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4-HYDROXYMETHYL-5-METHYLIMIDAZOLE

4-HYDROXYMETHYL-5-METHYLIMIDAZOLE Structure
4-HYDROXYMETHYL-5-METHYLIMIDAZOLE structure
CAS No.
29636-87-1
Chemical Name:
4-HYDROXYMETHYL-5-METHYLIMIDAZOLE
Synonyms
Cimetidine Impurity I;4-Methyl-5-imidazolemethanol;Cimetidine Impurity I HCl(EP);5-methyl-1h-imidazole-4-methano;4-Hydoxymethyl-5-methylimidazol;5-methyl-1H-imidazole-4-methanol;4-Methyl-1H-imidazole-5-methanol;5-Hydroxymethyl-4-methylimidazole;4-HYDROXYMETHYL-5-METHYLIMIDAZOLE;5-METHYL-4-HYDROXYMETHYLIMIDAZOLE
CBNumber:
CB1360451
Molecular Formula:
C5H8N2O
Molecular Weight:
112.13
MDL Number:
MFCD00792476
MOL File:
29636-87-1.mol
Last updated:2026-01-13 11:13:55
Product description Number Pack Size Price
Cimetidine Impurity I Pharmaceutical Secondary Standard; Certified Reference Material PHR2260 50mg $916
4-Hydroxymethyl-5-methylimidazole >96.0%(GC)(T) H0976 5g $51
4-Hydroxymethyl-5-methylimidazole >96.0%(GC)(T) H0976 25g $155
4-Hydroxymethyl-5-methylimidazole H005070 100mg $70
4-Hydroxymethyl-5-methylimidazole H005070 50mg $50
More product size
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4-HYDROXYMETHYL-5-METHYLIMIDAZOLE Properties

Melting point 136°C
Boiling point 389.1±27.0 °C(Predicted)
Density 1.231
storage temp. 2-8°C
solubility DMSO (Heated), Methanol (Slightly)
pka 13.62±0.10(Predicted)
form Solid
color White to Off-White
Water Solubility almost transparency
Major Application pharmaceutical small molecule
InChI InChI=1S/C5H8N2O/c1-4-5(2-8)7-3-6-4/h3,8H,2H2,1H3,(H,6,7)
InChIKey AXJZCJSXNZZMDU-UHFFFAOYSA-N
SMILES C1NC(CO)=C(C)N=1
LogP -0.62 at 23℃ and pH8.4
CAS DataBase Reference 29636-87-1(CAS DataBase Reference)
EPA Substance Registry System 1H-Imidazole-4-methanol, 5-methyl- (29636-87-1)
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H317-H319
Precautionary statements  P280-P305+P351+P338
Risk Statements  36/37/38
Safety Statements  26-36/37/39
WGK Germany  WGK 3
TSCA  TSCA listed
HS Code  2933299090
Storage Class 8A - Combustible corrosive hazardous materials
Hazard Classifications Acute Tox. 4 Oral
Skin Corr. 1B

4-HYDROXYMETHYL-5-METHYLIMIDAZOLE price More Price(22)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHR2260 Cimetidine Impurity I Pharmaceutical Secondary Standard; Certified Reference Material 29636-87-1 50mg $916 2025-07-31 Buy
TCI Chemical H0976 4-Hydroxymethyl-5-methylimidazole >96.0%(GC)(T) 29636-87-1 5g $51 2025-07-31 Buy
TCI Chemical H0976 4-Hydroxymethyl-5-methylimidazole >96.0%(GC)(T) 29636-87-1 25g $155 2025-07-31 Buy
TRC H005070 4-Hydroxymethyl-5-methylimidazole 29636-87-1 100mg $70 2021-12-16 Buy
TRC H005070 4-Hydroxymethyl-5-methylimidazole 29636-87-1 50mg $50 2021-12-16 Buy
Product number Packaging Price Buy
PHR2260 50mg $916 Buy
H0976 5g $51 Buy
H0976 25g $155 Buy
H005070 100mg $70 Buy
H005070 50mg $50 Buy

4-HYDROXYMETHYL-5-METHYLIMIDAZOLE Chemical Properties,Uses,Production

Uses

4-Hydroxymethyl-5-methylimidazole is used as an intermediate of Alosetron hydrochloride, a 5-HT3 antagonist used only for the treatment of irritable bowel syndrome (IBS) in women with predominantly severe diarrhoea. As the drug causes ischaemic colitis, a life-threatening condition in which intestinal tissue dies due to lack of blood flow to the colon. Therefore, it is no longer used.

