Bupivacaine hydrochloride
- CAS No.
- 14252-80-3
- Chemical Name:
- Bupivacaine hydrochloride
- Synonyms
- Sensorcaine;Bupivacaine HCI;ah-2250;Bupivocoine HCl;Bupivacaine HCL API;marcainehydrochloride;Bupivacaine HCL (USP);BUPIVACAINE HYDROCHLORIDE;Bupivacaine Hydrochloride, USP;Bupivacaine hydrochloride,>98%
- CBNumber:
- CB1386202
- Molecular Formula:
- C18H28N2O.ClH
- Molecular Weight:
- 324.89
- MDL Number:
- MFCD00941462
- MOL File:
- 14252-80-3.mol
| Melting point | 249-2510C |
|---|---|
| storage temp. | Refrigerator |
| solubility | Soluble in water, freely soluble in alcohol. |
| form | Solid |
| color | White to Off-White |
| Stability | Hygroscopic |
| InChI | InChI=1S/C18H28N2O.ClH/c1-4-5-12-20-13-7-6-11-16(20)18(21)19-17-14(2)9-8-10-15(17)3;/h8-10,16H,4-7,11-13H2,1-3H3,(H,19,21);1H |
| InChIKey | SIEYLFHKZGLBNX-UHFFFAOYSA-N |
| SMILES | C1(CCCCN1CCCC)C(=O)NC1C(C)=CC=CC=1C.Cl |
| CAS DataBase Reference | 14252-80-3(CAS DataBase Reference) |
| FDA UNII | 7TQO7W3VT8 |
| NCI Dictionary of Cancer Terms | bupivacaine hydrochloride; Sensorcaine |
| NCI Drug Dictionary | bupivacaine hydrochloride |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H330-H300-H310 |
| Precautionary statements | P264-P270-P301+P310-P321-P330-P405-P501-P260-P271-P284-P304+P340-P310-P320-P403+P233-P405-P501-P262-P264-P270-P280-P302+P350-P310-P322-P361-P363-P405-P501 |
| Hazard Codes | T+ |
| Risk Statements | 26/27/28 |
| Safety Statements | 22-36/37/39-45 |
| RIDADR | UN 2811 6.1/PG 2 |
| WGK Germany | 3 |
| RTECS | TK6125000 |
| HazardClass | 6.1(b) |
| PackingGroup | III |
| HS Code | 2933399090 |
| Toxicity | LD50 in mice (mg/kg): 7.8 i.v., 82 s.c. (Henn, Brattsand) |
Bupivacaine hydrochloride price More Price(12)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 1078507 | Bupivacaine hydrochloride United States Pharmacopeia (USP) Reference Standard | 14252-80-3 | 300mg | $467 | 2025-07-31 | Buy |
| aablocks | AA00ILKB | 2-Piperidinecarboxamide, 1-butyl-N-(2,6-dimethylphenyl)-, hydrochloride (1:1) ≥98% | 14252-80-3 | 1g | $22 | 2026-05-29 | Buy |
| aablocks | AA00ILKB | 2-Piperidinecarboxamide, 1-butyl-N-(2,6-dimethylphenyl)-, hydrochloride (1:1) ≥98% | 14252-80-3 | 5g | $35 | 2026-05-29 | Buy |
| Crysdot | CD11259235 | 1-Butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide hydrochloride 97% | 14252-80-3 | 10g | $38 | 2026-05-26 | Buy |
| Crysdot | CD11259235 | 1-Butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide hydrochloride 97% | 14252-80-3 | 25g | $74 | 2026-05-26 | Buy |
Bupivacaine hydrochloride Chemical Properties,Uses,Production
Chemical Properties
White Solid
Uses
antineoplastic
Uses
Bupivacaine Hydrochloride is the salt form of Bupivacaine (B689561); is a sodium channel blocker, local anesthetic.
