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4-Hydroxymethyl-5-methylimidazole

4-Hydroxymethyl-5-methylimidazole Structure
4-Hydroxymethyl-5-methylimidazole structure
CAS No.
29636-87-1
Chemical Name:
4-Hydroxymethyl-5-methylimidazole
Synonyms
Cimetidine Impurity I;4-Methyl-5-imidazolemethanol;Cimetidine Impurity I HCl(EP);5-methyl-1h-imidazole-4-methano;4-Hydoxymethyl-5-methylimidazol;4-Methyl-1H-imidazole-5-methanol;5-methyl-1H-imidazole-4-methanol;5-Hydroxymethyl-4-methylimidazole;5-METHYL-4-HYDROXYMETHYLIMIDAZOLE;4-Hydroxymethyl-5-methylimidazole
CBNumber:
CB1360451
Molecular Formula:
C5H8N2O
Molecular Weight:
112.13
MDL Number:
MFCD00792476
MOL File:
29636-87-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:49:12
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4-Hydroxymethyl-5-methylimidazole Properties

Melting point 136°C
Boiling point 389.1±27.0 °C(Predicted)
Density 1.231
storage temp. 2-8°C
solubility DMSO (Heated), Methanol (Slightly)
form Solid
pka 13.62±0.10(Predicted)
color White to Off-White
Water Solubility almost transparency
Major Application pharmaceutical small molecule
InChI InChI=1S/C5H8N2O/c1-4-5(2-8)7-3-6-4/h3,8H,2H2,1H3,(H,6,7)
InChIKey AXJZCJSXNZZMDU-UHFFFAOYSA-N
SMILES C1NC(CO)=C(C)N=1
LogP -0.62 at 23℃ and pH8.4
CAS DataBase Reference 29636-87-1(CAS DataBase Reference)
EPA Substance Registry System 1H-Imidazole-4-methanol, 5-methyl- (29636-87-1)
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H317-H319
Precautionary statements  P280-P305+P351+P338
Risk Statements  36/37/38
Safety Statements  26-36/37/39
WGK Germany  WGK 3
TSCA  TSCA listed
HS Code  2933299090
Storage Class 8A - Combustible corrosive hazardous materials
Hazard Classifications Acute Tox. 4 Oral
Skin Corr. 1B
REACH Registrations Active

4-Hydroxymethyl-5-methylimidazole price More Price(37)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHR2260 Cimetidine Impurity I Pharmaceutical Secondary Standard; Certified Reference Material 29636-87-1 50mg $990 2026-04-30 Buy
TCI Chemical H0976 4-Hydroxymethyl-5-methylimidazole >96.0%(GC)(T) 29636-87-1 5g $55 2026-04-30 Buy
TCI Chemical H0976 4-Hydroxymethyl-5-methylimidazole >96.0%(GC)(T) 29636-87-1 25g $167 2026-04-30 Buy
TRC TRC-H005070-50MG 4-Hydroxymethyl-5-methylimidazole 29636-87-1 50mg $78 2026-06-03 Buy
TRC TRC-H005070-500MG 4-Hydroxymethyl-5-methylimidazole 29636-87-1 500mg $123 2026-06-03 Buy
Product number Packaging Price Buy
PHR2260 50mg $990 Buy
H0976 5g $55 Buy
H0976 25g $167 Buy
TRC-H005070-50MG 50mg $78 Buy
TRC-H005070-500MG 500mg $123 Buy

4-Hydroxymethyl-5-methylimidazole Chemical Properties,Uses,Production

Uses

4-Hydroxymethyl-5-methylimidazole is used as an intermediate of Alosetron hydrochloride, a 5-HT3 antagonist used only for the treatment of irritable bowel syndrome (IBS) in women with predominantly severe diarrhoea. As the drug causes ischaemic colitis, a life-threatening condition in which intestinal tissue dies due to lack of blood flow to the colon. Therefore, it is no longer used.