4-HYDROXYMETHYL-5-METHYLIMIDAZOLE synthesis

51605-32-4
29636-87-1
Synthesis of 4-HYDROXYMETHYL-5-METHYLIMIDAZOLE from ETHYL 5-METHYL-1H-IMIDAZOLE-4-CARBOXYLATE

4-HYDROXYMETHYL-5-METHYLIMIDAZOLE Preparation Products And Raw materials

Raw materials

ETHYL 5-METHYL-1H-IMIDAZOLE-4-CARBOXYLATE Formaldehyde 4-Methylimidazole

Preparation Products

1H-Imidazole-4-carboxylicacid,5-methyl-,methylester(9CI) 2-(5-Methyl-1H-imidazol-4-yl)acetonitrile

4-HYDROXYMETHYL-5-METHYLIMIDAZOLE Suppliers

Global( 163)Suppliers
Supplier Tel Email Country ProdList Advantage
Changzhou Jiuwu Chemical co., Ltd.
+86-0519-85121086 +8613775162768 info@jiuwuchem.cn China 77 58
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD 		+86-13017695106 +86-13676922317 jiuyitime@fdachem.com China 16513 58
Capot Chemical Co.,Ltd. 		+86-（0）57185586718; +8613336195806 sales@capot.com China 29735 60
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21597 55
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49977 58
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29795 58
SIMAGCHEM CORP 		+86-5922680277 +86-13806087780 sale@simagchem.com China 17346 58
Dayang Chem (Hangzhou) Co.,Ltd. 		+86-0571-88938639 +8617705817739 info@dycnchem.com China 52846 58
CR Corporation Limited 		+8613062833949 fred.wen@crcorporation.cn China 8645 58
Supplier Advantage
Changzhou Jiuwu Chemical co., Ltd.
58
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD 		58
Capot Chemical Co.,Ltd. 		60
Henan Tianfu Chemical Co.,Ltd. 		55
Alchem Pharmtech,Inc. 		58
CONIER CHEM AND PHARMA LIMITED 		58
career henan chemical co 		58
SIMAGCHEM CORP 		58
Dayang Chem (Hangzhou) Co.,Ltd. 		58
CR Corporation Limited 		58

View Lastest Price from 4-HYDROXYMETHYL-5-METHYLIMIDAZOLE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(4-Methyl-1H-imidazol-5-yl)methanol pictures 2025-10-13 (4-Methyl-1H-imidazol-5-yl)methanol
29636-87-1
 US $2.00-5.00 / kg 1kg 99% 100kg ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
4-HYDROXYMETHYL-5-METHYLIMIDAZOLE pictures 2020-01-09 4-HYDROXYMETHYL-5-METHYLIMIDAZOLE
29636-87-1
 US $3.00 / KG 1KG 98% 200KG Career Henan Chemical Co

4-HYDROXYMETHYL-5-METHYLIMIDAZOLE Spectrum

4-HYDROXYMETHYL-5-METHYLIMIDAZOLE(29636-87-1)1HNMR4-HYDROXYMETHYL-5-METHYLIMIDAZOLE(29636-87-1)13CNMR4-HYDROXYMETHYL-5-METHYLIMIDAZOLE(29636-87-1)IR14-HYDROXYMETHYL-5-METHYLIMIDAZOLE(29636-87-1)IR2

29636-87-1(4-HYDROXYMETHYL-5-METHYLIMIDAZOLE)Related Search:

(5-Ethyl-1H-imidazol-4-yl)methanol 2-Cyaniminothiazolidine N-Cyanoimido-S,S-dimethyl-dithiocarbonate CIMETIDINE SULPHOXIDE DIHYDROCHLORIDE 4-[[(2-aminoethyl)thio]methyl]-5-methylimidazole
Cimetidine Amide Dihydrochloride Cimetidine N-Cyano-3-(cyanoaMino)-N'-Methyl-7,8-dithia-2,4,11-triazadodec-2-en-12-iMidaMide (CiMetidine IMpurity) 2-cyano-1,3-bis(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)guanidine N-Cyano-N'-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]thio]ethyl]carbamimidic acid methyl ester
N-cyano-N',N''-dimethylguanidine CIMETIDINE DIHYDROCHLORIDE IMP D Cysteamine hydrochloride Cimetidine Impurity 3 4,5-Imidazoledicarboxylic acid
Dimethyl 4,5-imidazoledicarboxylate 4-Methyl-5-imidazolemethanol hydrochloride Imidazole-4-methanol

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5-methyl-1h-imidazole-4-methano (5-METHYL-1H-IMIDAZOL-4-YL)-METHANOL 5-METHYL-4-HYDROXYMETHYLIMIDAZOLE 4-HYDROXYMETHYL-5-METHYLIMIDAZOLE 5-methyl-1H-imidazole-4-methanol 4-hydroxymethyl-5-methylimidazole base 5-Hydroxymethyl-4-methylimidazole 4-(Hydroxymethyl)-5-methyl-1H-imidazole 4-Methyl-1H-imidazole-5-methanol 4-Methyl-5-(hydroxymethyl)-1H-imidazole 4-Methyl-5-hydroxymethyl-1H-imidazole 4-Methyl-5-imidazolemethanol (4-Methyl-1H-imidazol-5-yl)methanol Cimetidine Impurity I HCl(EP) 4-Hydoxymethyl-5-methylimidazol 4-Hydroxymethyl-5-methylimidazole> 1H-Imidazole-5-methanol, 4-methyl- Cimetidine Impurity 15（Cimetidine EP Impurity I） 29636-87-1 (1H-Imidazole-5-methanol,4-methyl- ) Cimetidine Impurity I 4-Hydroxy methyl-5-methyl-imidazole free base 29636-87-1 pharmacetical Imidazol&Benzimidazole