sugarcane.

References

[1] http://sitem.herts.ac.uk/aeru/ppdb/en/Reports/610.htm
[2] Pesticide residues in food – 1994 Report sponsored jointly by FAQ and WHO
[3] https://www.efsa.europa.eu/en/efsajournal/pub/3485

Chemical Properties

White Solid

Uses

A triazole fungicide showing potential carcinogenicity

Uses

Fungicide.

Uses

Tebuconazole used as a seed dressing is effective against various smut and bunt diseases of cereals. Used as a spray it controls numerous pathogens in various crops: rust species, powdery mildew, Rhyncosporum secalis, Sqtoria spp., Pyrenophora spp., Fusarium spp. in cereals, Mycosphaerella spp. in bananas, Pucciniu spp. and Sclerufium roIfsii in peanuts.

Uses

Ergosterol biosynthesis inhibitor. Fungicide.

Definition

ChEBI: 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol is a tertiary alcohol that is pentan-3-ol substituted by a 4-chlorophenyl, methyl, methyl, and a 1H-1,2,4-triazol-1-ylmethyl at positions 1, 4, 4 and 3 respectively. It is a member of monochlorobenzenes, a member of triazoles and a tertiary alcohol.

Agricultural Uses

Fungicide, Plant growth regulator: Used as a seed treatment against smuts and bunts of cereals; as a foliar spray against diseases of cereal, peanuts, oilseed rape, grapes, bananas, stone fruit, and pome fruit. Registered for use in EU countries. Registered for use in the U.S.

Trade name

BAY®-HWG 1608; BAYER®-HWG-1608 CORAIL®; ELITE®; FOLICUR®; FOLITRAZOLE®; GAUCHO®; HORIZON®; HWG 1608®; LYNX-1.2®; PREVENTOL® RAXIL (tebuconazole + metalaxyl); SILVACUR®; TEBUJECT®; WOLMAN®; WOODLIFE®

Mechanism of action

Systemic with protective, curative and eradicant action. Disrupts membrane function. Sterol biosynthesis inhibitor.

Synthesis

4H-1,2,4-Triazole-4-ethanol, α-[2-(4-chlorophenyl)ethyl]-α-(1,1-dimethylethyl)-

97821-63-1

Tebuconazole

107534-96-3

To a 250 mL three-necked flask was added 120 g of N,N-dimethylformamide, followed by 40 g of pentaconazole isomer, 2.0 g of potassium hydroxide, and 1.0 g of 3-bromomethyl-1-(4-chlorophenyl)-4,4-dimethyl-3-propanol.The reaction mixture was heated to 150 °C and maintained at this temperature for 4 hours. Sampling and analysis during the reaction showed that the purity of tebuconazole was 99.8% and the isomer content was 0.2%. Upon completion of the reaction, the target product tebuconazole was obtained by removing the solvent, followed by slurry treatment with water and toluene, and finally filtered to give 38.6 g of the target product tebuconazole in 96.5% yield and 98.5% product purity.

Metabolic pathway

Tebuconazole is degraded in soils and does not accumulate. In plants the metabolites were mainly compounds containing triazole, and in mammals tebuconazole was rapidly metabolised and excreted in urine and faeces.

Degradation

Tebuconazole is stable to elevated temperatures. Under sterile conditions it is stable to hydrolysis in water. It is hydrolysed slowly with a DTS0 of >1 year.
Only two products were formed by irradiation of a suspension of tebuconazole in water with UV light (>280 nm). These were the hydrochloride (3) and 1,2,4-triazole (2). The expected product in which chlorine was replaced by hydroxyl could not be isolated. In organic solvents a number of products were formed. Several products (3, 4, 5, 6, 7, 8, 9, 12, 13, 14) were isolated from benzene after 72 hours irradiation (>280 nm). In a number of cases products isolated from photolysis in benzene were formed by reactions in which the solvent participated and involved addition of a benzene molecule (4, 9, 5, 6). On irradiation in methylene chloride and methanol, 4-chloracetophenone (10) and acetophenone (11) were also identified in addition to starting material and 1,2,4-triazole (Wamhoff et al., 1994).

