1-(3-Bromophenyl)pyrrolidine
- CAS No.
- 219928-13-9
- Chemical Name:
- 1-(3-Bromophenyl)pyrrolidine
- Synonyms
- N-(3-BROMOPHENYL)PYRROLIDINE;1-(3-Bromophenyl)pyrrolidine;Pyrrolidine, 1-(3-broMophenyl)-;1-(3-Bromophenyl)pyrrolidine97%;1-(3-Bromophenyl)pyrrolidine 97%
- CBNumber:
- CB1384763
- Molecular Formula:
- C10H12BrN
- Molecular Weight:
- 226.11
- MDL Number:
- MFCD04112531
- MOL File:
- 219928-13-9.mol
- MSDS File:
- SDS
| Boiling point | 76/0.1mm |
|---|---|
| Density | 1.411±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| pka | 4.51±0.40(Predicted) |
| Appearance | Off-white to brown Solid |
| CAS DataBase Reference | 219928-13-9 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302+H312+H332-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280-P305+P351+P338 | |||||||||
| Hazard Note | Harmful | |||||||||
| HS Code | 2933998090 | |||||||||
| NFPA 704 |
|
1-(3-Bromophenyl)pyrrolidine price More Price(41)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR9182 | 1-(3-Bromophenyl)pyrrolidine 97% | 219928-13-9 | 250mg | $21 | 2026-06-04 | Buy |
| Activate Scientific | AS39918 | 1-(3-Bromophenyl)pyrrolidine 97% | 219928-13-9 | 1g | $54 | 2026-06-04 | Buy |
| Activate Scientific | AS39918 | 1-(3-Bromophenyl)pyrrolidine 97% | 219928-13-9 | 5g | $217 | 2026-06-04 | Buy |
| Matrix Scientific | 119763 | 1-(3-Bromophenyl)pyrrolidine | 219928-13-9 | 1.00g | $162 | 2026-05-18 | Buy |
| Matrix Scientific | 119763 | 1-(3-Bromophenyl)pyrrolidine | 219928-13-9 | 5.00g | $504 | 2026-05-18 | Buy |
1-(3-Bromophenyl)pyrrolidine Chemical Properties,Uses,Production
Application
1-(3-bromophenyl)pyrrole is a heterocyclic organic compound that can be used to prepare lithium 3-(pyrrolidin-1-yl)benzenesulfinate.
Synthesis
123-75-1
108-36-1
219928-13-9
1. To a 500 mL three-necked round-bottomed flask was added a toluene solution (300 mL) of 1,3-dibromobenzene (20 g, 84.78 mmol, 1.00 eq.) under nitrogen protection. 2. To the reaction system was added pyrrolidine (6.03 g, 84.80 mmol, 1.00 eq.), Pd(OAc)2 (190 mg, 0.85 mmol, 0.01 eq.), BINAP (760 mg, 2.53 mmol, 0.03 eq.) and Cs2CO3 (69.1 g, 211.96 mmol, 2.50 equivalent). 3. The reaction mixture was stirred in an oil bath at 120 °C overnight and the progress of the reaction was monitored by TLC (Expander: EtOAc/PE = 1:5). 4. After completion of the reaction, the reaction mixture was filtered and the filtrate was concentrated under reduced pressure by rotary evaporator. 5. The residue was purified by column chromatography (eluent: PE) to afford 8.51 g (45% yield) of 1-(3-bromophenyl)pyrrolidine as a pale yellow liquid. 6. The product was analyzed by LC-MS. 6. The product was characterized by LC-MS: [M+H]+ m/z calculated value C10H13BrN 226, measured value 226.
References
[1] Bioorganic and Medicinal Chemistry, 2017, vol. 25, # 24, p. 6427 - 6434
[2] Tetrahedron, 2008, vol. 64, # 13, p. 2938 - 2950
[3] Patent: EP3239143, 2017, A2. Location in patent: Paragraph 0165
[4] Patent: US2008/318941, 2008, A1. Location in patent: Page/Page column 44
[5] Patent: US2008/200471, 2008, A1. Location in patent: Page/Page column 66
1-(3-Bromophenyl)pyrrolidine Preparation Products And Raw materials
Raw materials
Preparation Products
1-(3-Bromophenyl)pyrrolidine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Shijiazhuang Sdyano Fine Chemical Co., Ltd. | 0311-89250318 13582355795 | master@sjzsdyn.com | China | 2776 | 65 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| Shandong Xiya Chemical Co., Ltd | 13355009207 13355009207 | 3007715519@qq.com | China | 18722 | 57 |
| Syntechem Co.,Ltd | info@syntechem.com | China | 12973 | 57 | |
| 9ding chemical ( Shanghai) Limited | 4009209199 | sales@9dingchem.com | China | 18201 | 56 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29985 | 65 |
| Guangzhou Isun Pharmaceutical Co., Ltd | 020-39119399 18927568969 | isunpharm@qq.com | China | 4773 | 55 |
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