(+/-)11-HETE
- CAS No.
- 73804-65-6
- Chemical Name:
- (+/-)11-HETE
- Synonyms
- (+/-)11-HETE;11-hydroxy-5(Z),8(Z),12(E),14(Z)-ETA;11-Hydroxyicosa-5,8,12,14-tetraenoic acid;(+/-)11-HYDROXY-5Z,8Z,12E,14Z-EICOSATETRAENOIC ACID
- CBNumber:
- CB1379381
- Molecular Formula:
- C20H32O3
- Molecular Weight:
- 320.47
- MDL Number:
- MFCD00065825
- MOL File:
- 73804-65-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS02 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| NFPA 704 |
|
(+/-)11-HETE price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 34500 | (±)11-HETE ≥98% | 73804-65-6 | 25μg | $91 | 2023-06-20 | Buy |
| Cayman Chemical | 34500 | (±)11-HETE ≥98% | 73804-65-6 | 50μg | $162 | 2023-06-20 | Buy |
| AHH | MT-15008 | (+/-)11-Hydroxy-5Z,8Z,12E,14Z-eicosatetraenoic acid 97% | 0.0005g | $340 | 2026-05-26 | Buy | |
| Cayman Chemical | 34500 | (±)11-HETE ≥98% | 73804-65-6 | 100μg | $286 | 2023-06-20 | Buy |
| Cayman Chemical | 34500 | (±)11-HETE ≥98% | 73804-65-6 | 250μg | $464 | 2021-12-16 | Buy |
(+/-)11-HETE Chemical Properties, Uses, Production
Description
(±)11-HETE is an oxylipin formed non-enzymatically from arachidonic acid .1,2 Levels of (±)11-HETE are increased in an in vitro model of lipid peroxidation induced by ferrous ammonium sulfate (FAS) in rat brain homogenates.3 Levels are also increased in rat liver in an in vivo model of lipid peroxidation induced by carbon tetrachloride (CCl4). It has been found in skin extracts from individuals with psoriasis and in atherosclerotic plaques.4,5
Uses
11-HETE (11-Hydroxy-5,8,12,14-eicosatetraenoic acid) is the activator for cytochrome P450. 11-HETE upregulates the mRNA expressions of CYP1B1, CYP1A1, CYP4A11, CYP4F11, and CYP4F2, induces cell hypertrophy in RL-14 cell, and exhibits potential to be used in cardiovascular diseases[1].
References
1. Powell, W.S., and Rokach, J. Biosynthesis, biological effects, and receptors of hydroxyeicosatetraenoic acids (HETEs) and oxoeicosatetraenoic acids (oxo-
2. Derogis, P.B.M.C., Chaves-Filho, A.B., and Miyamoto, S. Characterization of hydroxy and hydroperoxy polyunsaturated fatty acids by mass spectrometry Bioactive lipids in health and disease ,21-38(2019).
3. Guido, D.M., McKenna, R., and Mathews, W.R. Quantitation of hydroperoxy-
4. Camp, R.D.R., Mallet, A.I., Woollard, P.M., et al. The identification of hydroxy fatty acids in psoriatic skin Prostaglandins 26(3),431-447(1983).
5. Waddington, E., Sienuarine, K., Puddey, I., et al. Identification and quantitation of unique fatty acid oxidation products in human atherosclerotic plaque using high-
(+/-)11-HETE Preparation Products And Raw materials
Raw materials
Preparation Products
(+/-)11-HETE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Yichang Zhongyitai Trading Co., Ltd. | 0717-6449896 13886658719 | root@zhongyitai.com | China | 1978 | 58 |
| Alfa Chemistry | 1-516-6625404 | support@alfa-chemistry.com | United States | 9170 | 60 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 400-920-5774 | sales@glpbio.cn | China | 6705 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8137 | 58 |
| amyjet | 4006800868;027-59626688 18771149750 | sales@amyjet.com | China | 2909 | 58 |
| SHANGHAI ZZBIO CO., LTD. | 18019219489 18901678489 | tech@zzbioco.com | China | 12062 | 58 |