Definition
ChEBI: Bupivacaine hydrochloride (anhydrous) is a racemate composed of equimolar amounts of dextrobupivacaine hydrochloride and levobupivacaine hydrochloride. The monohydrate form is commonly used as a local anaesthetic. It has a role as an adrenergic antagonist, an amphiphile, an EC 3.1.1.8 (cholinesterase) inhibitor, an EC 3.6.3.8 (Ca(2+)-transporting ATPase) inhibitor and a local anaesthetic. It contains a levobupivacaine hydrochloride (anhydrous), a dextrobupivacaine hydrochloride (anhydrous) and a bupivacaine(1+).
brand name
Marcaine (Hospira); Sensorcaine (AstraZeneca).
Biological Functions
Bupivacaine hydrochloride (Marcaine, Sensorcaine) has particularly long action, and some nerve blocks last more than 24 hours; this is often an advantage for postoperative analgesia. Its use for epidural anesthesia in obstetrics has attracted interest because it can relieve the pain of labor at concentrations as low as 0.125% while permitting some motor activity of abdominal muscles to aid in expelling the fetus. The lower concentration minimizes the possibility of cardiac toxicity. Fetal drug concentrations remain low, and drug-induced neurobehavioral changes are not observed in the newborn. Bupivacaine also is approved for spinal anesthesia and is approximately four times more potent and more toxic than mepivacaine and lidocaine. It can be used with or without epinephrine.
Clinical Use
Bupivacaine hydrochloride injection is a clear, colorless solution intended for use in adults to provide local or regional anesthesia or analgesia. It is suitable for various applications, including surgical procedures, dental and oral surgery, diagnostic and therapeutic interventions, as well as obstetric procedures.
Bupivacaine hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shandong Mingfeng Pharmaceutical and Technology Co. Ltd | 053155551677 15315114555 | 1345456643@qq.com | China | 298 | 58 |
| Shanghai Boyle Chemical Co., Ltd. | sales@boylechem.com | China | 2915 | 55 | |
| Chembest Research Laboratories Limited | 021-20908456 | sales@BioChemBest.com | China | 5996 | 61 |
| Beijing HwrkChemical Technology Co., Ltd | 89508211 18501085097 | sales.bj@hwrkchemical.com | China | 9407 | 55 |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Jia Xing Isenchem Co.,Ltd | 0573-85285100 18627885956 | isenchem@163.com | China | 9389 | 66 |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14098 | 59 |
| Chemsky (shanghai) International Co.,Ltd | 021-50135380 | shchemsky@sina.com | China | 15350 | 60 |
Related articles
- Bupivacaine hydrochloride: mechanism of action, clinical applications and safety
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- Nov 20,2023
- Bupivacaine hydrochloride--Metabolism, Excretion, Pediatric use and recommended dose
- Bupivacaine hydrochloride has particularly long action, and some nerve blocks last more than 24 hours; this is often an advant....
- Oct 15,2020
View Lastest Price from Bupivacaine hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-25 | Bupivacaine hydrochloride
14252-80-3
|
1KG | 0.99 | 1000KG | Shaanxi Xianhe Biotech Co., Ltd | ||
 |
2026-08-20 | Bupivacaine hydrochloride USP/EP/BP
14252-80-3
|
$1.10 | 1g | 99.9% | 100 Tons Min | Dideu Industries Group Limited | |
 |
2026-08-12 | Bupivacaine hydrochloride
14252-80-3
|
$365.00 | 1KG | 99% | 1T | Baoji Guokang Healthchem Co., Ltd. |
-
- Bupivacaine hydrochloride
14252-80-3
- $0.00
- 0.99
- Shaanxi Xianhe Biotech Co., Ltd
-
- Bupivacaine hydrochloride USP/EP/BP
14252-80-3
- $1.10
- 99.9%
- Dideu Industries Group Limited
-
- Bupivacaine hydrochloride
14252-80-3
- $365.00
- 99%
- Baoji Guokang Healthchem Co., Ltd.