4-Hydroxymethyl-5-methylimidazole synthesis

51605-32-4
29636-87-1
Synthesis of 4-Hydroxymethyl-5-methylimidazole from Ethyl 5-methyl-1H-imidazole-4-carboxylate

4-Hydroxymethyl-5-methylimidazole Preparation Products And Raw materials

Raw materials

Ethyl 5-methyl-1H-imidazole-4-carboxylate Formaldehyde 4-Methylimidazole

Preparation Products

1H-Imidazole-4-carboxylicacid,5-methyl-,methylester(9CI) 2-(5-Methyl-1H-imidazol-4-yl)acetonitrile

4-Hydroxymethyl-5-methylimidazole Suppliers

Global( 166)Suppliers
Supplier Tel Email Country ProdList Advantage
Nanjing Lift Pharmaceutical Technology Co., Ltd. 18951933883 leo.feng@liftpharm.com China 312 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Beijing HwrkChemical Technology Co., Ltd 89508211 18501085097 sales.bj@hwrkchemical.com China 9407 55
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Nanjing Chemlin Chemical Co., Ltd 025-83697070 13770331960 info@chemlin.com.cn China 16305 64
Shandong Xiya Chemical Co., Ltd 13355009207 13355009207 3007715519@qq.com China 18722 57
Syntechem Co.,Ltd info@syntechem.com China 12973 57
Supplier Advantage
Nanjing Lift Pharmaceutical Technology Co., Ltd. 58
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
TCI (Shanghai) Development Co., Ltd. 81
Beijing HwrkChemical Technology Co., Ltd 55
Energy Chemical 61
Capot Chemical Co., Ltd 66
Nanjing Chemlin Chemical Co., Ltd 64
Shandong Xiya Chemical Co., Ltd 57
Syntechem Co.,Ltd 57

View Lastest Price from 4-Hydroxymethyl-5-methylimidazole manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(4-Methyl-1H-imidazol-5-yl)methanol pictures 2026-08-25 (4-Methyl-1H-imidazol-5-yl)methanol
29636-87-1
 $2.00-5.00 1kg 99% 100kg ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
4-HYDROXYMETHYL-5-METHYLIMIDAZOLE pictures 2020-01-09 4-HYDROXYMETHYL-5-METHYLIMIDAZOLE
29636-87-1
 $3.00 1KG 98% 200KG Career Henan Chemical Co

4-Hydroxymethyl-5-methylimidazole Spectrum

4-HYDROXYMETHYL-5-METHYLIMIDAZOLE(29636-87-1)1HNMR4-HYDROXYMETHYL-5-METHYLIMIDAZOLE(29636-87-1)13CNMR4-HYDROXYMETHYL-5-METHYLIMIDAZOLE(29636-87-1)IR14-HYDROXYMETHYL-5-METHYLIMIDAZOLE(29636-87-1)IR2

29636-87-1(4-Hydroxymethyl-5-methylimidazole)Related Search:

Cimetidine Amide Dihydrochloride 4-[[(2-aminoethyl)thio]methyl]-5-methylimidazole CIMETIDINE SULPHOXIDE DIHYDROCHLORIDE N-Cyanoimido-S,S-dimethyl-dithiocarbonate 2-Cyaniminothiazolidine
(5-Ethyl-1H-imidazol-4-yl)methanol Cimetidine N-Cyano-3-(cyanoaMino)-N'-Methyl-7,8-dithia-2,4,11-triazadodec-2-en-12-iMidaMide (CiMetidine IMpurity) 2-cyano-1,3-bis(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)guanidine N-Cyano-N'-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]thio]ethyl]carbamimidic acid methyl ester
N-cyano-N',N''-dimethylguanidine Cysteamine hydrochloride Cimetidine Impurity 3 Cimetidine dihydrochloride imp D Imidazole-4-methanol
4,5-Imidazoledicarboxylic acid Dimethyl 4,5-imidazoledicarboxylate 4-Methyl-5-imidazolemethanol hydrochloride

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5-methyl-1h-imidazole-4-methano (5-METHYL-1H-IMIDAZOL-4-YL)-METHANOL 5-METHYL-4-HYDROXYMETHYLIMIDAZOLE 5-methyl-1H-imidazole-4-methanol 4-hydroxymethyl-5-methylimidazole base 5-Hydroxymethyl-4-methylimidazole 4-(Hydroxymethyl)-5-methyl-1H-imidazole 4-Methyl-1H-imidazole-5-methanol 4-Methyl-5-(hydroxymethyl)-1H-imidazole 4-Methyl-5-hydroxymethyl-1H-imidazole 4-Methyl-5-imidazolemethanol (4-Methyl-1H-imidazol-5-yl)methanol Cimetidine Impurity I HCl(EP) 4-Hydoxymethyl-5-methylimidazol 4-Hydroxymethyl-5-methylimidazole> 1H-Imidazole-5-methanol, 4-methyl- Cimetidine Impurity 15（Cimetidine EP Impurity I） 29636-87-1 (1H-Imidazole-5-methanol,4-methyl- ) Cimetidine Impurity I 4-Hydroxy methyl-5-methyl-imidazole free base 4-Hydroxymethyl-5-methylimidazole 29636-87-1 pharmacetical Imidazol&Benzimidazole