References

[1] Patent: CN106699675, 2017, A. Location in patent: Paragraph 0024-0026
[2] Patent: US4639527, 1987, A

Pesticide Type

Fungicide; Plant Growth Regulator

97821-63-1
107534-96-3
Synthesis of Tebuconazole from 4H-1,2,4-Triazole-4-ethanol, α-[2-(4-chlorophenyl)ethyl]-α-(1,1-dimethylethyl)-
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View Latest Price from Tebuconazole manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Tebuconazole  pictures 2026-07-14 Tebuconazole
100KG 98 200TONS Qingdao Trust Agri Chemical Co.,Ltd
Tebuconazole pictures 2026-07-14 Tebuconazole
107534-96-3
$48.00 99.21% 10g TargetMol Chemicals Inc.
Tebuconazole pictures 2026-05-28 Tebuconazole
107534-96-3
$5.00 10KG 99 % 10000kg Hebei Chuanghai Biotechnology Co,.LTD
  • Tebuconazole pictures
  • Tebuconazole
    107534-96-3
  • $48.00
  • 99.21%
  • TargetMol Chemicals Inc.
  • Tebuconazole pictures
  • Tebuconazole
    107534-96-3
  • $5.00
  • 99 %
  • Hebei Chuanghai Biotechnology Co,.LTD

Tebuconazole Spectrum

(+/-)-alpha-(2-(4-chlorophenyl)ethyl)-alpha-(1,1-dimethylethyl)-1H-1,2,4-triazol-1-ethanol LYNX Lynx 1.2 LYNX(R) MATADOR ELITE(R) FOLICUR folicur 1.2 ec FOLICUR (TM) GWG 1609 hwg 1608 HORIZON 1-(4-CHLOROPHENYL)-4,4-DIMETHYL-3-(1H-1,2,4-TRIAZOL-1-YLMETHYL)-3-PENTANOL 7, (5&alpha -Methyl-cholest-5-en-3&beta 17-Iodo-androsta-5,16-diene-3&beta -[N,N-(4-Phenylurazole)]-3-O-tert-butyldimethylsilyl-chol-6-en-24-al-3&beta 8&alpha 17(20), (5&alpha -OL ~95% 2-Methyl-5&alpha -OL ETHYL ESTER 3-Methoxy-18-methyl-1,3,5(10)-estratrien-17&beta -Pregnane-3-one-20&alpha 3-Methoxy-7&alpha -methyl-estra-2,5(10)-dien-17&beta )-CHOLESTEN-9-19-CYCLO-4, 4, 14&alpha 24, (5&alpha -[N,N-(4-Phenylurazole)]-3&beta -O-tert-butyldimethylsilyloxy-chol-6-en-24-oic Acid Methyl Ester -Cholesta-7,24-diene-3&beta )-ESTREN-3&alpha 17-Methyl-5&alpha -androst-2-eno[2,3-d]isoxazol-17&beta 1-(4-chlorophenyl)-4,4-dimethyl-3-(1,2,4-triazol-1-ylmethyl)-3-pentanol 1-(4-Chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol 97% )-23, 24-BISNOR-CHOLENIC ACID-3&alpha A-[2-(4-CHLOROPHENYL)ETHYL]-A-(1,1-DIMETHYLETHYL)-1H-1,2,4-TRIAZOLE-1-ETHANOL TERBUCONAZOLE TEBUCONAZOLE(R) RAXIL RAXIL(R) (+-)-lethyl) (rs)-1-(4-chlorophenyl)-4,4-dimethyl-3-(1h-1,2,4-triazol-1-ylmethyl)pentan-3 (rs)-1-p-chlorophenyl-4,4-dimethyl-3-(1h-1,2,4-triazol-1-ylmethyl)pentan-3-o 1-dimethylethyl)-1h-1,2,4-triazole-alpha-(2-(4-chlorophenyl)ethyl)-alpha-( 1-ethanol (RS)1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol Silvacur Tebuconazlole FOLICUR, 100MG, NEAT 2 3 4-TRICHLORONITROBENZENE PESTANAL & 1-(4-chlorophenyl)-4,4-dimethyl-3-(1,2,4-triazol-1-ylmethyl)pentan-3-ol Tebuconazol, 1-(4-Chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)-3-pentanol Tebuconazole suspension (RS)-1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazole-1-ylmethyl)pentan-3-ol HGW 1608 1H-1,2,4-Triazole-1-ethanol, .alpha.-2-(4-chlorophenyl)ethyl-.alpha.-(1,1-dimethylethyl)-